| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NVP-BHG712 perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NVP-BHG712_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.285518 |
| VIM | vimentin | 0.209718 |
| NDRG1 | N-myc downstream regulated 1 | 0.128296 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0956914 |
| TMSB10 | thymosin beta 10 | 0.0875915 |
| B2M | beta-2-microglobulin | 0.0873963 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0808112 |
| MT2A | metallothionein 2A | 0.0686467 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0672959 |
| FTL | ferritin, light polypeptide | 0.0667053 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0613114 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0589847 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.058933 |
| STC1 | stanniocalcin 1 | 0.0587786 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0576245 |
| ADM | adrenomedullin | 0.0558345 |
| LDHA | lactate dehydrogenase A | 0.0533273 |
| GOLGA4 | golgin A4 | 0.0505801 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0495254 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.049496 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0481778 |
| ENO1 | enolase 1, (alpha) | 0.0461101 |
| CALR | calreticulin | 0.0457372 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0444171 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0440947 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0437382 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0434525 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0432472 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0432224 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0423332 |
| RPS6 | ribosomal protein S6 | 0.0418078 |
| FAM13A | family with sequence similarity 13, member A | 0.041669 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0395249 |
| VEGFA | vascular endothelial growth factor A | 0.0393015 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0391692 |
| HLA-B | major histocompatibility complex, class I, B | 0.0377434 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0367335 |
| INHBA | inhibin, beta A | 0.0356864 |
| RPS19 | ribosomal protein S19 | 0.0343817 |
| RPL37A | ribosomal protein L37a | 0.0337391 |
| ACTG1 | actin gamma 1 | 0.0331961 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0331582 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0330332 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0328153 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0324021 |
| TPI1 | triosephosphate isomerase 1 | 0.0322393 |
| RPS3 | ribosomal protein S3 | 0.0312995 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0311185 |
| RPS12 | ribosomal protein S12 | 0.0306774 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0302939 |
| PKM | pyruvate kinase, muscle | 0.0295556 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.029553 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0291547 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0291114 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0288703 |
| PCBP2 | poly(rC) binding protein 2 | 0.0286427 |
| CALU | calumenin | 0.0283411 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0280244 |
| RPLP1 | ribosomal protein, large, P1 | 0.0272945 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0272262 |
| YBX1 | Y box binding protein 1 | 0.0267096 |
| MSN | moesin | 0.0259778 |
| PTMA | prothymosin, alpha | 0.0258963 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0258872 |
| FMNL2 | formin-like 2 | 0.025863 |
| HLA-A | major histocompatibility complex, class I, A | 0.0256726 |
| FLNA | filamin A, alpha | 0.0254947 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0251335 |
| RACK1 | receptor for activated C kinase 1 | 0.0245314 |
| LMNA | lamin A/C | 0.0241704 |
| RPS8 | ribosomal protein S8 | 0.0239935 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0239588 |
| RUNX1 | runt-related transcription factor 1 | 0.0236814 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0234814 |
| ZNF292 | zinc finger protein 292 | 0.0233873 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0232074 |
| RPL23 | ribosomal protein L23 | 0.0229127 |
| RPL18 | ribosomal protein L18 | 0.0227869 |
| RPL3 | ribosomal protein L3 | 0.0227696 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.022426 |
| RPL19 | ribosomal protein L19 | 0.0218584 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0214426 |
| ARRDC3 | arrestin domain containing 3 | 0.0214334 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0213765 |
| CD44 | CD44 molecule (Indian blood group) | 0.021148 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.021015 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0209502 |
| RPL9 | ribosomal protein L9 | 0.0208025 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0206362 |
| RPL5 | ribosomal protein L5 | 0.0206246 |
| HELZ | helicase with zinc finger | 0.0203574 |
| RPL7 | ribosomal protein L7 | 0.0202166 |
| OGA | O-GlcNAcase | 0.020048 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0199932 |
| NUP58 | nucleoporin 58 | 0.0196967 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0196238 |
| FBN1 | fibrillin 1 | 0.0195468 |
| TMF1 | TATA element modulatory factor 1 | 0.0194241 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0194092 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0194072 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.119099 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0923087 |
| HMGA2 | high mobility group AT-hook 2 | -0.0857091 |
| MMP1 | matrix metallopeptidase 1 | -0.0709578 |
| OXR1 | oxidation resistance 1 | -0.0674976 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0672025 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0647209 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0645779 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.059837 |
| RAI14 | retinoic acid induced 14 | -0.0522604 |
| ASPH | aspartate beta-hydroxylase | -0.0447104 |
| GLIS3 | GLIS family zinc finger 3 | -0.0437028 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0420779 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0384637 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0381312 |
| COL1A1 | collagen, type I, alpha 1 | -0.0380379 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0369809 |
| DIAPH2 | diaphanous-related formin 2 | -0.0364519 |
| AHNAK | AHNAK nucleoprotein | -0.0339785 |
| EMP1 | epithelial membrane protein 1 | -0.0339427 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0322927 |
| FRMD4A | FERM domain containing 4A | -0.0322373 |
| VCL | vinculin | -0.0320587 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0308928 |
| CDH13 | cadherin 13 | -0.028587 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.025676 |
| EGFR | epidermal growth factor receptor | -0.0247001 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0244569 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0244072 |
| CLMP | CXADR-like membrane protein | -0.0235781 |
| NAV1 | neuron navigator 1 | -0.0233495 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0224171 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0218741 |
| NCKAP5 | NCK-associated protein 5 | -0.021439 |
| PRRX1 | paired related homeobox 1 | -0.0212578 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0209555 |
| KIAA1549L | KIAA1549-like | -0.0207618 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0206153 |
| CCDC102B | coiled-coil domain containing 102B | -0.0200366 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0197689 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0185869 |
| SEPTIN11 | septin 11 | -0.0177348 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0174374 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0170366 |
| TSHZ3 | teashirt zinc finger homeobox 3 | -0.0168442 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0164578 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0155647 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0155122 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0154906 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.015153 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0149916 |
| RAB31 | RAB31, member RAS oncogene family | -0.0149809 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0148524 |
| IPO9 | importin 9 | -0.0146531 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0145221 |
| PDE8A | phosphodiesterase 8A | -0.0144892 |
| PRR16 | proline rich 16 | -0.014428 |
| OSMR | oncostatin M receptor | -0.0143855 |
| COL5A3 | collagen, type V, alpha 3 | -0.0143836 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | -0.0141323 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0140845 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0140392 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0140177 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0139465 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0139026 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0136884 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0136768 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0135817 |
| RNF152 | ring finger protein 152 | -0.0135664 |
| MTAP | methylthioadenosine phosphorylase | -0.0132252 |
| KLF12 | Kruppel-like factor 12 | -0.0130064 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0129479 |
| EHBP1 | EH domain binding protein 1 | -0.0128571 |
| FUS | FUS RNA binding protein | -0.0127504 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0126859 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0126708 |
| RSU1 | Ras suppressor protein 1 | -0.012633 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0125534 |
| PLPP3 | phospholipid phosphatase 3 | -0.0125439 |
| RASAL2 | RAS protein activator like 2 | -0.0124247 |
| CHSY3 | chondroitin sulfate synthase 3 | -0.0122297 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0120269 |
| PDE7B | phosphodiesterase 7B | -0.0117591 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0117328 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.011638 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0114997 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0114906 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0111346 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0108552 |
| MTERF1 | mitochondrial transcription termination factor 1 | -0.0107892 |
| CDK14 | cyclin-dependent kinase 14 | -0.0107819 |
| NRP1 | neuropilin 1 | -0.0106983 |
| RHOQ | ras homolog family member Q | -0.0105836 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.0105389 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0104623 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0104424 |
| EXOC4 | exocyst complex component 4 | -0.0104416 |
| BNC2 | basonuclin 2 | -0.0104044 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0104023 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0103818 |
