| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.09135 |
| MT2A | metallothionein 2A | 0.0762924 |
| OGA | O-GlcNAcase | 0.0591414 |
| FBN1 | fibrillin 1 | 0.0559875 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0538565 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0536753 |
| B2M | beta-2-microglobulin | 0.0532125 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0519958 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0465825 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0465401 |
| SBF2 | SET binding factor 2 | 0.0435752 |
| OPTN | optineurin | 0.0414717 |
| STC1 | stanniocalcin 1 | 0.0414076 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.041256 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0412431 |
| GOLGA4 | golgin A4 | 0.0385781 |
| GPC6 | glypican 6 | 0.0372576 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0365702 |
| RBM25 | RNA binding motif protein 25 | 0.0330173 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0315518 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0308481 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0301974 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0300474 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0298412 |
| UBC | ubiquitin C | 0.0293957 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0283874 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0282337 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0276193 |
| SQSTM1 | sequestosome 1 | 0.0275818 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.027241 |
| MEF2A | myocyte enhancer factor 2A | 0.0260051 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0259706 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0258652 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0258377 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0253675 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0253544 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.025097 |
| C1D | C1D nuclear receptor corepressor | 0.0250001 |
| RBM39 | RNA binding motif protein 39 | 0.0249087 |
| CLU | clusterin | 0.0247164 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0246167 |
| COL1A2 | collagen, type I, alpha 2 | 0.024568 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.024489 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0244463 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0242324 |
| FLNB | filamin B, beta | 0.0241979 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0238432 |
| RNF145 | ring finger protein 145 | 0.0238191 |
| PTMA | prothymosin, alpha | 0.0237137 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0234182 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0224858 |
| ZNF292 | zinc finger protein 292 | 0.022437 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0223566 |
| ARRDC3 | arrestin domain containing 3 | 0.0221743 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0221032 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0219346 |
| ATP13A3 | ATPase type 13A3 | 0.0214409 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0213595 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0211896 |
| SH3BP2 | SH3-domain binding protein 2 | 0.0211856 |
| ITSN2 | intersectin 2 | 0.0210523 |
| SVIL | supervillin | 0.0210383 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.020471 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0203517 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0203056 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0202511 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0201985 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0200546 |
| MYO9A | myosin IXA | 0.0200266 |
| HLA-A | major histocompatibility complex, class I, A | 0.0200171 |
| ANK2 | ankyrin 2, neuronal | 0.0198261 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0196818 |
| RPS2 | ribosomal protein S2 | 0.0195649 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0194455 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0192669 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0192485 |
| RPS6 | ribosomal protein S6 | 0.019241 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0191194 |
| CD44 | CD44 molecule (Indian blood group) | 0.0186781 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0185034 |
| PCBP2 | poly(rC) binding protein 2 | 0.0183798 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0182905 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0180051 |
| LRRC49 | leucine rich repeat containing 49 | 0.0179833 |
| PCM1 | pericentriolar material 1 | 0.0179597 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.017915 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0178495 |
| HIP1 | huntingtin interacting protein 1 | 0.0178157 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0177705 |
| SETD5 | SET domain containing 5 | 0.0177341 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0176544 |
| TMOD1 | tropomodulin 1 | 0.0176428 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0176309 |
| RPS3 | ribosomal protein S3 | 0.0175933 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.017456 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0174558 |
| NAV2 | neuron navigator 2 | 0.0174355 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0173025 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0168751 |
| HMGB2 | high mobility group box 2 | 0.0168048 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | -0.204515 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.190508 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.183672 |
| PODXL | podocalyxin-like | -0.160334 |
| AHNAK | AHNAK nucleoprotein | -0.138866 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133094 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.128967 |
| VIM | vimentin | -0.118796 |
| COL5A1 | collagen, type V, alpha 1 | -0.112318 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.103971 |
| FN1 | fibronectin 1 | -0.103196 |
| SLC39A11 | solute carrier family 39, member 11 | -0.102046 |
| MAP1B | microtubule-associated protein 1B | -0.0929112 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0917923 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0790471 |
| NAV1 | neuron navigator 1 | -0.0741657 |
| S100A10 | S100 calcium binding protein A10 | -0.0699074 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0694119 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0625115 |
| RIGI | RNA sensor RIG-I | -0.0613654 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0584409 |
| SUCNR1 | succinate receptor 1 | -0.0554241 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0552797 |
| EGFR | epidermal growth factor receptor | -0.0543713 |
| FSTL1 | follistatin-like 1 | -0.0523202 |
| CCND1 | cyclin D1 | -0.0521141 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0513826 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0509356 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0501447 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0499944 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0496904 |
| EFNA5 | ephrin-A5 | -0.0487401 |
| CANX | calnexin | -0.0485661 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0468407 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0460378 |
| THBS2 | thrombospondin 2 | -0.0451635 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0449744 |
| LOX | lysyl oxidase | -0.0437634 |
| CSTB | cystatin B (stefin B) | -0.0435959 |
| POTEF | POTE ankyrin domain family, member F | -0.0434127 |
| PRSS23 | protease, serine, 23 | -0.0432914 |
| TMSB10 | thymosin beta 10 | -0.0422054 |
| ASPH | aspartate beta-hydroxylase | -0.0417913 |
| CAVIN1 | caveolae associated protein 1 | -0.0415649 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0400191 |
| TPM4 | tropomyosin 4 | -0.0397287 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0396794 |
| LRRC17 | leucine rich repeat containing 17 | -0.0394639 |
| CYTH3 | cytohesin 3 | -0.0378968 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0377291 |
| MSI2 | musashi RNA-binding protein 2 | -0.0372483 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0368769 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.036842 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0363883 |
| CUX1 | cut-like homeobox 1 | -0.0362487 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0352657 |
| PLXNA2 | plexin A2 | -0.0350447 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0340919 |
| S100A6 | S100 calcium binding protein A6 | -0.03406 |
| FRMD4A | FERM domain containing 4A | -0.0338872 |
| IL7R | interleukin 7 receptor | -0.0338133 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0329824 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0326225 |
| SLC38A1 | solute carrier family 38, member 1 | -0.031817 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0318132 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0317242 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0316677 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0316136 |
| DCLK2 | doublecortin-like kinase 2 | -0.0310015 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0309204 |
| LDHA | lactate dehydrogenase A | -0.0305687 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0302862 |
| LMNA | lamin A/C | -0.0298142 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0291736 |
| NDRG1 | N-myc downstream regulated 1 | -0.0291551 |
| FMN2 | formin 2 | -0.028374 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0283016 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0279406 |
| TAGLN2 | transgelin 2 | -0.0276675 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0273813 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0268703 |
| TAOK1 | TAO kinase 1 | -0.0265229 |
| RASAL2 | RAS protein activator like 2 | -0.0264251 |
| ANXA2 | annexin A2 | -0.0260911 |
| KRT81 | keratin 81, type II | -0.0255277 |
| KIAA1549L | KIAA1549-like | -0.0251911 |
| INTS6 | integrator complex subunit 6 | -0.0250853 |
| PCDH7 | protocadherin 7 | -0.0249471 |
| TPM1 | tropomyosin 1 (alpha) | -0.0247601 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0246555 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0237001 |
| PLAT | plasminogen activator, tissue | -0.0232486 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.02302 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0227828 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0227403 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0226907 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0226575 |
| DENND1A | DENN/MADD domain containing 1A | -0.0222004 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0220359 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0219678 |
