| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the NVP-BHG712_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.111968 |
| LOC112694756 | uncharaterized LOC112694756 | 0.109136 |
| CD44 | CD44 molecule (Indian blood group) | 0.1007 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0920143 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0614609 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0586677 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0561742 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0540892 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0498535 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0495708 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0487991 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0478898 |
| IGF2 | insulin-like growth factor 2 | 0.0469536 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0457005 |
| SVIL | supervillin | 0.045684 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0454223 |
| MCL1 | myeloid cell leukemia 1 | 0.042375 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.041466 |
| POTEF | POTE ankyrin domain family, member F | 0.0412575 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0387427 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0380068 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0363223 |
| B2M | beta-2-microglobulin | 0.0356074 |
| PLEC | plectin | 0.0350327 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0347997 |
| LDHA | lactate dehydrogenase A | 0.0340594 |
| NDRG1 | N-myc downstream regulated 1 | 0.0334186 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0325346 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0325128 |
| RPS12 | ribosomal protein S12 | 0.0318977 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0313869 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0313748 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0313361 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0311703 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0310971 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0308769 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0303234 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.030294 |
| ANXA2 | annexin A2 | 0.0300084 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0292102 |
| ANGPTL4 | angiopoietin-like 4 | 0.0290055 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0284022 |
| MED13 | mediator complex subunit 13 | 0.0282104 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0279173 |
| GPC5 | glypican 5 | 0.0273685 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0270057 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0263845 |
| EGR1 | early growth response 1 | 0.026218 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0252334 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0252267 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0251303 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0249009 |
| ACTN1 | actinin, alpha 1 | 0.0246694 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0244857 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0241757 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0238675 |
| TGM2 | transglutaminase 2 | 0.0236771 |
| SMAD3 | SMAD family member 3 | 0.0236765 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0235478 |
| HLA-B | major histocompatibility complex, class I, B | 0.0232344 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0227474 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0225379 |
| ATXN1 | ataxin 1 | 0.0225105 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0224704 |
| MSN | moesin | 0.0223941 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0223207 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0222558 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0220882 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0218333 |
| PCNX4 | pecanex 4 | 0.0217253 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0216191 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0215711 |
| HPCAL1 | hippocalcin-like 1 | 0.0215191 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0214655 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0214358 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.021267 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0209265 |
| ACTG1 | actin gamma 1 | 0.0209217 |
| DNER | delta/notch-like EGF repeat containing | 0.0205769 |
| MYO9B | myosin IXB | 0.0205694 |
| SLC35F2 | solute carrier family 35, member F2 | 0.0202246 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0201135 |
| AHNAK | AHNAK nucleoprotein | 0.0200441 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0199116 |
| LAMA5 | laminin, alpha 5 | 0.0198535 |
| PANX1 | pannexin 1 | 0.0197248 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0196546 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0196477 |
| PODXL | podocalyxin-like | 0.0196004 |
| FLNA | filamin A, alpha | 0.0195736 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0194506 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.0193766 |
| RPL3 | ribosomal protein L3 | 0.0193634 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0191448 |
| PDZD8 | PDZ domain containing 8 | 0.0191283 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0191121 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0189242 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0188987 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0187173 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0187001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.185179 |
| VIM | vimentin | -0.0824816 |
| RBM39 | RNA binding motif protein 39 | -0.0717711 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0600702 |
| DST | dystonin | -0.0591022 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0514446 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0513876 |
| FUS | FUS RNA binding protein | -0.0483326 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0478246 |
| PARD3 | par-3 family cell polarity regulator | -0.0452095 |
| HMGA2 | high mobility group AT-hook 2 | -0.0442344 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0442126 |
| RSF1 | remodeling and spacing factor 1 | -0.0418253 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0415855 |
| DIAPH3 | diaphanous-related formin 3 | -0.0408835 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0407917 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0404618 |
| EXOC4 | exocyst complex component 4 | -0.0400961 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.039785 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0393275 |
| SEPTIN7 | septin 7 | -0.0383719 |
| TPX2 | TPX2, microtubule-associated | -0.0376568 |
| RAD51B | RAD51 paralog B | -0.0375447 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0371939 |
| HMGB1 | high mobility group box 1 | -0.0363396 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0360752 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0356218 |
| SMYD3 | SET and MYND domain containing 3 | -0.0355757 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0355098 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0349206 |
| NAV2 | neuron navigator 2 | -0.0345759 |
| OGA | O-GlcNAcase | -0.0343456 |
| ZNF638 | zinc finger protein 638 | -0.0341922 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0341921 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0341632 |
| AK1 | adenylate kinase 1 | -0.034018 |
| SPAG9 | sperm associated antigen 9 | -0.0338711 |
| PGK1 | phosphoglycerate kinase 1 | -0.0335253 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0328855 |
| PRSS23 | protease, serine, 23 | -0.0328047 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0326822 |
| ERBIN | erbb2 interacting protein | -0.0319181 |
| ZNF292 | zinc finger protein 292 | -0.0313121 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0312456 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0312067 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0310345 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0308933 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0307098 |
| TMEM263 | transmembrane protein 263 | -0.0304363 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.029632 |
| RBM25 | RNA binding motif protein 25 | -0.0295368 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0293432 |
| MYO9A | myosin IXA | -0.0291755 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0289758 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0289679 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0288312 |
| PTMA | prothymosin, alpha | -0.0288155 |
| FBXO11 | F-box protein 11 | -0.0287476 |
| TCF12 | transcription factor 12 | -0.0286324 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0285395 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0283594 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0281088 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0280317 |
| ACER3 | alkaline ceramidase 3 | -0.0280175 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0278364 |
| SNX14 | sorting nexin 14 | -0.0276465 |
| GPC6 | glypican 6 | -0.0275314 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0273862 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0269923 |
| RGS17 | regulator of G-protein signaling 17 | -0.0269534 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0268314 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0266334 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0265256 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0262041 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0259084 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0256709 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0255163 |
| SMAD2 | SMAD family member 2 | -0.0254537 |
| TUBA1B | tubulin, alpha 1b | -0.0254372 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0253022 |
| GNAS | GNAS complex locus | -0.0251942 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0249764 |
| PHIP | pleckstrin homology domain interacting protein | -0.0248567 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.024739 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0245479 |
| DTNA | dystrobrevin, alpha | -0.0243755 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0243508 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0243114 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0241354 |
| PCNX1 | pecanex 1 | -0.0241321 |
| UTRN | utrophin | -0.0241029 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0238145 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0237617 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0235439 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0234878 |
| NF1 | neurofibromin 1 | -0.0232501 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0232059 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0231474 |
| NINL | ninein-like | -0.0230462 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.02291 |
