| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.057955 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0437733 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0388971 |
| INTS6 | integrator complex subunit 6 | 0.0385703 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0361301 |
| MT2A | metallothionein 2A | 0.035316 |
| FAT1 | FAT atypical cadherin 1 | 0.0321331 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.030782 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0296305 |
| FLNB | filamin B, beta | 0.0274873 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0270049 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0244309 |
| RACK1 | receptor for activated C kinase 1 | 0.0243519 |
| FLNA | filamin A, alpha | 0.0242464 |
| RUNX1 | runt-related transcription factor 1 | 0.0239961 |
| RPL37A | ribosomal protein L37a | 0.0238564 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0227326 |
| RPS12 | ribosomal protein S12 | 0.022155 |
| TUFT1 | tuftelin 1 | 0.0216744 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0209083 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0203179 |
| RPS3 | ribosomal protein S3 | 0.0200915 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0199619 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0198145 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0193728 |
| RNF145 | ring finger protein 145 | 0.019012 |
| PLEC | plectin | 0.0188971 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0181932 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0179672 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.017789 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0177471 |
| RPS19 | ribosomal protein S19 | 0.0176774 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0172181 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0169022 |
| CTBP2 | C-terminal binding protein 2 | 0.0168936 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0165962 |
| NPTN | neuroplastin | 0.0162696 |
| RPS17 | ribosomal protein S17 | 0.0162449 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0160731 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0159592 |
| MCL1 | myeloid cell leukemia 1 | 0.0154752 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0153279 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0152746 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0152524 |
| RPL9 | ribosomal protein L9 | 0.0151376 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0150574 |
| POU2F2 | POU class 2 homeobox 2 | 0.014948 |
| CADM1 | cell adhesion molecule 1 | 0.014926 |
| RPL12 | ribosomal protein L12 | 0.0148419 |
| FGF18 | fibroblast growth factor 18 | 0.0147698 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0147452 |
| FERMT2 | fermitin family member 2 | 0.0147367 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0146084 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0145671 |
| FAM13A | family with sequence similarity 13, member A | 0.0144268 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0141451 |
| RPL23 | ribosomal protein L23 | 0.0140153 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0139292 |
| ABLIM1 | actin binding LIM protein 1 | 0.0138652 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0138438 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0136138 |
| FMNL2 | formin-like 2 | 0.0134897 |
| PCBP2 | poly(rC) binding protein 2 | 0.0134113 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0133736 |
| RCOR1 | REST corepressor 1 | 0.0133209 |
| TPM3 | tropomyosin 3 | 0.0131104 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0130574 |
| LMNA | lamin A/C | 0.0129606 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0129512 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0128978 |
| GPATCH2L | G patch domain containing 2-like | 0.0128709 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0128292 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0127835 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0127398 |
| ANGPTL4 | angiopoietin-like 4 | 0.0127093 |
| PGM3 | phosphoglucomutase 3 | 0.0125429 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0124289 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0124288 |
| ARRDC3 | arrestin domain containing 3 | 0.0123317 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0119461 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0118158 |
| MYO1B | myosin IB | 0.0118002 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0117285 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0117043 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.011598 |
| HLA-C | major histocompatibility complex, class I, C | 0.0114965 |
| HELZ | helicase with zinc finger | 0.0114022 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0113744 |
| IGF2 | insulin-like growth factor 2 | 0.0113659 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0113544 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0113444 |
| ATXN1 | ataxin 1 | 0.0112722 |
| LRRC23 | leucine rich repeat containing 23 | 0.011239 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0112356 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0111874 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0109967 |
| VEGFA | vascular endothelial growth factor A | 0.0109192 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0108704 |
| ANXA2 | annexin A2 | 0.0107513 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0105476 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.291231 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.274841 |
| FN1 | fibronectin 1 | -0.189478 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156163 |
| NRG1 | neuregulin 1 | -0.131073 |
| ITGA1 | integrin, alpha 1 | -0.115291 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.098258 |
| SQSTM1 | sequestosome 1 | -0.0956111 |
| HMGA2 | high mobility group AT-hook 2 | -0.0862902 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0855938 |
| TMEM156 | transmembrane protein 156 | -0.0766325 |
| HLA-B | major histocompatibility complex, class I, B | -0.0685884 |
| TMSB4X | thymosin beta 4, X-linked | -0.052069 |
| KLHL5 | kelch-like family member 5 | -0.0503437 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0471151 |
| OSMR | oncostatin M receptor | -0.0462076 |
| PTMA | prothymosin, alpha | -0.0460536 |
| S100A6 | S100 calcium binding protein A6 | -0.0442934 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0425843 |
| CANX | calnexin | -0.0424875 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0423957 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0416533 |
| RAI14 | retinoic acid induced 14 | -0.0409572 |
| SYT1 | synaptotagmin I | -0.0395477 |
| GLIS3 | GLIS family zinc finger 3 | -0.0382842 |
| ETV1 | ets variant 1 | -0.0381652 |
| AOPEP | aminopeptidase O (putative) | -0.0334109 |
| NRP1 | neuropilin 1 | -0.0333703 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0323956 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0315762 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0311381 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0302899 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0296201 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0296005 |
| ETV6 | ets variant 6 | -0.0279429 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0279096 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0275816 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.02728 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0269725 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0263565 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0260141 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0255588 |
| IER3 | immediate early response 3 | -0.0251688 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0250482 |
| SMOX | spermine oxidase | -0.0250318 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.024705 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0242297 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0237536 |
| CENPF | centromere protein F, 350/400kDa | -0.0232942 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0229805 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0225957 |
| CALU | calumenin | -0.0224736 |
| MKI67 | marker of proliferation Ki-67 | -0.0218085 |
| TPR | translocated promoter region, nuclear basket protein | -0.0217315 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0213032 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0211381 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0210423 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0210064 |
| DENND5B | DENN/MADD domain containing 5B | -0.0209592 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0209176 |
| H1-0 | H1.0 linker histone | -0.0206107 |
| FAM20C | family with sequence similarity 20, member C | -0.0205458 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0203007 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0201984 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0200437 |
| TMEM165 | transmembrane protein 165 | -0.019796 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.019789 |
| PLIN2 | perilipin 2 | -0.0197848 |
| RRBP1 | ribosome binding protein 1 | -0.0197823 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.019489 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0194848 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0192468 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0192225 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0190507 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0188828 |
| USP34 | ubiquitin specific peptidase 34 | -0.0188204 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0185361 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0180315 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.018031 |
| SSH1 | slingshot protein phosphatase 1 | -0.0180283 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0175876 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.017442 |
| FDPS | farnesyl diphosphate synthase | -0.0173875 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0173597 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0172845 |
| FAF2 | Fas associated factor family member 2 | -0.0170694 |
| MX2 | MX dynamin-like GTPase 2 | -0.0170674 |
| ASPH | aspartate beta-hydroxylase | -0.0170408 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0170268 |
| BPTF | bromodomain PHD finger transcription factor | -0.0169914 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0168942 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.016645 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0165739 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.016554 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0163277 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0163003 |
| S100A10 | S100 calcium binding protein A10 | -0.0162407 |
| RUNX2 | runt-related transcription factor 2 | -0.0162167 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0160799 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0159272 |
