| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | 0.0310135 |
| PLEC | plectin | 0.0276198 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0262826 |
| INTS6 | integrator complex subunit 6 | 0.0245287 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0219945 |
| PRRC2A | proline-rich coiled-coil 2A | 0.013871 |
| LRRC23 | leucine rich repeat containing 23 | 0.0130847 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0122375 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0107682 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0107657 |
| ASS1 | argininosuccinate synthase 1 | 0.0101984 |
| HOMER1 | homer scaffolding protein 1 | 0.0100279 |
| TGFB1 | transforming growth factor, beta 1 | 0.00996383 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.00995734 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.00967962 |
| RPL3 | ribosomal protein L3 | 0.00942475 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.00937474 |
| KLHL29 | kelch-like family member 29 | 0.0093736 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.00930575 |
| PGM3 | phosphoglucomutase 3 | 0.0092062 |
| FLNA | filamin A, alpha | 0.00920245 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00917891 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00907122 |
| RCC1 | regulator of chromosome condensation 1 | 0.00900949 |
| LASP1 | LIM and SH3 protein 1 | 0.00887921 |
| POU2F2 | POU class 2 homeobox 2 | 0.00872426 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.00868644 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.00851218 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00841253 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.00825807 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.00823521 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00806547 |
| TLN1 | talin 1 | 0.00801084 |
| BAIAP2 | BAI1-associated protein 2 | 0.00788859 |
| EGR1 | early growth response 1 | 0.00779261 |
| SEC24D | SEC24 family member D | 0.00777891 |
| TUFT1 | tuftelin 1 | 0.00774852 |
| ARRDC3 | arrestin domain containing 3 | 0.00769125 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00744346 |
| RPS26 | ribosomal protein S26 | 0.00740863 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.00740623 |
| FOXO3 | forkhead box O3 | 0.00732279 |
| RUNX1 | runt-related transcription factor 1 | 0.00731934 |
| VEGFA | vascular endothelial growth factor A | 0.0072793 |
| NXF1 | nuclear RNA export factor 1 | 0.00721131 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0071963 |
| KLF10 | Kruppel-like factor 10 | 0.00709291 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.00707203 |
| CLDND1 | claudin domain containing 1 | 0.00690248 |
| EFNB2 | ephrin-B2 | 0.00682526 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.00679163 |
| IGF2 | insulin-like growth factor 2 | 0.00676163 |
| CEP250 | centrosomal protein 250kDa | 0.0067577 |
| SURF4 | surfeit 4 | 0.00668455 |
| TRIM72 | tripartite motif containing 72, E3 ubiquitin protein ligase | 0.00668051 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.00660964 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00651703 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.00648451 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.00647983 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00644749 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.00643904 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.00639777 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00639548 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00639132 |
| RPL29 | ribosomal protein L29 | 0.00636426 |
| FBXO32 | F-box protein 32 | 0.00634393 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00633264 |
| FAM53C | family with sequence similarity 53, member C | 0.00622867 |
| LOXL2 | lysyl oxidase-like 2 | 0.00620316 |
| AVIL | advillin | 0.00619748 |
| FBXO41 | F-box protein 41 | 0.0061737 |
| PPL | periplakin | 0.00614195 |
| CCNYL1 | cyclin Y-like 1 | 0.0061396 |
| PRKCA | protein kinase C, alpha | 0.00612506 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00612302 |
| HOXA3 | homeobox A3 | 0.00609521 |
| SLC45A4 | solute carrier family 45, member 4 | 0.00607699 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00606357 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00597064 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B | 0.00596336 |
| SEC24C | SEC24 family member C | 0.0059465 |
| PRX | periaxin | 0.00593607 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 0.00589641 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.00587607 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00583831 |
| BCORL1 | BCL6 corepressor-like 1 | 0.00575094 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.0057492 |
| EDC3 | enhancer of mRNA decapping 3 | 0.00574318 |
| RELT | RELT tumor necrosis factor receptor | 0.00568453 |
| SGSM3 | small G protein signaling modulator 3 | 0.00564948 |
| CCAR2 | cell cycle and apoptosis regulator 2 | 0.00562497 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00561954 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00560723 |
| MED26 | mediator complex subunit 26 | 0.00559297 |
| CACHD1 | cache domain containing 1 | 0.00557515 |
| RBM19 | RNA binding motif protein 19 | 0.0055631 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.00555046 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00554895 |
| EPPK1 | epiplakin 1 | 0.00554547 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.00552711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.259207 |
| PTMA | prothymosin, alpha | -0.246543 |
| AHNAK | AHNAK nucleoprotein | -0.163248 |
| FAT1 | FAT atypical cadherin 1 | -0.110889 |
| TMSB10 | thymosin beta 10 | -0.101716 |
| ENO1 | enolase 1, (alpha) | -0.0906538 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0736424 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0662185 |
| MKI67 | marker of proliferation Ki-67 | -0.064845 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.062272 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0591168 |
| UBC | ubiquitin C | -0.057538 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0534684 |
| KRT8 | keratin 8, type II | -0.0534679 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0533415 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.051955 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.048331 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0447154 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.043969 |
| RPS27A | ribosomal protein S27a | -0.0437607 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0435965 |
| PCBP2 | poly(rC) binding protein 2 | -0.0431417 |
| PKM | pyruvate kinase, muscle | -0.0424066 |
| TPM4 | tropomyosin 4 | -0.0411386 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0406218 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0398624 |
| LDHA | lactate dehydrogenase A | -0.0391494 |
| HMGB2 | high mobility group box 2 | -0.0390572 |
| PGK1 | phosphoglycerate kinase 1 | -0.0388178 |
| NF1 | neurofibromin 1 | -0.0381909 |
| CANX | calnexin | -0.0380478 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0369349 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0367255 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0364571 |
| S100A10 | S100 calcium binding protein A10 | -0.0356976 |
| ZNF292 | zinc finger protein 292 | -0.0354752 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0336528 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0335799 |
| CENPF | centromere protein F, 350/400kDa | -0.0331081 |
| TXNRD1 | thioredoxin reductase 1 | -0.0328704 |
| TUBA1B | tubulin, alpha 1b | -0.0328243 |
| RPS8 | ribosomal protein S8 | -0.0326358 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0321801 |
| RPS6 | ribosomal protein S6 | -0.0321297 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0319612 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0317228 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0313511 |
| DIAPH3 | diaphanous-related formin 3 | -0.031338 |
| MED13L | mediator complex subunit 13-like | -0.0313051 |
| ASPH | aspartate beta-hydroxylase | -0.0309775 |
| EPCAM | epithelial cell adhesion molecule | -0.0309133 |
| POTEF | POTE ankyrin domain family, member F | -0.0306639 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0303015 |
| GOLGA4 | golgin A4 | -0.0300546 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0298037 |
| RPS24 | ribosomal protein S24 | -0.0296257 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0288194 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0286576 |
| KRT18 | keratin 18, type I | -0.0284903 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.028236 |
| CD2AP | CD2-associated protein | -0.0280877 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0278889 |
| RAD51B | RAD51 paralog B | -0.0277405 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0277342 |
| OGA | O-GlcNAcase | -0.0276586 |
| RPL23 | ribosomal protein L23 | -0.0275574 |
| PERP | PERP, TP53 apoptosis effector | -0.0273082 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0266887 |
| XPO1 | exportin 1 | -0.0266383 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0263483 |
| RBM39 | RNA binding motif protein 39 | -0.026249 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0258277 |
| S100A9 | S100 calcium binding protein A9 | -0.0257409 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0253295 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0252401 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0252325 |
| HMGB1 | high mobility group box 1 | -0.0251351 |
| MT2A | metallothionein 2A | -0.025015 |
| EZR | ezrin | -0.0249934 |
| SERINC5 | serine incorporator 5 | -0.0245752 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0240125 |
| MSI2 | musashi RNA-binding protein 2 | -0.0239974 |
| SETD5 | SET domain containing 5 | -0.0235397 |
| TENM3 | teneurin transmembrane protein 3 | -0.0234378 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0233267 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0231079 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0230969 |
| RBM25 | RNA binding motif protein 25 | -0.0229963 |
| FHIT | fragile histidine triad | -0.0229186 |
| CBX3 | chromobox homolog 3 | -0.0228752 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0228112 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.022796 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.022739 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0227361 |
| ANLN | anillin, actin binding protein | -0.0227101 |
| GLG1 | golgi glycoprotein 1 | -0.0226815 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0226773 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0224442 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0224224 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0224029 |
