| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.269582 |
| RPS16 | ribosomal protein S16 | 0.168494 |
| LOC112694756 | uncharaterized LOC112694756 | 0.12339 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.109023 |
| VIM | vimentin | 0.0983127 |
| MCL1 | myeloid cell leukemia 1 | 0.0854179 |
| EGR1 | early growth response 1 | 0.0834318 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0829816 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.07474 |
| MYO1E | myosin IE | 0.0746241 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0696111 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.067554 |
| RPL35A | ribosomal protein L35a | 0.0667006 |
| INTS6 | integrator complex subunit 6 | 0.0627253 |
| TMSB10 | thymosin beta 10 | 0.0621374 |
| RPLP1 | ribosomal protein, large, P1 | 0.0544576 |
| PLEC | plectin | 0.0512198 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0477278 |
| HMGA2 | high mobility group AT-hook 2 | 0.0460628 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0444427 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0410818 |
| NAV2 | neuron navigator 2 | 0.040666 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0383399 |
| RPS4X | ribosomal protein S4, X-linked | 0.0380468 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0380258 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0377558 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0370705 |
| RPLP0 | ribosomal protein, large, P0 | 0.0359516 |
| FLNA | filamin A, alpha | 0.0358258 |
| RPL37 | ribosomal protein L37 | 0.0355973 |
| SQSTM1 | sequestosome 1 | 0.0349826 |
| HDAC9 | histone deacetylase 9 | 0.0347804 |
| FBL | fibrillarin | 0.0339061 |
| AHNAK | AHNAK nucleoprotein | 0.0336841 |
| TPM1 | tropomyosin 1 (alpha) | 0.033315 |
| JUN | jun proto-oncogene | 0.0313742 |
| SFTPA2 | surfactant protein A2 | 0.0308964 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0306961 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0306217 |
| RPL23 | ribosomal protein L23 | 0.0306075 |
| RPS24 | ribosomal protein S24 | 0.0302921 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0302766 |
| HDLBP | high density lipoprotein binding protein | 0.030034 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0299222 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0298309 |
| CTSD | cathepsin D | 0.0297548 |
| RPL27A | ribosomal protein L27a | 0.029512 |
| NUP98 | nucleoporin 98kDa | 0.0294187 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0289474 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0285856 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0282115 |
| FHL2 | four and a half LIM domains 2 | 0.0281751 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0275833 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0274038 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0270753 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0270677 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.026602 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0259887 |
| EGFR | epidermal growth factor receptor | 0.0258693 |
| L1CAM | L1 cell adhesion molecule | 0.0257809 |
| MYO10 | myosin X | 0.0248277 |
| RPLP2 | ribosomal protein, large, P2 | 0.0245649 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0244699 |
| CMIP | c-Maf inducing protein | 0.0240123 |
| RPL34 | ribosomal protein L34 | 0.0239284 |
| SKI | SKI proto-oncogene | 0.0239257 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0238494 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0238015 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0231948 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0231916 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.023104 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0230646 |
| RPS20 | ribosomal protein S20 | 0.0229298 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0229138 |
| FTL | ferritin, light polypeptide | 0.0228672 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0227332 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0226077 |
| RPS8 | ribosomal protein S8 | 0.022135 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0221184 |
| RACK1 | receptor for activated C kinase 1 | 0.0220168 |
| SEPTIN9 | septin 9 | 0.0215189 |
| ACTN1 | actinin, alpha 1 | 0.0213693 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0213598 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0213218 |
| MED29 | mediator complex subunit 29 | 0.0212857 |
| KRT18 | keratin 18, type I | 0.0212404 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0208686 |
| RPS17 | ribosomal protein S17 | 0.020659 |
| CTBP2 | C-terminal binding protein 2 | 0.0205872 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0204386 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0204252 |
| ANGPTL4 | angiopoietin-like 4 | 0.0202194 |
| RSU1 | Ras suppressor protein 1 | 0.0202142 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0201602 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0201317 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0200952 |
| RPS14 | ribosomal protein S14 | 0.020085 |
| PRDM16 | PR domain containing 16 | 0.0200193 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0199168 |
| SIK3 | SIK family kinase 3 | 0.0198724 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF292 | zinc finger protein 292 | -0.0891911 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0871745 |
| CD44 | CD44 molecule (Indian blood group) | -0.0867972 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0841689 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0822982 |
| TXNRD1 | thioredoxin reductase 1 | -0.0810382 |
| ANLN | anillin, actin binding protein | -0.0782008 |
| CENPF | centromere protein F, 350/400kDa | -0.0737762 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0709608 |
| PTMA | prothymosin, alpha | -0.0656712 |
| DST | dystonin | -0.0637789 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0631275 |
| SBF2 | SET binding factor 2 | -0.0621094 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0605257 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0589652 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0580258 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0578895 |
| SPAG9 | sperm associated antigen 9 | -0.0571171 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0541644 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0535964 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0505181 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0498644 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0492339 |
| MKI67 | marker of proliferation Ki-67 | -0.0489265 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0485891 |
| ASPH | aspartate beta-hydroxylase | -0.0480952 |
| THOC2 | THO complex 2 | -0.0479582 |
| JMJD1C | jumonji domain containing 1C | -0.0479448 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0461822 |
| RPS2 | ribosomal protein S2 | -0.046049 |
| ZFP36 | ZFP36 ring finger protein | -0.0452654 |
| RTN4 | reticulon 4 | -0.0449974 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.044919 |
| TPX2 | TPX2, microtubule-associated | -0.0448311 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.0425724 |
| SNX14 | sorting nexin 14 | -0.0425581 |
| OGA | O-GlcNAcase | -0.0418038 |
| GOLGA4 | golgin A4 | -0.0413944 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0413904 |
| CDK19 | cyclin-dependent kinase 19 | -0.0412215 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.040799 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0394491 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | -0.0388898 |
| SEPTIN7 | septin 7 | -0.0385537 |
| SMYD3 | SET and MYND domain containing 3 | -0.0384629 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0373484 |
| GLCCI1 | glucocorticoid induced 1 | -0.03638 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0359839 |
| RBM39 | RNA binding motif protein 39 | -0.0359137 |
| NKTR | natural killer cell triggering receptor | -0.0359046 |
| XPO1 | exportin 1 | -0.0350401 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0350355 |
| TMEM41B | transmembrane protein 41B | -0.0346209 |
| DSTN | destrin (actin depolymerizing factor) | -0.0344103 |
| ATP13A3 | ATPase type 13A3 | -0.0342248 |
| IPO7 | importin 7 | -0.0341471 |
| BMERB1 | bMERB domain containing 1 | -0.0339818 |
| MATR3 | matrin 3 | -0.033735 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0335945 |
| MED13L | mediator complex subunit 13-like | -0.0331511 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0330066 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0325998 |
| SHTN1 | shootin 1 | -0.0320388 |
| PDE10A | phosphodiesterase 10A | -0.031443 |
| ARRDC3 | arrestin domain containing 3 | -0.0313372 |
| TPR | translocated promoter region, nuclear basket protein | -0.0312837 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0309583 |
| AFAP1 | actin filament associated protein 1 | -0.0306544 |
| EFNA5 | ephrin-A5 | -0.0304921 |
| ZNF780B | zinc finger protein 780B | -0.0300861 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.030073 |
| SMAD3 | SMAD family member 3 | -0.0300028 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0299445 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0298448 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0292566 |
| NFIA | nuclear factor I/A | -0.0291788 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0286701 |
| USP34 | ubiquitin specific peptidase 34 | -0.0284795 |
| ECT2 | epithelial cell transforming 2 | -0.0284792 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0280403 |
| NOP58 | NOP58 ribonucleoprotein | -0.0280207 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0279995 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0279842 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0279658 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0279416 |
| R3HDM1 | R3H domain containing 1 | -0.0278987 |
| PERP | PERP, TP53 apoptosis effector | -0.0277266 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0277109 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0273188 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0273056 |
| HLTF | helicase-like transcription factor | -0.0271651 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.027066 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0270411 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0269525 |
| CCNL1 | cyclin L1 | -0.0268533 |
| CCDC88A | coiled-coil domain containing 88A | -0.0267022 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0266588 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0266179 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0266157 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0263878 |
