| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the NVP-BHG712_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0903837 |
| RUNX1 | runt-related transcription factor 1 | 0.0732009 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0591591 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0573069 |
| PODXL | podocalyxin-like | 0.0561054 |
| CAPRIN2 | caprin family member 2 | 0.0549014 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0516759 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0499026 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0457662 |
| RPS12 | ribosomal protein S12 | 0.0424312 |
| PLEC | plectin | 0.0393165 |
| EZR | ezrin | 0.0390768 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0390182 |
| CD44 | CD44 molecule (Indian blood group) | 0.0366507 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0360361 |
| ACTG1 | actin gamma 1 | 0.0341543 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0310973 |
| DST | dystonin | 0.0307634 |
| ANXA2 | annexin A2 | 0.0302534 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0297855 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0295707 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0294921 |
| WDR27 | WD repeat domain 27 | 0.0287559 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0282608 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0280082 |
| RPS3 | ribosomal protein S3 | 0.0265005 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0263099 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0260953 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0255911 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0248532 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.024521 |
| INTS6 | integrator complex subunit 6 | 0.0242117 |
| RACK1 | receptor for activated C kinase 1 | 0.0240095 |
| CEP250 | centrosomal protein 250kDa | 0.0232767 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0230701 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0228444 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.022535 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0224774 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0220729 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0219427 |
| SEPTIN9 | septin 9 | 0.0216966 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0212763 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0212373 |
| MCL1 | myeloid cell leukemia 1 | 0.0209511 |
| RNF213 | ring finger protein 213 | 0.0208219 |
| ASPH | aspartate beta-hydroxylase | 0.0203663 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0202992 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.020278 |
| HLA-C | major histocompatibility complex, class I, C | 0.0197691 |
| CMIP | c-Maf inducing protein | 0.0196711 |
| EGR1 | early growth response 1 | 0.0196684 |
| JUN | jun proto-oncogene | 0.0193439 |
| RPL3 | ribosomal protein L3 | 0.0192949 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.019102 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.01884 |
| HOMER1 | homer scaffolding protein 1 | 0.0187664 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0187082 |
| ACTN1 | actinin, alpha 1 | 0.0184652 |
| RPL37A | ribosomal protein L37a | 0.0182686 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0181965 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0181597 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0177447 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0176401 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0171291 |
| NDRG1 | N-myc downstream regulated 1 | 0.017108 |
| AHNAK | AHNAK nucleoprotein | 0.0170324 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0169557 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0168626 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0168074 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0167879 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0166293 |
| ANGPTL4 | angiopoietin-like 4 | 0.0163768 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0162357 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0162264 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0162245 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0161794 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0160551 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0157913 |
| EMP1 | epithelial membrane protein 1 | 0.0156358 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0152382 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0151562 |
| RCOR1 | REST corepressor 1 | 0.0148821 |
| MLPH | melanophilin | 0.0147047 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0142715 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0142692 |
| RAD51B | RAD51 paralog B | 0.0142341 |
| F2R | coagulation factor II (thrombin) receptor | 0.0142145 |
| BPTF | bromodomain PHD finger transcription factor | 0.014194 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0141679 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0141567 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0140606 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0140376 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0139363 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0138671 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0137879 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0137439 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0136981 |
| ZNF638 | zinc finger protein 638 | 0.0134526 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0133772 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0131746 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.392792 |
| PTMA | prothymosin, alpha | -0.206435 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.185186 |
| TMSB10 | thymosin beta 10 | -0.144024 |
| VIM | vimentin | -0.1293 |
| TMSB4X | thymosin beta 4, X-linked | -0.0944969 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0934196 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0772813 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0769818 |
| HLA-B | major histocompatibility complex, class I, B | -0.0759741 |
| SRGN | serglycin | -0.0686146 |
| TP63 | tumor protein p63 | -0.0607652 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.059246 |
| MT2A | metallothionein 2A | -0.0589553 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0540817 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.053222 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0527895 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0515083 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0492258 |
| RPS24 | ribosomal protein S24 | -0.0472649 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.04447 |
| CANX | calnexin | -0.0444024 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.044315 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0436832 |
| RAI1 | retinoic acid induced 1 | -0.0400629 |
| ZNF217 | zinc finger protein 217 | -0.0393776 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0386279 |
| MT1X | metallothionein 1X | -0.0379423 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0375747 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0372556 |
| TMEM123 | transmembrane protein 123 | -0.0369352 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0343985 |
| POTEF | POTE ankyrin domain family, member F | -0.0340958 |
| PGK1 | phosphoglycerate kinase 1 | -0.0340091 |
| RPL32 | ribosomal protein L32 | -0.0336184 |
| RPS23 | ribosomal protein S23 | -0.0335219 |
| RPS19 | ribosomal protein S19 | -0.0335002 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0333031 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0330523 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0327139 |
| SRPK2 | SRSF protein kinase 2 | -0.0325806 |
| SETD5 | SET domain containing 5 | -0.0325645 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0322703 |
| FUS | FUS RNA binding protein | -0.0320556 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0318294 |
| RBM25 | RNA binding motif protein 25 | -0.0316303 |
| RPS6 | ribosomal protein S6 | -0.031523 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0313177 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0308771 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0308376 |
| KLF6 | Kruppel-like factor 6 | -0.0306385 |
| RPLP2 | ribosomal protein, large, P2 | -0.0303001 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0301945 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0301424 |
| RBM39 | RNA binding motif protein 39 | -0.0300908 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0299288 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0288196 |
| RPL8 | ribosomal protein L8 | -0.0285519 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0282579 |
| CENPF | centromere protein F, 350/400kDa | -0.0278922 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0277843 |
| RPL12 | ribosomal protein L12 | -0.0273668 |
| UBC | ubiquitin C | -0.0272881 |
| GNAS | GNAS complex locus | -0.0270484 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0262522 |
| NOP58 | NOP58 ribonucleoprotein | -0.0262069 |
| OGA | O-GlcNAcase | -0.0253517 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0251407 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0251316 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0248186 |
| ZNF292 | zinc finger protein 292 | -0.0246621 |
| EHBP1 | EH domain binding protein 1 | -0.0245395 |
| EFNA5 | ephrin-A5 | -0.0243893 |
| TXNIP | thioredoxin interacting protein | -0.0243579 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0242111 |
| RPL36A | ribosomal protein L36a | -0.0241942 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0239753 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.023925 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0238842 |
| ZFR | zinc finger RNA binding protein | -0.0238225 |
| RPS15 | ribosomal protein S15 | -0.0237914 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0235142 |
| KLHL24 | kelch-like family member 24 | -0.0234826 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0230968 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0229753 |
| KHSRP | KH-type splicing regulatory protein | -0.0228675 |
| ANLN | anillin, actin binding protein | -0.0226405 |
| S100A9 | S100 calcium binding protein A9 | -0.0225969 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0225859 |
| TOP1 | topoisomerase (DNA) I | -0.0225039 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0222882 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0222745 |
| CBX3 | chromobox homolog 3 | -0.0222242 |
| PFN1 | profilin 1 | -0.022217 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0221511 |
| VMP1 | vacuole membrane protein 1 | -0.022127 |
| S100A10 | S100 calcium binding protein A10 | -0.0216939 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0215855 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0215164 |
| RPS21 | ribosomal protein S21 | -0.0214953 |
