| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.17689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.147734 |
| NLGN1 | neuroligin 1 | 0.120943 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.107298 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0907714 |
| ANXA1 | annexin A1 | 0.0876956 |
| RPS2 | ribosomal protein S2 | 0.0866098 |
| RPL4 | ribosomal protein L4 | 0.0865147 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0747223 |
| HMGA2 | high mobility group AT-hook 2 | 0.0668171 |
| EGR1 | early growth response 1 | 0.0665735 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0622355 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0620826 |
| ENO1 | enolase 1, (alpha) | 0.059661 |
| EHBP1 | EH domain binding protein 1 | 0.0595764 |
| DST | dystonin | 0.0587491 |
| SET | SET nuclear proto-oncogene | 0.057546 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0556496 |
| EZR | ezrin | 0.054982 |
| RPS3 | ribosomal protein S3 | 0.0548965 |
| TPM3 | tropomyosin 3 | 0.0527667 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0491332 |
| TPI1 | triosephosphate isomerase 1 | 0.0487618 |
| RPS12 | ribosomal protein S12 | 0.046951 |
| ADIPOR2 | adiponectin receptor 2 | 0.0459723 |
| YBX3 | Y box binding protein 3 | 0.0440276 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0437717 |
| CCN2 | cellular communication network factor 2 | 0.0435517 |
| PTMA | prothymosin, alpha | 0.0430819 |
| MKI67 | marker of proliferation Ki-67 | 0.0408521 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0391644 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0383025 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0382058 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0380921 |
| HDGF | hepatoma-derived growth factor | 0.0378383 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0376357 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0373054 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0369555 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0367638 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0353489 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0349708 |
| PDGFC | platelet derived growth factor C | 0.0346668 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0346055 |
| HLA-A | major histocompatibility complex, class I, A | 0.0344073 |
| ASPH | aspartate beta-hydroxylase | 0.0342493 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.033731 |
| NEBL | nebulette | 0.0328779 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0319174 |
| JMJD1C | jumonji domain containing 1C | 0.0310856 |
| CENPF | centromere protein F, 350/400kDa | 0.0310173 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0309945 |
| RBM39 | RNA binding motif protein 39 | 0.0307614 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0303348 |
| RPL18 | ribosomal protein L18 | 0.0292654 |
| RPL26 | ribosomal protein L26 | 0.0292525 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0290825 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0290554 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0286614 |
| RACK1 | receptor for activated C kinase 1 | 0.0285563 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0283388 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0283278 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0282562 |
| KIF5B | kinesin family member 5B | 0.0279816 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0279162 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0275954 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.0275387 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0271776 |
| ZNF146 | zinc finger protein 146 | 0.027096 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0270292 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0268455 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0266554 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0266418 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0264839 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0264586 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0262374 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.0260969 |
| BRD2 | bromodomain containing 2 | 0.0260615 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0260313 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0259035 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0257881 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0257874 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0255919 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0254284 |
| TLN1 | talin 1 | 0.0254024 |
| VIM | vimentin | 0.0252777 |
| ACTG1 | actin gamma 1 | 0.0248028 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0247973 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0247716 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0247576 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0247065 |
| USP53 | ubiquitin specific peptidase 53 | 0.0245502 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0243656 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0239622 |
| NHSL1 | NHS-like 1 | 0.0238234 |
| SETX | senataxin | 0.0236674 |
| HDAC9 | histone deacetylase 9 | 0.0236606 |
| RPS18 | ribosomal protein S18 | 0.0235919 |
| DSPP | dentin sialophosphoprotein | 0.0231119 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0229745 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0222347 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.429567 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0659597 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.054168 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0494286 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0487023 |
| AHNAK | AHNAK nucleoprotein | -0.0484623 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0482519 |
| CXADR | coxsackie virus and adenovirus receptor | -0.048034 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.045351 |
| RPS23 | ribosomal protein S23 | -0.0449167 |
| RPL38 | ribosomal protein L38 | -0.0445032 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0435344 |
| CPOX | coproporphyrinogen oxidase | -0.0416834 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0414196 |
| RPS24 | ribosomal protein S24 | -0.0407022 |
| RPL19 | ribosomal protein L19 | -0.0403432 |
| MGAT4C | MGAT4 family, member C | -0.0398036 |
| ZNF217 | zinc finger protein 217 | -0.0396068 |
| SETD5 | SET domain containing 5 | -0.0395291 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.035849 |
| RPLP0 | ribosomal protein, large, P0 | -0.0355602 |
| RPS15 | ribosomal protein S15 | -0.0354986 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0346605 |
| NEK7 | NIMA-related kinase 7 | -0.0342339 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0336683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321714 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0309591 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0308406 |
| TXNRD1 | thioredoxin reductase 1 | -0.0300033 |
| RPL8 | ribosomal protein L8 | -0.0298938 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0295889 |
| MMP12 | matrix metallopeptidase 12 | -0.0291341 |
| TMSB10 | thymosin beta 10 | -0.0289502 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0289487 |
| GASK1B | golgi associated kinase 1B | -0.0286797 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0280343 |
| UBC | ubiquitin C | -0.0273778 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0271261 |
| HMGA1 | high mobility group AT-hook 1 | -0.0269241 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0268393 |
| ECT2 | epithelial cell transforming 2 | -0.0265738 |
| RPL36A | ribosomal protein L36a | -0.0264499 |
| AREG | amphiregulin | -0.0262968 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0262033 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0258081 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0254362 |
| ZFR | zinc finger RNA binding protein | -0.0254113 |
| CANX | calnexin | -0.0251344 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0251008 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0250772 |
| RPS27A | ribosomal protein S27a | -0.0248139 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0247536 |
| IL6ST | interleukin 6 signal transducer | -0.024285 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0241989 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.024188 |
| RPL7 | ribosomal protein L7 | -0.0240198 |
| RPS21 | ribosomal protein S21 | -0.0238469 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0237735 |
| TNPO1 | transportin 1 | -0.0236928 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0235699 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0235238 |
| RPL34 | ribosomal protein L34 | -0.0234397 |
| RPS29 | ribosomal protein S29 | -0.0233907 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0233845 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0231379 |
| RPLP1 | ribosomal protein, large, P1 | -0.0229663 |
| H3-3B | H3.3 histone B | -0.0228143 |
| RPL32 | ribosomal protein L32 | -0.0226772 |
| KLHL24 | kelch-like family member 24 | -0.0225672 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0224649 |
| CCNI | cyclin I | -0.0217068 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0215949 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0214679 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0213589 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0213332 |
| NF1 | neurofibromin 1 | -0.0211407 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0209727 |
| ETNK1 | ethanolamine kinase 1 | -0.0207379 |
| WWOX | WW domain containing oxidoreductase | -0.0206284 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0205937 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0203336 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0202027 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0200679 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0200525 |
| RPS25 | ribosomal protein S25 | -0.0199257 |
| TMEM123 | transmembrane protein 123 | -0.0197245 |
| NEMF | nuclear export mediator factor | -0.0196257 |
| RPL11 | ribosomal protein L11 | -0.0196166 |
| H2AZ1 | H2A.Z variant histone 1 | -0.0195441 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0192618 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0190612 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | -0.0188649 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0187649 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0187477 |
| RHOA | ras homolog family member A | -0.0187198 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0186159 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0185256 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0184661 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0184201 |
| RPS16 | ribosomal protein S16 | -0.0182748 |
