NVP-BSK805 Gene Set
Genes
29 genes differentially expressed following the NVP-BSK805 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
4.72531
|
|
FDPS
|
farnesyl diphosphate synthase
|
4.7096
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
4.66706
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
4.6463
|
|
INSIG1
|
insulin induced gene 1
|
4.6351
|
|
SQLE
|
squalene epoxidase
|
3.91584
|
|
RAPSN
|
receptor-associated protein of the synapse
|
3.88768
|
|
CYP51A1
|
cytochrome P450, family 51, subfamily A, polypeptide 1
|
3.74756
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
3.58473
|
|
TRIM2
|
tripartite motif containing 2
|
3.5722
|
|
PNPLA3
|
patatin-like phospholipase domain containing 3
|
3.56613
|
|
FADS1
|
fatty acid desaturase 1
|
3.56272
|
|
IDI1
|
isopentenyl-diphosphate delta isomerase 1
|
3.54001
|
|
ERG28
|
ergosterol biosynthesis 28 homolog
|
3.522
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
3.38946
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
3.38127
|
|
HSD17B7
|
hydroxysteroid (17-beta) dehydrogenase 7
|
3.36465
|
|
ACAT2
|
acetyl-CoA acetyltransferase 2
|
3.29856
|
|
MVD
|
mevalonate (diphospho) decarboxylase
|
3.29748
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.21665
|
|
DHCR24
|
24-dehydrocholesterol reductase
|
3.20507
|
|
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
|
3.19313
|
|
LPIN1
|
lipin 1
|
3.1909
|
|
PANK3
|
pantothenate kinase 3
|
3.08102
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GKN1
|
gastrokine 1
|
-3.39991
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
-3.28597
|
|
DNAJC2
|
DnaJ (Hsp40) homolog, subfamily C, member 2
|
-3.0507
|
|
CDC20
|
cell division cycle 20
|
-3.02824
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
-3.00043
|
