| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | 0.125468 |
| KRT20 | keratin 20, type I | 0.0921239 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0840725 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0786521 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0708508 |
| NDRG1 | N-myc downstream regulated 1 | 0.0653466 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0609323 |
| RPS3 | ribosomal protein S3 | 0.0605073 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0554691 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0514051 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.044177 |
| RPS12 | ribosomal protein S12 | 0.0438371 |
| ACTG1 | actin gamma 1 | 0.0437166 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0435337 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0428344 |
| FRY | furry homolog (Drosophila) | 0.0421645 |
| LMO7 | LIM domain 7 | 0.0419045 |
| POF1B | premature ovarian failure, 1B | 0.0408713 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0389517 |
| RNF213 | ring finger protein 213 | 0.0380726 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.037815 |
| KRT18 | keratin 18, type I | 0.0376859 |
| TRIB1 | tribbles pseudokinase 1 | 0.0376663 |
| AHNAK | AHNAK nucleoprotein | 0.0367941 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0360119 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0359122 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0357485 |
| JUN | jun proto-oncogene | 0.034537 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0343124 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0340476 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0321831 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0312213 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0303653 |
| INTS6 | integrator complex subunit 6 | 0.0302348 |
| DIAPH2 | diaphanous-related formin 2 | 0.0301634 |
| TLE4 | transducin-like enhancer of split 4 | 0.0295604 |
| KRT19 | keratin 19, type I | 0.0286328 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0285022 |
| DST | dystonin | 0.0282018 |
| RASEF | RAS and EF-hand domain containing | 0.0277596 |
| B2M | beta-2-microglobulin | 0.0272932 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0262663 |
| VEGFA | vascular endothelial growth factor A | 0.0261351 |
| MMP7 | matrix metallopeptidase 7 | 0.0260448 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0259546 |
| PRR5L | proline rich 5 like | 0.0255857 |
| PRELID2 | PRELI domain containing 2 | 0.0255287 |
| GOLGB1 | golgin B1 | 0.0253711 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0253243 |
| EXPH5 | exophilin 5 | 0.0244604 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0244296 |
| TJP1 | tight junction protein 1 | 0.0243036 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0241189 |
| LMNA | lamin A/C | 0.0238927 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.023826 |
| FOXP1 | forkhead box P1 | 0.023042 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0226931 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0226762 |
| ANXA4 | annexin A4 | 0.0225667 |
| ETV6 | ets variant 6 | 0.0224387 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0222383 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0216008 |
| RIGI | RNA sensor RIG-I | 0.0214024 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0208379 |
| GSN | gelsolin | 0.0207426 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.020713 |
| CLDN4 | claudin 4 | 0.0206116 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0204997 |
| BPTF | bromodomain PHD finger transcription factor | 0.0202679 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0202356 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0199671 |
| PGK1 | phosphoglycerate kinase 1 | 0.0197852 |
| PKM | pyruvate kinase, muscle | 0.0196025 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0194903 |
| FAT1 | FAT atypical cadherin 1 | 0.0194774 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0193749 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0193562 |
| EZR | ezrin | 0.0191249 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0190681 |
| DSPP | dentin sialophosphoprotein | 0.0190157 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0188445 |
| PLK2 | polo-like kinase 2 | 0.0186831 |
| PLEC | plectin | 0.0185753 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0179823 |
| PCED1B | PC-esterase domain containing 1B | 0.0177513 |
| RACK1 | receptor for activated C kinase 1 | 0.0176386 |
| EXOC4 | exocyst complex component 4 | 0.0176236 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0175233 |
| MYO5B | myosin VB | 0.0174385 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0173501 |
| LDHA | lactate dehydrogenase A | 0.0173226 |
| TPI1 | triosephosphate isomerase 1 | 0.0171676 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0171051 |
| MYADM | myeloid-associated differentiation marker | 0.0169407 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0168507 |
| HSPA8 | heat shock 70kDa protein 8 | 0.016763 |
| UTRN | utrophin | 0.0166648 |
| RAD51B | RAD51 paralog B | 0.0165717 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 0.0164555 |
| TMC5 | transmembrane channel-like 5 | 0.0164226 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.158286 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.157419 |
| TXNRD1 | thioredoxin reductase 1 | -0.124466 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101318 |
| RPLP1 | ribosomal protein, large, P1 | -0.0888405 |
| RPLP2 | ribosomal protein, large, P2 | -0.0665366 |
| FTL | ferritin, light polypeptide | -0.0648062 |
| RPL23 | ribosomal protein L23 | -0.0621836 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0608756 |
| RPS11 | ribosomal protein S11 | -0.0608407 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0534761 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0523844 |
| RPS16 | ribosomal protein S16 | -0.0517398 |
| RPS24 | ribosomal protein S24 | -0.0502605 |
| RPS6 | ribosomal protein S6 | -0.0501911 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.047184 |
| RPS19 | ribosomal protein S19 | -0.0469185 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0464783 |
| RPS23 | ribosomal protein S23 | -0.0464065 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0441605 |
| ACTN4 | actinin, alpha 4 | -0.0431642 |
| RPL28 | ribosomal protein L28 | -0.0430955 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0427159 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0420197 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413912 |
| CANX | calnexin | -0.04128 |
| RBM39 | RNA binding motif protein 39 | -0.0396531 |
| TMSB10 | thymosin beta 10 | -0.0391416 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0379071 |
| STK24 | serine/threonine kinase 24 | -0.0373942 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0373228 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0365194 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0357221 |
| RPS5 | ribosomal protein S5 | -0.0346479 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0345354 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.03385 |
| BCL2L1 | BCL2-like 1 | -0.033824 |
| GOLGA4 | golgin A4 | -0.0336129 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.033506 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0334201 |
| RPL32 | ribosomal protein L32 | -0.0333128 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0328308 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0324822 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0321407 |
| RHEB | Ras homolog enriched in brain | -0.031916 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0317562 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0315331 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0309983 |
| VMP1 | vacuole membrane protein 1 | -0.0309828 |
| WASF2 | WAS protein family, member 2 | -0.0301445 |
| RPL8 | ribosomal protein L8 | -0.0299779 |
| RPL36A | ribosomal protein L36a | -0.0298913 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0287008 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0286517 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0278641 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0277402 |
| HMGB1 | high mobility group box 1 | -0.0275124 |
| SBF2 | SET binding factor 2 | -0.0269496 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0266446 |
| RPS15 | ribosomal protein S15 | -0.0265279 |
| COG5 | component of oligomeric golgi complex 5 | -0.0261371 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0258912 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0257696 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0256596 |
| RPS21 | ribosomal protein S21 | -0.0253588 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0251558 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0250647 |
| JMJD1C | jumonji domain containing 1C | -0.0248726 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0246479 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0243119 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0241208 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0241102 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0239726 |
| CALR | calreticulin | -0.0239446 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0238076 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0237621 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0237235 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0235073 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0233317 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0232284 |
| HM13 | histocompatibility (minor) 13 | -0.0231739 |
| CCNL1 | cyclin L1 | -0.023107 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0228061 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0226594 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0226482 |
| RPS25 | ribosomal protein S25 | -0.022314 |
| CCNI | cyclin I | -0.0222973 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0222442 |
| WWC1 | WW and C2 domain containing 1 | -0.0222362 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.022218 |
| RLF | rearranged L-myc fusion | -0.0220099 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0220056 |
| TMEM41B | transmembrane protein 41B | -0.021996 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0219651 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0214696 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.021331 |
| NUP58 | nucleoporin 58 | -0.0211993 |
| ANXA11 | annexin A11 | -0.0211608 |
| OGA | O-GlcNAcase | -0.0211523 |
| RTN4 | reticulon 4 | -0.0211283 |
