| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RAD51B | RAD51 paralog B | 0.0905343 |
| RPL4 | ribosomal protein L4 | 0.0696105 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0549845 |
| CADM2 | cell adhesion molecule 2 | 0.0530597 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0525326 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0492548 |
| RPS2 | ribosomal protein S2 | 0.0465702 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0435762 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0399761 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0373056 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0366022 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.034599 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0338899 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0332975 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0316938 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.030577 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0291701 |
| DST | dystonin | 0.0286318 |
| EGR1 | early growth response 1 | 0.0286057 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.02835 |
| EFNA5 | ephrin-A5 | 0.028289 |
| CENPF | centromere protein F, 350/400kDa | 0.0281605 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0276462 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0253871 |
| RPS18 | ribosomal protein S18 | 0.025345 |
| ATG10 | autophagy related 10 | 0.0247764 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0245487 |
| PDE10A | phosphodiesterase 10A | 0.0238646 |
| GOLGA4 | golgin A4 | 0.0236788 |
| PNN | pinin, desmosome associated protein | 0.0236034 |
| CDH18 | cadherin 18, type 2 | 0.0235423 |
| ASPH | aspartate beta-hydroxylase | 0.022929 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0227287 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0224442 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0224379 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.021068 |
| SET | SET nuclear proto-oncogene | 0.0209235 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0206358 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0199266 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0192645 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0191972 |
| NEBL | nebulette | 0.0190008 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0187534 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0185714 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0182082 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0181882 |
| TMSB4X | thymosin beta 4, X-linked | 0.0179534 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0176535 |
| TPM3 | tropomyosin 3 | 0.0174982 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0174979 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0172161 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0171214 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.01654 |
| OSMR | oncostatin M receptor | 0.0165372 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0163935 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0163438 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0162693 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.016134 |
| CALD1 | caldesmon 1 | 0.0160216 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0159783 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0159489 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0159 |
| FHIT | fragile histidine triad | 0.0158616 |
| HHIP | hedgehog interacting protein | 0.0157866 |
| ZNF146 | zinc finger protein 146 | 0.015773 |
| RBM39 | RNA binding motif protein 39 | 0.0155795 |
| PHF14 | PHD finger protein 14 | 0.0152314 |
| EXOC4 | exocyst complex component 4 | 0.015042 |
| RBM25 | RNA binding motif protein 25 | 0.0150081 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0148943 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.014724 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0146632 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0146403 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0146039 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0144785 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.014314 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.014278 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0141856 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0141219 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.014065 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0138717 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0138411 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | 0.0136943 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0136223 |
| WDR43 | WD repeat domain 43 | 0.013562 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0135164 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0134847 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0134786 |
| PRELID2 | PRELI domain containing 2 | 0.0133894 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0133456 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0133327 |
| ANKRD26 | ankyrin repeat domain 26 | 0.0133259 |
| PUDP | pseudouridine 5'-phosphatase | 0.0132697 |
| ATP5ME | ATP synthase membrane subunit e | 0.0131099 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.013074 |
| LMO7 | LIM domain 7 | 0.0130501 |
| ANK2 | ankyrin 2, neuronal | 0.0130077 |
| SP100 | SP100 nuclear antigen | 0.0129977 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0129859 |
| HLA-A | major histocompatibility complex, class I, A | 0.0129396 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.362876 |
| ACTG1 | actin gamma 1 | -0.100472 |
| LDHA | lactate dehydrogenase A | -0.0977541 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0891753 |
| UBC | ubiquitin C | -0.0868095 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0735059 |
| RPL11 | ribosomal protein L11 | -0.0723813 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0710398 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0700524 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0593638 |
| WDR45B | WD repeat domain 45B | -0.0563757 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0561793 |
| RPS11 | ribosomal protein S11 | -0.0552909 |
| DEK | DEK proto-oncogene | -0.0548486 |
| RPLP0 | ribosomal protein, large, P0 | -0.0502886 |
| RPS21 | ribosomal protein S21 | -0.049994 |
| FAM162A | family with sequence similarity 162, member A | -0.0492638 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0488756 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0484833 |
| RPL28 | ribosomal protein L28 | -0.0481529 |
| PGK1 | phosphoglycerate kinase 1 | -0.0476183 |
| NFIA | nuclear factor I/A | -0.0474647 |
| GNAS | GNAS complex locus | -0.046879 |
| TAOK1 | TAO kinase 1 | -0.0464736 |
| RPS24 | ribosomal protein S24 | -0.0461633 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0455977 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0445219 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0442641 |
| TMSB10 | thymosin beta 10 | -0.0431452 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0430129 |
| RLF | rearranged L-myc fusion | -0.0424916 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0421603 |
| RPL7A | ribosomal protein L7a | -0.0417187 |
| ENAH | enabled homolog (Drosophila) | -0.0413595 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0411347 |
| TPD52 | tumor protein D52 | -0.0409854 |
| RPL8 | ribosomal protein L8 | -0.0401089 |
| RHOA | ras homolog family member A | -0.0400813 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0392734 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0390839 |
| SETD5 | SET domain containing 5 | -0.0389248 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0388298 |
| PTMA | prothymosin, alpha | -0.0383788 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0381997 |
| JMJD1C | jumonji domain containing 1C | -0.0379394 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0376912 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0371653 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0371399 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0364514 |
| CCNI | cyclin I | -0.0356464 |
| RPS29 | ribosomal protein S29 | -0.0354675 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0352152 |
| RPS15 | ribosomal protein S15 | -0.035165 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0350649 |
| CCDC47 | coiled-coil domain containing 47 | -0.0350213 |
| ARFGEF3 | ARFGEF family member 3 | -0.0344174 |
| RPS8 | ribosomal protein S8 | -0.0342076 |
| PARD3 | par-3 family cell polarity regulator | -0.0340752 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0339766 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0339494 |
| PKM | pyruvate kinase, muscle | -0.0338543 |
| RPS27A | ribosomal protein S27a | -0.0333752 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.033299 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0331219 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.032824 |
| SRPK2 | SRSF protein kinase 2 | -0.0319864 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0319744 |
| RPL19 | ribosomal protein L19 | -0.0319532 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0318369 |
| APP | amyloid beta (A4) precursor protein | -0.0317246 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0316453 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0311534 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0306476 |
| FNBP1L | formin binding protein 1-like | -0.0303012 |
| PEG10 | paternally expressed 10 | -0.0299084 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0296188 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0295139 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0293842 |
| RPL38 | ribosomal protein L38 | -0.029362 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0292497 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0292207 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0290974 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.02897 |
| RPL36A | ribosomal protein L36a | -0.0289028 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0288487 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0287213 |
| GLG1 | golgi glycoprotein 1 | -0.0281765 |
| RPS19 | ribosomal protein S19 | -0.027882 |
| TENM3 | teneurin transmembrane protein 3 | -0.0278042 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0276501 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.027604 |
| S100A9 | S100 calcium binding protein A9 | -0.0274747 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0273589 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0273466 |
| CALU | calumenin | -0.0273172 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0273152 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0273001 |
| ENO1 | enolase 1, (alpha) | -0.0272933 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0272471 |
| AUTS2 | autism susceptibility candidate 2 | -0.0271833 |