| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the NVP-BHG712_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0507538 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0505659 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0392049 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0303686 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0278757 |
| RPS3 | ribosomal protein S3 | 0.0261509 |
| NDRG1 | N-myc downstream regulated 1 | 0.0246208 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0223373 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0222397 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0215265 |
| VEGFA | vascular endothelial growth factor A | 0.0212828 |
| RORA | RAR-related orphan receptor A | 0.0211979 |
| TPM1 | tropomyosin 1 (alpha) | 0.0206815 |
| MCL1 | myeloid cell leukemia 1 | 0.0206742 |
| TLE4 | transducin-like enhancer of split 4 | 0.0199623 |
| HSPA8 | heat shock 70kDa protein 8 | 0.019946 |
| FERMT2 | fermitin family member 2 | 0.0189753 |
| PCBP2 | poly(rC) binding protein 2 | 0.0189505 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0188796 |
| ANGPTL4 | angiopoietin-like 4 | 0.0181292 |
| FLNB | filamin B, beta | 0.0179315 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0178981 |
| HELZ | helicase with zinc finger | 0.0172997 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0171747 |
| RPL3 | ribosomal protein L3 | 0.0169647 |
| LIMA1 | LIM domain and actin binding 1 | 0.0168124 |
| XPO1 | exportin 1 | 0.016728 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0167099 |
| SQSTM1 | sequestosome 1 | 0.0166499 |
| WDR45B | WD repeat domain 45B | 0.0166121 |
| VCL | vinculin | 0.0164845 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0162785 |
| FAM13A | family with sequence similarity 13, member A | 0.0161261 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.015855 |
| PTEN | phosphatase and tensin homolog | 0.0157386 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0156925 |
| PLEC | plectin | 0.0156199 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.015579 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0155524 |
| RPL7 | ribosomal protein L7 | 0.0154721 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0154633 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0153895 |
| YTHDC1 | YTH domain containing 1 | 0.0151459 |
| PALLD | palladin, cytoskeletal associated protein | 0.0150477 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0148425 |
| MXI1 | MAX interactor 1, dimerization protein | 0.014482 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0143548 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0143058 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0142999 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0137763 |
| CD46 | CD46 molecule, complement regulatory protein | 0.013695 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0136793 |
| MYO1E | myosin IE | 0.0133575 |
| FAT1 | FAT atypical cadherin 1 | 0.0130911 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.012991 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0129625 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0128966 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0128329 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0128012 |
| ARRDC3 | arrestin domain containing 3 | 0.0127925 |
| DPH6 | diphthamine biosynthesis 6 | 0.012674 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0126191 |
| FLNA | filamin A, alpha | 0.0123712 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0123551 |
| DUSP10 | dual specificity phosphatase 10 | 0.012317 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0120356 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0119732 |
| SYNPO2 | synaptopodin 2 | 0.01187 |
| CDK19 | cyclin-dependent kinase 19 | 0.011765 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0117128 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0116305 |
| HBS1L | HBS1-like translational GTPase | 0.0116103 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | 0.0115985 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0115934 |
| RACK1 | receptor for activated C kinase 1 | 0.0114874 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0114466 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0114172 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0113823 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.011332 |
| PCBP3 | poly(rC) binding protein 3 | 0.0111744 |
| RGS4 | regulator of G-protein signaling 4 | 0.0111678 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0111167 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0110914 |
| TOX | thymocyte selection-associated high mobility group box | 0.0110896 |
| OGA | O-GlcNAcase | 0.011047 |
| RPS17 | ribosomal protein S17 | 0.0109998 |
| RTN4 | reticulon 4 | 0.0109546 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0109068 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0108958 |
| RPS12 | ribosomal protein S12 | 0.0108092 |
| CPNE1 | copine I | 0.0107895 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0107722 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0107253 |
| MACROD2 | MACRO domain containing 2 | 0.0106583 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0106521 |
| RPS18 | ribosomal protein S18 | 0.0106164 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0106111 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0106053 |
| PRELID2 | PRELI domain containing 2 | 0.0105852 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0105411 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.20346 |
| LSAMP | limbic system-associated membrane protein | -0.190406 |
| IGF2 | insulin-like growth factor 2 | -0.145876 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.107478 |
| PTMA | prothymosin, alpha | -0.104031 |
| EXT1 | exostosin glycosyltransferase 1 | -0.101176 |
| COL1A1 | collagen, type I, alpha 1 | -0.0916134 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0877909 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0830303 |
| COL3A1 | collagen, type III, alpha 1 | -0.0827858 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0747431 |
| PRKCA | protein kinase C, alpha | -0.0746882 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0735771 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.070179 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0696026 |
| SYT1 | synaptotagmin I | -0.0658204 |
| FMN1 | formin 1 | -0.0634573 |
| CRH | corticotropin releasing hormone | -0.0599085 |
| ZNF804A | zinc finger protein 804A | -0.0570511 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0566094 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0546559 |
| RPS24 | ribosomal protein S24 | -0.0511714 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0496619 |
| VIM | vimentin | -0.0452076 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0437134 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0434933 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0431895 |
| MEIS2 | Meis homeobox 2 | -0.0417731 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.0417199 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0417015 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0414336 |
| RPL19 | ribosomal protein L19 | -0.0399859 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0389698 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0379467 |
| MSI2 | musashi RNA-binding protein 2 | -0.0374659 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0373116 |
| BPTF | bromodomain PHD finger transcription factor | -0.0370343 |
| KLHL13 | kelch-like family member 13 | -0.0368816 |
| TRIB2 | tribbles pseudokinase 2 | -0.0351806 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0348325 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0347495 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0346427 |
| ATXN10 | ataxin 10 | -0.0344183 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.034203 |
| MX2 | MX dynamin-like GTPase 2 | -0.0335699 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0333079 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.033214 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0329942 |
| GPC5 | glypican 5 | -0.0329579 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0322569 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0322374 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0321234 |
| AOPEP | aminopeptidase O (putative) | -0.0315413 |
| CNTN4 | contactin 4 | -0.0314007 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0311608 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.030549 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0302472 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0298468 |
| FRMD4A | FERM domain containing 4A | -0.0297347 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0297344 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0296126 |
| TCF12 | transcription factor 12 | -0.029332 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0292807 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0292557 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0286509 |
| GPATCH8 | G patch domain containing 8 | -0.0281131 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0278425 |
| GNAS | GNAS complex locus | -0.0277098 |
| RPL35A | ribosomal protein L35a | -0.0274578 |
| RBMX | RNA binding motif protein, X-linked | -0.0269936 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0266119 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0264319 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0260101 |
| IER3 | immediate early response 3 | -0.0259298 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0257367 |
| H3-3B | H3.3 histone B | -0.025484 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0252274 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0250154 |
| NREP | neuronal regeneration related protein | -0.024746 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0245939 |
| TMSB10 | thymosin beta 10 | -0.0245678 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.024522 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0244281 |
| RPL32 | ribosomal protein L32 | -0.0243455 |
| SCG2 | secretogranin II | -0.0242241 |
| THBS1 | thrombospondin 1 | -0.0240643 |
| MAP1B | microtubule-associated protein 1B | -0.0239087 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0235356 |
| PARD3 | par-3 family cell polarity regulator | -0.023255 |
| USP34 | ubiquitin specific peptidase 34 | -0.0226736 |
| RPL38 | ribosomal protein L38 | -0.0226708 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0226586 |
| CUX1 | cut-like homeobox 1 | -0.0224451 |
| PLAT | plasminogen activator, tissue | -0.0223843 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.021838 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.02183 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0218109 |
| EXOC4 | exocyst complex component 4 | -0.0213968 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0212676 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0212335 |
