| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0457572 |
| ARRDC3 | arrestin domain containing 3 | 0.029852 |
| FAM13A | family with sequence similarity 13, member A | 0.028463 |
| LOC112694756 | uncharaterized LOC112694756 | 0.02777 |
| PLEC | plectin | 0.0245504 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0234326 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0229192 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0222592 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0214022 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0211701 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0207808 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0200314 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.018493 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0170355 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0170146 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0163783 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0159778 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0154219 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0152605 |
| YTHDC1 | YTH domain containing 1 | 0.0152075 |
| PRELID2 | PRELI domain containing 2 | 0.0148171 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0143163 |
| FMNL2 | formin-like 2 | 0.0134664 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0134317 |
| ZNF395 | zinc finger protein 395 | 0.0129693 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0128329 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0124729 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0119708 |
| PGM3 | phosphoglucomutase 3 | 0.0118756 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.011599 |
| GOLGB1 | golgin B1 | 0.011565 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0115561 |
| PTGES2 | prostaglandin E synthase 2 | 0.0115001 |
| HYOU1 | hypoxia up-regulated 1 | 0.0113625 |
| KYNU | kynureninase | 0.0111548 |
| FOXO3 | forkhead box O3 | 0.0111066 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0110613 |
| INTS6 | integrator complex subunit 6 | 0.0110225 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0108579 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0107609 |
| PREPL | prolyl endopeptidase-like | 0.0107458 |
| MATR3 | matrin 3 | 0.0105725 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0105654 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0105317 |
| TFG | TRK-fused gene | 0.0104546 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0104467 |
| FLNA | filamin A, alpha | 0.0104196 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0103514 |
| OGA | O-GlcNAcase | 0.0102403 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0102233 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0101907 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.010008 |
| CADM1 | cell adhesion molecule 1 | 0.0100022 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.00992161 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00990945 |
| SPAG9 | sperm associated antigen 9 | 0.00980383 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00978265 |
| RPS12 | ribosomal protein S12 | 0.00973036 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00965856 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.00965392 |
| ZNF292 | zinc finger protein 292 | 0.00964316 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00954888 |
| RACK1 | receptor for activated C kinase 1 | 0.00941826 |
| XPO1 | exportin 1 | 0.00933309 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00931314 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.00923018 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00922025 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00918222 |
| HBP1 | HMG-box transcription factor 1 | 0.00912317 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00906278 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0090576 |
| USP37 | ubiquitin specific peptidase 37 | 0.00905338 |
| MLEC | malectin | 0.00905073 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.00904636 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00903275 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00898053 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00885977 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.00883199 |
| COG5 | component of oligomeric golgi complex 5 | 0.00881359 |
| FAM219A | family with sequence similarity 219, member A | 0.00876029 |
| NPTN | neuroplastin | 0.00874551 |
| RINT1 | RAD50 interactor 1 | 0.00874327 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.00874131 |
| RYBP | RING1 and YY1 binding protein | 0.00870835 |
| METTL15 | methyltransferase like 15 | 0.00870614 |
| RPL3 | ribosomal protein L3 | 0.00869841 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0086951 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00866701 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0086662 |
| COG6 | component of oligomeric golgi complex 6 | 0.00863753 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00861269 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00860315 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00857685 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00849233 |
| PMM2 | phosphomannomutase 2 | 0.00847283 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.00845195 |
| CD109 | CD109 molecule | 0.00843065 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00842557 |
| TMF1 | TATA element modulatory factor 1 | 0.00839429 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00834007 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.114108 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106751 |
| COL1A1 | collagen, type I, alpha 1 | -0.104756 |
| VIM | vimentin | -0.0983131 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0908263 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0862456 |
| HLA-B | major histocompatibility complex, class I, B | -0.0861715 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0860818 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0842467 |
| COL1A2 | collagen, type I, alpha 2 | -0.0832964 |
| FN1 | fibronectin 1 | -0.080783 |
| POTEF | POTE ankyrin domain family, member F | -0.064776 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0637161 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0586617 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0557182 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.05495 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0536624 |
| MT1X | metallothionein 1X | -0.0493767 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0489045 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0464723 |
| LOX | lysyl oxidase | -0.0460824 |
| CDH13 | cadherin 13 | -0.0455956 |
| CALU | calumenin | -0.0444288 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0408437 |
| MAP1B | microtubule-associated protein 1B | -0.0349428 |
| ENO1 | enolase 1, (alpha) | -0.0348966 |
| TPM4 | tropomyosin 4 | -0.0341534 |
| PTMA | prothymosin, alpha | -0.0329163 |
| HLA-C | major histocompatibility complex, class I, C | -0.0313692 |
| IL6 | interleukin 6 | -0.0307142 |
| GLIS3 | GLIS family zinc finger 3 | -0.0304943 |
| CD44 | CD44 molecule (Indian blood group) | -0.0295454 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0292028 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0288047 |
| PGK1 | phosphoglycerate kinase 1 | -0.02854 |
| ACTG1 | actin gamma 1 | -0.0284016 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0279189 |
| PRSS23 | protease, serine, 23 | -0.0275969 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0274862 |
| CALD1 | caldesmon 1 | -0.0267903 |
| HMGA2 | high mobility group AT-hook 2 | -0.0261037 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0258862 |
| VCL | vinculin | -0.0258559 |
| COL5A1 | collagen, type V, alpha 1 | -0.0246748 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0245559 |
| S100A10 | S100 calcium binding protein A10 | -0.0245107 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0244818 |
| RAI14 | retinoic acid induced 14 | -0.0244641 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0239834 |
| TNS3 | tensin 3 | -0.0237833 |
| COL5A2 | collagen, type V, alpha 2 | -0.0236407 |
| RASAL2 | RAS protein activator like 2 | -0.0235539 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0234083 |
| TPM1 | tropomyosin 1 (alpha) | -0.0228493 |
| S100A6 | S100 calcium binding protein A6 | -0.0226662 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0225541 |
| MAP4 | microtubule-associated protein 4 | -0.0225393 |
| COL3A1 | collagen, type III, alpha 1 | -0.0225259 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.022495 |
| B2M | beta-2-microglobulin | -0.0223557 |
| NAV1 | neuron navigator 1 | -0.0219924 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0215633 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0213532 |
| FRMD4A | FERM domain containing 4A | -0.0210079 |
| SEPTIN7 | septin 7 | -0.0209581 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.02065 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0206319 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0204222 |
| MT2A | metallothionein 2A | -0.0196799 |
| CAVIN1 | caveolae associated protein 1 | -0.018796 |
| TUBA1B | tubulin, alpha 1b | -0.0187851 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0184024 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0183676 |
| ANLN | anillin, actin binding protein | -0.017824 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0177185 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0176835 |
| INHBA | inhibin, beta A | -0.0175251 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0174924 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0173306 |
| AHNAK | AHNAK nucleoprotein | -0.0172389 |
| LAMB1 | laminin, beta 1 | -0.0171303 |
| VEGFC | vascular endothelial growth factor C | -0.0168323 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.016724 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0166273 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0166258 |
| CDK6 | cyclin-dependent kinase 6 | -0.0166015 |
| THY1 | Thy-1 cell surface antigen | -0.016576 |
| JMJD1C | jumonji domain containing 1C | -0.016105 |
| TNNC1 | troponin C type 1 (slow) | -0.0158548 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0158438 |
| H3-3B | H3.3 histone B | -0.0157688 |
| STC1 | stanniocalcin 1 | -0.0156652 |
| TUBB | tubulin, beta class I | -0.0151882 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0149797 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0149459 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0147288 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0145968 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0145341 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0143321 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0142687 |
