| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the NVP-BHG712_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.171869 |
| LAMB3 | laminin, beta 3 | 0.135932 |
| B2M | beta-2-microglobulin | 0.135255 |
| HLA-A | major histocompatibility complex, class I, A | 0.132573 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.110221 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0885429 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0846936 |
| EZR | ezrin | 0.0799259 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0794525 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0778375 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0768455 |
| MCL1 | myeloid cell leukemia 1 | 0.0762575 |
| PLEC | plectin | 0.0752419 |
| VIM | vimentin | 0.0741325 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0721774 |
| OPTN | optineurin | 0.0677531 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0676164 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0674887 |
| NDRG1 | N-myc downstream regulated 1 | 0.0670331 |
| KRT19 | keratin 19, type I | 0.066828 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0659272 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0658883 |
| HLA-B | major histocompatibility complex, class I, B | 0.0579808 |
| TPM4 | tropomyosin 4 | 0.0578042 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0575781 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0548352 |
| POTEF | POTE ankyrin domain family, member F | 0.0535774 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0529973 |
| HLA-C | major histocompatibility complex, class I, C | 0.0529723 |
| S100A6 | S100 calcium binding protein A6 | 0.0516319 |
| LDHA | lactate dehydrogenase A | 0.0510871 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0508509 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0503393 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0499378 |
| ANKRD11 | ankyrin repeat domain 11 | 0.049838 |
| ENO1 | enolase 1, (alpha) | 0.0492652 |
| TPM3 | tropomyosin 3 | 0.0484642 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0482377 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0466907 |
| PLAU | plasminogen activator, urokinase | 0.0463613 |
| TGM2 | transglutaminase 2 | 0.0457685 |
| VEGFA | vascular endothelial growth factor A | 0.0444067 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0442492 |
| HMGA1 | high mobility group AT-hook 1 | 0.0439554 |
| PCBP2 | poly(rC) binding protein 2 | 0.0435836 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0433658 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0423133 |
| ANXA2 | annexin A2 | 0.041926 |
| RPS3 | ribosomal protein S3 | 0.0412972 |
| PKM | pyruvate kinase, muscle | 0.0409377 |
| TAPBP | TAP binding protein (tapasin) | 0.0406377 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0406025 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0402423 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0401263 |
| FOSL1 | FOS-like antigen 1 | 0.0400329 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0398328 |
| BCL2L1 | BCL2-like 1 | 0.0397677 |
| HLA-E | major histocompatibility complex, class I, E | 0.0392913 |
| RTN4 | reticulon 4 | 0.0376316 |
| EGR1 | early growth response 1 | 0.0375326 |
| RPL3 | ribosomal protein L3 | 0.0372427 |
| RPS12 | ribosomal protein S12 | 0.0367179 |
| LCN2 | lipocalin 2 | 0.0366584 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0364412 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0363561 |
| RPL37A | ribosomal protein L37a | 0.0360869 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0352924 |
| APOL1 | apolipoprotein L, 1 | 0.0348465 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.034656 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0341134 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0340902 |
| DTNA | dystrobrevin, alpha | 0.034039 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0338623 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0335558 |
| ARRDC3 | arrestin domain containing 3 | 0.0334333 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0329676 |
| HDGF | hepatoma-derived growth factor | 0.0327768 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0325139 |
| RACK1 | receptor for activated C kinase 1 | 0.0323966 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0323742 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0323427 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0321961 |
| RPL37 | ribosomal protein L37 | 0.0320438 |
| GOLGB1 | golgin B1 | 0.03176 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0310782 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0308114 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0307693 |
| MT1E | metallothionein 1E | 0.0307299 |
| STC2 | stanniocalcin 2 | 0.0301941 |
| C3 | complement component 3 | 0.0298047 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0290079 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0287885 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.028253 |
| UBC | ubiquitin C | 0.0275907 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0275715 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0275388 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.027364 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.027208 |
| RPS8 | ribosomal protein S8 | 0.0271605 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0270907 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT1X | metallothionein 1X | -0.135775 |
| MT2A | metallothionein 2A | -0.125077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100461 |
| TMSB10 | thymosin beta 10 | -0.0891419 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0865874 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0830406 |
| ASPH | aspartate beta-hydroxylase | -0.0791074 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0622873 |
| PTMA | prothymosin, alpha | -0.0602001 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.060112 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0586963 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0556187 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0515437 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0488199 |
| MYOF | myoferlin | -0.0487393 |
| EHBP1 | EH domain binding protein 1 | -0.0469754 |
| NRG3 | neuregulin 3 | -0.0459153 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0456405 |
| MMP7 | matrix metallopeptidase 7 | -0.0454706 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0440977 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.042973 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0423848 |
| NCKAP5 | NCK-associated protein 5 | -0.0421182 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0420479 |
| PCDH7 | protocadherin 7 | -0.0416182 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0411495 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0395969 |
| NABP1 | nucleic acid binding protein 1 | -0.0391524 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0382332 |
| DST | dystonin | -0.037911 |
| FTL | ferritin, light polypeptide | -0.0376039 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0371294 |
| CD2AP | CD2-associated protein | -0.0371161 |
| SYNRG | synergin, gamma | -0.0366185 |
| LMO7 | LIM domain 7 | -0.0360513 |
| H1-0 | H1.0 linker histone | -0.0345402 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0339568 |
| RRBP1 | ribosome binding protein 1 | -0.0338712 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0334934 |
| IER3 | immediate early response 3 | -0.0334737 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0330256 |
| EFNA5 | ephrin-A5 | -0.0320965 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0319459 |
| PRKCA | protein kinase C, alpha | -0.0314869 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0308485 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.029969 |
| RAD51B | RAD51 paralog B | -0.0297918 |
| RASAL2 | RAS protein activator like 2 | -0.0294601 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0291824 |
| MEF2A | myocyte enhancer factor 2A | -0.029012 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0288555 |
| PRELID2 | PRELI domain containing 2 | -0.0286585 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0282782 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0282467 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0281432 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0278195 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0276646 |
| RPLP1 | ribosomal protein, large, P1 | -0.026382 |
| AK1 | adenylate kinase 1 | -0.0263658 |
| RPS21 | ribosomal protein S21 | -0.0260929 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0258692 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0257264 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0254682 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0253893 |
| RNF213 | ring finger protein 213 | -0.0252249 |
| FUS | FUS RNA binding protein | -0.0251561 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0246441 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0246376 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0242968 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0242687 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0235262 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0222426 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0221096 |
| SMYD3 | SET and MYND domain containing 3 | -0.0220673 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0219927 |
| TC2N | tandem C2 domains, nuclear | -0.0218367 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0217737 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0216459 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0212913 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0212812 |
| PARD3 | par-3 family cell polarity regulator | -0.0211221 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0208829 |
| AHNAK | AHNAK nucleoprotein | -0.0207225 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0205879 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.020357 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0203053 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0201487 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0200951 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0200088 |
| ZNF217 | zinc finger protein 217 | -0.0196883 |
| XAF1 | XIAP associated factor 1 | -0.0193834 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0192752 |
| CCNI | cyclin I | -0.0189755 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.018888 |
| INTS6 | integrator complex subunit 6 | -0.0188026 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0186676 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0186134 |
| NEK7 | NIMA-related kinase 7 | -0.0184723 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0184286 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0183659 |
