| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the NVP-BHG712_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.09549 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0893884 |
| PLEC | plectin | 0.0861969 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0546576 |
| NDRG1 | N-myc downstream regulated 1 | 0.0508723 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0503742 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0497161 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0484927 |
| CD44 | CD44 molecule (Indian blood group) | 0.0454973 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0426201 |
| SEPTIN9 | septin 9 | 0.0425339 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0415997 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0415074 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0377598 |
| FLNA | filamin A, alpha | 0.0374948 |
| ENO1 | enolase 1, (alpha) | 0.0368196 |
| LDHA | lactate dehydrogenase A | 0.0357207 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0348249 |
| COL5A1 | collagen, type V, alpha 1 | 0.0347896 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0340758 |
| RPS3 | ribosomal protein S3 | 0.0339566 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0326353 |
| MCL1 | myeloid cell leukemia 1 | 0.0315113 |
| ANGPTL4 | angiopoietin-like 4 | 0.0291706 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0287642 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0282667 |
| RPL12 | ribosomal protein L12 | 0.028107 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0274121 |
| TPI1 | triosephosphate isomerase 1 | 0.0272799 |
| RPL37A | ribosomal protein L37a | 0.026958 |
| RPS17 | ribosomal protein S17 | 0.026846 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0266969 |
| MSN | moesin | 0.025916 |
| RPS12 | ribosomal protein S12 | 0.0251111 |
| DST | dystonin | 0.0241482 |
| RPS4X | ribosomal protein S4, X-linked | 0.0240212 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0237338 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0233898 |
| TPM3 | tropomyosin 3 | 0.0221887 |
| VCL | vinculin | 0.0219004 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.021867 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0218595 |
| RPL3 | ribosomal protein L3 | 0.0216834 |
| PRELID2 | PRELI domain containing 2 | 0.021562 |
| RPS19 | ribosomal protein S19 | 0.0212878 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0212818 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0208915 |
| NAV1 | neuron navigator 1 | 0.0206684 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0205174 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0203734 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0202384 |
| RPL23 | ribosomal protein L23 | 0.0200315 |
| RPL7 | ribosomal protein L7 | 0.019834 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0197752 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0196165 |
| VEGFA | vascular endothelial growth factor A | 0.019285 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0192087 |
| RACK1 | receptor for activated C kinase 1 | 0.018598 |
| ATXN1 | ataxin 1 | 0.0183102 |
| RPS8 | ribosomal protein S8 | 0.0182518 |
| RPL9 | ribosomal protein L9 | 0.0181213 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0178752 |
| ACTN1 | actinin, alpha 1 | 0.017788 |
| RPL31 | ribosomal protein L31 | 0.0177572 |
| CAPRIN2 | caprin family member 2 | 0.0177456 |
| MLPH | melanophilin | 0.0174221 |
| EGFR | epidermal growth factor receptor | 0.017343 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0169691 |
| ACTG1 | actin gamma 1 | 0.0165091 |
| INTS6 | integrator complex subunit 6 | 0.0164819 |
| B2M | beta-2-microglobulin | 0.0162151 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0162055 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0156303 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0155934 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0155721 |
| MT1E | metallothionein 1E | 0.0155047 |
| TNS1 | tensin 1 | 0.0154747 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0154266 |
| RPL35A | ribosomal protein L35a | 0.0153618 |
| PDLIM4 | PDZ and LIM domain 4 | 0.0153416 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0150974 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0148637 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0148319 |
| RCOR1 | REST corepressor 1 | 0.0148045 |
| RPL19 | ribosomal protein L19 | 0.0147349 |
| PODXL | podocalyxin-like | 0.0147132 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0145732 |
| WWOX | WW domain containing oxidoreductase | 0.0140878 |
| HMGA2 | high mobility group AT-hook 2 | 0.0140744 |
| RPL11 | ribosomal protein L11 | 0.0140205 |
| AHNAK | AHNAK nucleoprotein | 0.014012 |
| HLA-C | major histocompatibility complex, class I, C | 0.0139732 |
| ANXA2 | annexin A2 | 0.0139639 |
| DSPP | dentin sialophosphoprotein | 0.0138921 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0138357 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0134934 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0129402 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0128449 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0122961 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0122882 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.363375 |
| VIM | vimentin | -0.136118 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.07118 |
| PTMA | prothymosin, alpha | -0.0542131 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0510457 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0495683 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0404092 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0403393 |
| CDH13 | cadherin 13 | -0.0374144 |
| RLF | rearranged L-myc fusion | -0.0349068 |
| FAM13A | family with sequence similarity 13, member A | -0.03472 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0321812 |
| SETD5 | SET domain containing 5 | -0.0319709 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0319704 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0312138 |
| IER3 | immediate early response 3 | -0.0301388 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0298325 |
| ZNF292 | zinc finger protein 292 | -0.0288835 |
| CLMP | CXADR-like membrane protein | -0.0281852 |
| SPAG9 | sperm associated antigen 9 | -0.0281205 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0279191 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0275765 |
| USP3 | ubiquitin specific peptidase 3 | -0.0269692 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0262774 |
| SEC24A | SEC24 family member A | -0.0253424 |
| GNAS | GNAS complex locus | -0.0242785 |
| GOLGA4 | golgin A4 | -0.0241688 |
| OGA | O-GlcNAcase | -0.0238176 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0236815 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0235332 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0234017 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0233832 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0232919 |
| RBM39 | RNA binding motif protein 39 | -0.023094 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.022797 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0225651 |
| COL1A1 | collagen, type I, alpha 1 | -0.0225308 |
| RAI14 | retinoic acid induced 14 | -0.0225164 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0222916 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0219773 |
| LOX | lysyl oxidase | -0.0219684 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0219135 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0216828 |
| QKI | QKI, KH domain containing, RNA binding | -0.0211908 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0209536 |
| HELZ | helicase with zinc finger | -0.0208676 |
| STC1 | stanniocalcin 1 | -0.0208131 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0207615 |
| CDCP1 | CUB domain containing protein 1 | -0.0205958 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0205331 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0204536 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0204458 |
| NGLY1 | N-glycanase 1 | -0.0203617 |
| CANX | calnexin | -0.0199324 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0199002 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0195431 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0194892 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0187766 |
| RNF24 | ring finger protein 24 | -0.0186854 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0185785 |
| MORF4L2 | mortality factor 4 like 2 | -0.0185268 |
| GLG1 | golgi glycoprotein 1 | -0.0184832 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.018449 |
| SBF2 | SET binding factor 2 | -0.0181732 |
| RAD21 | RAD21 homolog (S. pombe) | -0.018132 |
| WASF2 | WAS protein family, member 2 | -0.0181057 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0180297 |
| INHBA | inhibin, beta A | -0.0177251 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0175932 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0174207 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0173471 |
| S100A10 | S100 calcium binding protein A10 | -0.0171741 |
| MMP12 | matrix metallopeptidase 12 | -0.0171215 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0167744 |
| TMEM165 | transmembrane protein 165 | -0.0167087 |
| WDR45B | WD repeat domain 45B | -0.0165718 |
| RRBP1 | ribosome binding protein 1 | -0.0165323 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0164273 |
| TUBB6 | tubulin, beta 6 class V | -0.0163953 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0163016 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0162933 |
| PTK2 | protein tyrosine kinase 2 | -0.0162234 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0161576 |
| ADM | adrenomedullin | -0.0158092 |
| TMEM263 | transmembrane protein 263 | -0.0157239 |
| MIS18BP1 | MIS18 binding protein 1 | -0.015626 |
| PGK1 | phosphoglycerate kinase 1 | -0.0156091 |
| RPS24 | ribosomal protein S24 | -0.0155858 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0155447 |
| NOP58 | NOP58 ribonucleoprotein | -0.0154615 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0154468 |
| TFG | TRK-fused gene | -0.0154308 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0153879 |
| IGF2 | insulin-like growth factor 2 | -0.0152914 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0151918 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0146764 |
| CCNI | cyclin I | -0.014669 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0146192 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0145668 |
| FUS | FUS RNA binding protein | -0.0143646 |
