| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.163061 |
| FN1 | fibronectin 1 | 0.156905 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.143858 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0984975 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0909276 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0892556 |
| NDRG1 | N-myc downstream regulated 1 | 0.0873933 |
| MT2A | metallothionein 2A | 0.0841427 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0616061 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0605042 |
| LDHA | lactate dehydrogenase A | 0.0597594 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0597502 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0597383 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0587743 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0573769 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0533669 |
| FLNA | filamin A, alpha | 0.0530838 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0499651 |
| INTS6 | integrator complex subunit 6 | 0.0495857 |
| ENO1 | enolase 1, (alpha) | 0.0485896 |
| POTEF | POTE ankyrin domain family, member F | 0.0472337 |
| ACTG1 | actin gamma 1 | 0.0464542 |
| NAV2 | neuron navigator 2 | 0.0463738 |
| ASPH | aspartate beta-hydroxylase | 0.0462428 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0455463 |
| ANXA2 | annexin A2 | 0.0453681 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0449638 |
| PODXL | podocalyxin-like | 0.0435515 |
| CD44 | CD44 molecule (Indian blood group) | 0.0410429 |
| ACTN1 | actinin, alpha 1 | 0.0408626 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0405241 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0385786 |
| TLE4 | transducin-like enhancer of split 4 | 0.0360451 |
| COL5A1 | collagen, type V, alpha 1 | 0.0352511 |
| HLA-C | major histocompatibility complex, class I, C | 0.0351608 |
| FLNB | filamin B, beta | 0.0350669 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0346523 |
| MSN | moesin | 0.0346352 |
| DTNA | dystrobrevin, alpha | 0.0344024 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0335874 |
| TPM3 | tropomyosin 3 | 0.0330352 |
| EGFR | epidermal growth factor receptor | 0.0322765 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0322448 |
| VCL | vinculin | 0.0319728 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0313921 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0309525 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0303072 |
| PLEC | plectin | 0.0300469 |
| RNF213 | ring finger protein 213 | 0.0293661 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0287913 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0286416 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0285728 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0284223 |
| ERBIN | erbb2 interacting protein | 0.0282297 |
| VEGFA | vascular endothelial growth factor A | 0.0278807 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.027663 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0275556 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0274723 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0273782 |
| MCL1 | myeloid cell leukemia 1 | 0.0270207 |
| VIM | vimentin | 0.0268518 |
| NAV1 | neuron navigator 1 | 0.026583 |
| RUNX1 | runt-related transcription factor 1 | 0.0261106 |
| PKM | pyruvate kinase, muscle | 0.0260898 |
| KRT7 | keratin 7, type II | 0.025647 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0254762 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0254145 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0252582 |
| STC2 | stanniocalcin 2 | 0.0250548 |
| ZNF841 | zinc finger protein 841 | 0.0248009 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.024738 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0246135 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0243088 |
| RAD51B | RAD51 paralog B | 0.0241563 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0241481 |
| ATXN1 | ataxin 1 | 0.0241074 |
| RPS3 | ribosomal protein S3 | 0.024068 |
| RPS17 | ribosomal protein S17 | 0.0240216 |
| RPS6 | ribosomal protein S6 | 0.0234929 |
| ZNF432 | zinc finger protein 432 | 0.0233423 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0231897 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0231857 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0230687 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0230454 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0230085 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0229682 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0226886 |
| SET | SET nuclear proto-oncogene | 0.022603 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0225225 |
| CCND1 | cyclin D1 | 0.0223974 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0221824 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0220933 |
| PLSCR1 | phospholipid scramblase 1 | 0.0220162 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0219762 |
| RACK1 | receptor for activated C kinase 1 | 0.021751 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0217247 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0214442 |
| SEPTIN9 | septin 9 | 0.0213189 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0212895 |
| CALD1 | caldesmon 1 | 0.0212154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.0878355 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0847029 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0650943 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0568518 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0552707 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0439123 |
| ATP13A3 | ATPase type 13A3 | -0.0401324 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0380118 |
| MT1X | metallothionein 1X | -0.0367741 |
| GOLGA4 | golgin A4 | -0.0346696 |
| FTL | ferritin, light polypeptide | -0.0335173 |
| PTMA | prothymosin, alpha | -0.0318576 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0279732 |
| ARF4 | ADP-ribosylation factor 4 | -0.0263314 |
| TXNRD1 | thioredoxin reductase 1 | -0.0262639 |
| RLF | rearranged L-myc fusion | -0.0261708 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0259959 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0255119 |
| USP3 | ubiquitin specific peptidase 3 | -0.0250543 |
| ZNF292 | zinc finger protein 292 | -0.0249009 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0242502 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0239605 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0234128 |
| TPD52 | tumor protein D52 | -0.0232978 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.023098 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0230037 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0228267 |
| ZFR | zinc finger RNA binding protein | -0.0225961 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0223851 |
| SUCO | SUN domain containing ossification factor | -0.021058 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0210351 |
| POSTN | periostin, osteoblast specific factor | -0.020565 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0203931 |
| GOLT1B | golgi transport 1B | -0.0202619 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0195613 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0194833 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0191846 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0191519 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0191157 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0190834 |
| HMGB1 | high mobility group box 1 | -0.0189937 |
| DEK | DEK proto-oncogene | -0.0188065 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0186112 |
| S100A10 | S100 calcium binding protein A10 | -0.0182862 |
| SRP54 | signal recognition particle 54kDa | -0.0181148 |
| NOP58 | NOP58 ribonucleoprotein | -0.0179372 |
| SPAG9 | sperm associated antigen 9 | -0.0178188 |
| NUP153 | nucleoporin 153kDa | -0.0177081 |
| RBM39 | RNA binding motif protein 39 | -0.0176693 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.017209 |
| TMEM41B | transmembrane protein 41B | -0.0169335 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0168533 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0166912 |
| NUP58 | nucleoporin 58 | -0.0164489 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0164237 |
| DENND4C | DENN/MADD domain containing 4C | -0.0163792 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0163668 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0160264 |
| TGFB2 | transforming growth factor, beta 2 | -0.0157319 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0153168 |
| TFG | TRK-fused gene | -0.0152839 |
| IER3 | immediate early response 3 | -0.0152613 |
| SETD5 | SET domain containing 5 | -0.0152097 |
| TNPO1 | transportin 1 | -0.0151647 |
| CTSD | cathepsin D | -0.0151368 |
| RHEB | Ras homolog enriched in brain | -0.0151291 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0151282 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0150549 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0149269 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0148496 |
| PDS5B | PDS5 cohesin associated factor B | -0.0147516 |
| H1-0 | H1.0 linker histone | -0.0146521 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.014592 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.0145497 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0145223 |
| SEPTIN7 | septin 7 | -0.0145055 |
| SULF1 | sulfatase 1 | -0.0142949 |
| SCFD2 | sec1 family domain containing 2 | -0.0142716 |
| COG5 | component of oligomeric golgi complex 5 | -0.0140418 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0140168 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0139335 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0138823 |
| QKI | QKI, KH domain containing, RNA binding | -0.0137896 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0137566 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0137249 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0136422 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0135703 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0135439 |
| HMGB2 | high mobility group box 2 | -0.0134861 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.0134161 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0133922 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0133756 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0133579 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0133187 |
| SNX4 | sorting nexin 4 | -0.0132929 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0132533 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0131313 |
| WTAP | Wilms tumor 1 associated protein | -0.0131118 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0130899 |
| MPZL1 | myelin protein zero-like 1 | -0.0130867 |
