| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.162114 |
| VIM | vimentin | 0.115388 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0922511 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0740413 |
| ENO1 | enolase 1, (alpha) | 0.0689239 |
| ACTG1 | actin gamma 1 | 0.0677664 |
| CD109 | CD109 molecule | 0.0549534 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0527712 |
| GPC6 | glypican 6 | 0.0509157 |
| ANXA2 | annexin A2 | 0.0500061 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0487823 |
| NDRG1 | N-myc downstream regulated 1 | 0.047021 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0461908 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0458791 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0446345 |
| ACTN1 | actinin, alpha 1 | 0.0417289 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0412353 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0410482 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0398185 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0354108 |
| SFTPA2 | surfactant protein A2 | 0.0346805 |
| RTN4 | reticulon 4 | 0.0330484 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0323535 |
| MCL1 | myeloid cell leukemia 1 | 0.0321924 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0321284 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0315673 |
| VCL | vinculin | 0.0314722 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0309506 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0305611 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0300971 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0293314 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0292602 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0290695 |
| PLEC | plectin | 0.0285668 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0283684 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0276541 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0272698 |
| TPM4 | tropomyosin 4 | 0.0271898 |
| A2M | alpha-2-macroglobulin | 0.0270897 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0268835 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0264841 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0263566 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0260473 |
| CABIN1 | calcineurin binding protein 1 | 0.0251672 |
| FLNA | filamin A, alpha | 0.0243303 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0242715 |
| CALR | calreticulin | 0.0242368 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0239033 |
| ZYX | zyxin | 0.0238837 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.023811 |
| RPL37A | ribosomal protein L37a | 0.023726 |
| RPL3 | ribosomal protein L3 | 0.0229962 |
| CENPF | centromere protein F, 350/400kDa | 0.0229681 |
| ZNF292 | zinc finger protein 292 | 0.0222955 |
| POTEF | POTE ankyrin domain family, member F | 0.0218909 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0214422 |
| RUNX1 | runt-related transcription factor 1 | 0.0212791 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0212786 |
| LIMA1 | LIM domain and actin binding 1 | 0.0206875 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0205462 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0203111 |
| B2M | beta-2-microglobulin | 0.0202315 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0202173 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.020203 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0200984 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0197908 |
| SDC2 | syndecan 2 | 0.0197347 |
| MYO1E | myosin IE | 0.0197162 |
| CALD1 | caldesmon 1 | 0.0195624 |
| IGF2 | insulin-like growth factor 2 | 0.0185519 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0184732 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0184607 |
| EGR1 | early growth response 1 | 0.0182522 |
| RHOA | ras homolog family member A | 0.0182112 |
| PDLIM5 | PDZ and LIM domain 5 | 0.018197 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0181429 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0181323 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0181322 |
| FMNL2 | formin-like 2 | 0.0180416 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0180262 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0179914 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0179068 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0176837 |
| SQSTM1 | sequestosome 1 | 0.0176406 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0175235 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0174482 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0174406 |
| NAV2 | neuron navigator 2 | 0.0174389 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0174047 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0174017 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0173525 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0172763 |
| MRTFA | myocardin related transcription factor A | 0.0172669 |
| FTL | ferritin, light polypeptide | 0.0171362 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0170929 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0169575 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0169534 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0168565 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.01685 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0168483 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0869002 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0721603 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0612549 |
| NLGN1 | neuroligin 1 | -0.0514384 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0484408 |
| VGF | VGF nerve growth factor inducible | -0.0441623 |
| MACROD2 | MACRO domain containing 2 | -0.0337386 |
| CDK14 | cyclin-dependent kinase 14 | -0.03348 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0323939 |
| NAV3 | neuron navigator 3 | -0.0307022 |
| HMCN1 | hemicentin 1 | -0.0305985 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0293254 |
| RFX7 | regulatory factor X, 7 | -0.0268531 |
| EHBP1 | EH domain binding protein 1 | -0.0246549 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0231552 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.02225 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0220204 |
| LSAMP | limbic system-associated membrane protein | -0.0207734 |
| INSIG1 | insulin induced gene 1 | -0.019949 |
| MT1X | metallothionein 1X | -0.0188062 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -0.0179403 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0177544 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0177448 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0175659 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -0.0168124 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0164076 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0164052 |
| NEGR1 | neuronal growth regulator 1 | -0.0160209 |
| SCFD2 | sec1 family domain containing 2 | -0.0158297 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0156658 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0155285 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0152653 |
| CFAP20DC | CFAP20 domain containing | -0.0152491 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.0149945 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0149705 |
| FHIT | fragile histidine triad | -0.0148541 |
| IER3 | immediate early response 3 | -0.0147171 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0146768 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0145708 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0141961 |
| DST | dystonin | -0.0139061 |
| MEIS2 | Meis homeobox 2 | -0.0137714 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0135909 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.013536 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0134867 |
| NRCAM | neuronal cell adhesion molecule | -0.0134698 |
| TULP4 | tubby like protein 4 | -0.013035 |
| TMSB10 | thymosin beta 10 | -0.0127371 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0125725 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0125322 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0124037 |
| IGF1R | insulin-like growth factor 1 receptor | -0.012232 |
| EXOC4 | exocyst complex component 4 | -0.0121778 |
| EPHA3 | EPH receptor A3 | -0.0120719 |
| FRMD6 | FERM domain containing 6 | -0.0120716 |
| NBAS | neuroblastoma amplified sequence | -0.012009 |
| AGMO | alkylglycerol monooxygenase | -0.0119926 |
| ZNF704 | zinc finger protein 704 | -0.011769 |
| GSN | gelsolin | -0.0117091 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0116349 |
| FGF13 | fibroblast growth factor 13 | -0.0115645 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0115136 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0113176 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0112844 |
| RRBP1 | ribosome binding protein 1 | -0.0112566 |
| RNF24 | ring finger protein 24 | -0.0111769 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0109935 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0109676 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | -0.0107712 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0107527 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0106262 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0105915 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.010408 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0103956 |
| ATRNL1 | attractin-like 1 | -0.0103548 |
| FRMD5 | FERM domain containing 5 | -0.0100688 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00995509 |
| PTK2 | protein tyrosine kinase 2 | -0.00995137 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00993883 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.00991073 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00986777 |
| DOCK10 | dedicator of cytokinesis 10 | -0.00979746 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.00968893 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00964918 |
| RASAL2 | RAS protein activator like 2 | -0.00956589 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00951115 |
| NAV1 | neuron navigator 1 | -0.00944619 |
| FIGN | fidgetin | -0.00944412 |
| TRIM2 | tripartite motif containing 2 | -0.00936377 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0093281 |
| ZNF536 | zinc finger protein 536 | -0.00931052 |
| SSH2 | slingshot protein phosphatase 2 | -0.00918912 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00908049 |
| FUS | FUS RNA binding protein | -0.00908018 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0090652 |
| ATXN10 | ataxin 10 | -0.00904966 |
| NCOA2 | nuclear receptor coactivator 2 | -0.00900593 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00885233 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.00882614 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00870108 |
