| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the NVP-BHG712_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0592876 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0513973 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0411285 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0398124 |
| RPS19 | ribosomal protein S19 | 0.0378688 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0371707 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0354369 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0348322 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0315759 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0312616 |
| INTS6 | integrator complex subunit 6 | 0.0311269 |
| RPL36 | ribosomal protein L36 | 0.0310024 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0309785 |
| IFI44L | interferon-induced protein 44-like | 0.0304338 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0303538 |
| RPS12 | ribosomal protein S12 | 0.030038 |
| AADAC | arylacetamide deacetylase | 0.0298631 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0281919 |
| ANGPTL4 | angiopoietin-like 4 | 0.0272091 |
| VEGFA | vascular endothelial growth factor A | 0.0271835 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0268032 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0264919 |
| RPS17 | ribosomal protein S17 | 0.025432 |
| MT2A | metallothionein 2A | 0.0252609 |
| RPS3 | ribosomal protein S3 | 0.0250265 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0243315 |
| NAV2 | neuron navigator 2 | 0.0228987 |
| ATXN1 | ataxin 1 | 0.022235 |
| FTL | ferritin, light polypeptide | 0.020966 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0209195 |
| RPL35A | ribosomal protein L35a | 0.0207977 |
| RACK1 | receptor for activated C kinase 1 | 0.0205852 |
| FN1 | fibronectin 1 | 0.0205533 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.020273 |
| SMAD3 | SMAD family member 3 | 0.0201134 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0196604 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0191757 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0190753 |
| CEP250 | centrosomal protein 250kDa | 0.0184973 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0184232 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.017813 |
| B2M | beta-2-microglobulin | 0.0176651 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0172737 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0171985 |
| LOXL2 | lysyl oxidase-like 2 | 0.0171943 |
| RPL11 | ribosomal protein L11 | 0.017119 |
| RAD51B | RAD51 paralog B | 0.017078 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0166665 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0164205 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0162176 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0162021 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0158624 |
| RPL37 | ribosomal protein L37 | 0.0158407 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0153544 |
| RPL37A | ribosomal protein L37a | 0.0149043 |
| NLK | nemo-like kinase | 0.0148594 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0146776 |
| RPL31 | ribosomal protein L31 | 0.0146441 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0143591 |
| RPL3 | ribosomal protein L3 | 0.0136634 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0136399 |
| LMNA | lamin A/C | 0.0136082 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0134698 |
| RPL19 | ribosomal protein L19 | 0.0133774 |
| RPL18 | ribosomal protein L18 | 0.0133262 |
| RNF213 | ring finger protein 213 | 0.0130967 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0130908 |
| SEPTIN9 | septin 9 | 0.0130057 |
| ASPH | aspartate beta-hydroxylase | 0.0128097 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.012591 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0125665 |
| ZNF469 | zinc finger protein 469 | 0.0125019 |
| RPS13 | ribosomal protein S13 | 0.0123111 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0123099 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0122148 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0122086 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0121393 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0120096 |
| RPS4X | ribosomal protein S4, X-linked | 0.0118772 |
| FAM219A | family with sequence similarity 219, member A | 0.0117638 |
| RPL27 | ribosomal protein L27 | 0.0116855 |
| TPI1 | triosephosphate isomerase 1 | 0.0116384 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0114919 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0113718 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0112937 |
| ZNF638 | zinc finger protein 638 | 0.0112409 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0111455 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0111325 |
| MCL1 | myeloid cell leukemia 1 | 0.011128 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0110908 |
| ATP5MC2 | ATP synthase membrane subunit c locus 2 | 0.0110897 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0110358 |
| HLA-C | major histocompatibility complex, class I, C | 0.0108186 |
| TGFB1 | transforming growth factor, beta 1 | 0.0107522 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0106635 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0106514 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0106191 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0105985 |
| IFI44 | interferon-induced protein 44 | 0.010449 |
| RPS6 | ribosomal protein S6 | 0.0104396 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164282 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.162832 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0917772 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0861181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0743808 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0634304 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0612501 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0594791 |
| VIM | vimentin | -0.0592787 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0583456 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0577265 |
| CD44 | CD44 molecule (Indian blood group) | -0.0574595 |
| OSMR | oncostatin M receptor | -0.0546421 |
| RBM39 | RNA binding motif protein 39 | -0.0545346 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0506483 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0496044 |
| UBC | ubiquitin C | -0.0493742 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0488721 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.048783 |
| NRP1 | neuropilin 1 | -0.0487745 |
| USP34 | ubiquitin specific peptidase 34 | -0.0462637 |
| GLCCI1 | glucocorticoid induced 1 | -0.0451628 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0449997 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0446436 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0435875 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0428864 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0419101 |
| GOLGA4 | golgin A4 | -0.0415689 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.04034 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0395888 |
| STC1 | stanniocalcin 1 | -0.0395334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0387772 |
| PTMA | prothymosin, alpha | -0.0386031 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0381552 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0371474 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0371319 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0362814 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0358597 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0358584 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0358146 |
| SETD5 | SET domain containing 5 | -0.0341054 |
| ATP13A3 | ATPase type 13A3 | -0.0337039 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0335938 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0335263 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0331272 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0325724 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0324894 |
| CANX | calnexin | -0.0320103 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0314363 |
| JMJD1C | jumonji domain containing 1C | -0.0307755 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0306765 |
| RAI14 | retinoic acid induced 14 | -0.0305404 |
| OGA | O-GlcNAcase | -0.0300745 |
| AHNAK | AHNAK nucleoprotein | -0.0298205 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0297328 |
| OXSR1 | oxidative stress responsive 1 | -0.0295861 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.029578 |
| DENND4A | DENN/MADD domain containing 4A | -0.0291875 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.029101 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0290593 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0290559 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0289559 |
| NRG1 | neuregulin 1 | -0.0283385 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0278087 |
| IER3 | immediate early response 3 | -0.0277821 |
| ETV6 | ets variant 6 | -0.0263146 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0260754 |
| NUMB | numb homolog (Drosophila) | -0.026002 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0259506 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0259281 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0258215 |
| SPAG9 | sperm associated antigen 9 | -0.0256954 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.025181 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0250922 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0248917 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0248758 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0247824 |
| PARD3 | par-3 family cell polarity regulator | -0.0246425 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0245296 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.024371 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0242935 |
| RNF24 | ring finger protein 24 | -0.0242679 |
| EREG | epiregulin | -0.0239645 |
| SSH2 | slingshot protein phosphatase 2 | -0.0238899 |
| TMEM263 | transmembrane protein 263 | -0.023724 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0230611 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0227834 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0227159 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0224662 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0223327 |
| SNX9 | sorting nexin 9 | -0.0222069 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0221481 |
| GLG1 | golgi glycoprotein 1 | -0.0218022 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0216872 |
| S100A10 | S100 calcium binding protein A10 | -0.0216645 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0214984 |
| BMERB1 | bMERB domain containing 1 | -0.0214902 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0211419 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0211109 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0210133 |
