| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.164549 |
| RPL4 | ribosomal protein L4 | 0.106761 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0530979 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0353691 |
| TMSB4X | thymosin beta 4, X-linked | 0.0351315 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0348785 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0331709 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0330641 |
| RPL23 | ribosomal protein L23 | 0.0321059 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0319958 |
| RPS12 | ribosomal protein S12 | 0.0305114 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0292365 |
| RPS17 | ribosomal protein S17 | 0.0276102 |
| EGFR | epidermal growth factor receptor | 0.0269738 |
| RPS14 | ribosomal protein S14 | 0.02627 |
| KAZN | kazrin, periplakin interacting protein | 0.0258518 |
| KLHDC10 | kelch domain containing 10 | 0.0254607 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0252313 |
| RBM39 | RNA binding motif protein 39 | 0.0251392 |
| RPS18 | ribosomal protein S18 | 0.0249369 |
| ATRNL1 | attractin-like 1 | 0.0248792 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0248313 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0245997 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.024092 |
| ENO1 | enolase 1, (alpha) | 0.0239734 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0236163 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0231204 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0229235 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0228642 |
| RBM25 | RNA binding motif protein 25 | 0.0225857 |
| FHIT | fragile histidine triad | 0.0221275 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0218339 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.0218263 |
| GANAB | glucosidase, alpha; neutral AB | 0.0215185 |
| RASA2 | RAS p21 protein activator 2 | 0.0214327 |
| RPLP1 | ribosomal protein, large, P1 | 0.0213024 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0212324 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0210196 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0209903 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.020966 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0207079 |
| WWOX | WW domain containing oxidoreductase | 0.0206489 |
| YY1 | YY1 transcription factor | 0.0204944 |
| CNN3 | calponin 3, acidic | 0.0204196 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.0202834 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0201204 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0199771 |
| ATXN10 | ataxin 10 | 0.0199467 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0198591 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0197074 |
| BCOR | BCL6 corepressor | 0.0196223 |
| IL17RD | interleukin 17 receptor D | 0.0195021 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 | 0.0194491 |
| RPL32 | ribosomal protein L32 | 0.0191095 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0189862 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0187857 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.018711 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.018639 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.0184976 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0184557 |
| DCTN4 | dynactin 4 (p62) | 0.0184535 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0182888 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0181953 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0181815 |
| HOXC10 | homeobox C10 | 0.0179234 |
| SMIM44 | small integral membrane protein 44 | 0.0178988 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0178534 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0177767 |
| PCDH7 | protocadherin 7 | 0.0177705 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0177574 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0177295 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0176269 |
| MYO9A | myosin IXA | 0.0175105 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.0174998 |
| PCDHB11 | protocadherin beta 11 | 0.0172768 |
| CALR | calreticulin | 0.0172446 |
| EPHB2 | EPH receptor B2 | 0.0172218 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0172008 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0171653 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0170802 |
| CBX3 | chromobox homolog 3 | 0.0170283 |
| PTPRS | protein tyrosine phosphatase, receptor type, S | 0.0170143 |
| PELP1 | proline, glutamate and leucine rich protein 1 | 0.0168815 |
| NCOA3 | nuclear receptor coactivator 3 | 0.016854 |
| CFAP44 | cilia and flagella associated protein 44 | 0.016777 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0167023 |
| NRBP1 | nuclear receptor binding protein 1 | 0.0166911 |
| BIN3 | bridging integrator 3 | 0.0165894 |
| TRIM56 | tripartite motif containing 56 | 0.0165737 |
| PRTG | protogenin | 0.0165423 |
| NIN | ninein (GSK3B interacting protein) | 0.0164244 |
| MINK1 | misshapen-like kinase 1 | 0.016424 |
| METTL14 | methyltransferase like 14 | 0.0164096 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0162636 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0162458 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.0160629 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | 0.0160575 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0159918 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0159865 |
| PBRM1 | polybromo 1 | 0.0159716 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.173797 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145323 |
| SEPTIN11 | septin 11 | -0.0886018 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0867885 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0861308 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0846426 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0770016 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0762143 |
| NFIB | nuclear factor I/B | -0.0740703 |
| PARD3 | par-3 family cell polarity regulator | -0.0728462 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0719355 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0717423 |
| USP3 | ubiquitin specific peptidase 3 | -0.0708433 |
| HMGA2 | high mobility group AT-hook 2 | -0.070786 |
| PEG10 | paternally expressed 10 | -0.0687632 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0687557 |
| ERBIN | erbb2 interacting protein | -0.0656751 |
| ZNF292 | zinc finger protein 292 | -0.0636428 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0632901 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0595994 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0593231 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0580279 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0577614 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0576213 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0574701 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.056942 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0561501 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0560159 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0560049 |
| IGF2 | insulin-like growth factor 2 | -0.0551647 |
| SPAG9 | sperm associated antigen 9 | -0.0548374 |
| MEIS2 | Meis homeobox 2 | -0.0538752 |
| COL1A2 | collagen, type I, alpha 2 | -0.0532167 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.052767 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0525934 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0523852 |
| JMJD1C | jumonji domain containing 1C | -0.0520471 |
| SBF2 | SET binding factor 2 | -0.0509382 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0494829 |
| PHIP | pleckstrin homology domain interacting protein | -0.0489702 |
| QKI | QKI, KH domain containing, RNA binding | -0.0480583 |
| FBXO11 | F-box protein 11 | -0.0465294 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.046268 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0460493 |
| VEGFA | vascular endothelial growth factor A | -0.046004 |
| CTBP2 | C-terminal binding protein 2 | -0.0458984 |
| KIF13A | kinesin family member 13A | -0.0458706 |
| NBAS | neuroblastoma amplified sequence | -0.0443423 |
| UTRN | utrophin | -0.0441534 |
| TSC22D1 | TSC22 domain family, member 1 | -0.042829 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0427593 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0423368 |
| CERT1 | ceramide transporter 1 | -0.0422675 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0421555 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0410922 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0407157 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.040639 |
| CENPF | centromere protein F, 350/400kDa | -0.0399886 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0398067 |
| HMGA1 | high mobility group AT-hook 1 | -0.0395535 |
| PGK1 | phosphoglycerate kinase 1 | -0.0393432 |
| CDK19 | cyclin-dependent kinase 19 | -0.0392215 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0388159 |
| RLF | rearranged L-myc fusion | -0.038736 |
| PHF3 | PHD finger protein 3 | -0.0386387 |
| IER3 | immediate early response 3 | -0.0385254 |
| RYBP | RING1 and YY1 binding protein | -0.0384967 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0377298 |
| ENAH | enabled homolog (Drosophila) | -0.0376107 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0375463 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.036924 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0368399 |
| USP24 | ubiquitin specific peptidase 24 | -0.0365868 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0365603 |
| KIF11 | kinesin family member 11 | -0.0364737 |
| ZFR | zinc finger RNA binding protein | -0.0362391 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0360491 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0359702 |
| HBP1 | HMG-box transcription factor 1 | -0.03591 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0358562 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0357683 |
| NDRG1 | N-myc downstream regulated 1 | -0.035749 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0353622 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.035343 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0352843 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0351462 |
| TAOK1 | TAO kinase 1 | -0.0351308 |
| SNX9 | sorting nexin 9 | -0.03495 |
| RHEB | Ras homolog enriched in brain | -0.0349203 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0342946 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0341882 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0340408 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0336651 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0335759 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0332062 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0324588 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | -0.0323456 |
| XPO1 | exportin 1 | -0.0323278 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0320914 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0320505 |
