| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0524754 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0489986 |
| EGR1 | early growth response 1 | 0.0444568 |
| RBM39 | RNA binding motif protein 39 | 0.0391121 |
| RPL4 | ribosomal protein L4 | 0.0380828 |
| VGF | VGF nerve growth factor inducible | 0.0373456 |
| PRRC2C | proline-rich coiled-coil 2C | 0.034563 |
| RPS2 | ribosomal protein S2 | 0.0333873 |
| BRD2 | bromodomain containing 2 | 0.0300515 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0286534 |
| RBM25 | RNA binding motif protein 25 | 0.0271892 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259784 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0257622 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0243865 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0242426 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0234948 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0234651 |
| JUN | jun proto-oncogene | 0.0233082 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.023097 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0227451 |
| RPS12 | ribosomal protein S12 | 0.0222576 |
| ENO1 | enolase 1, (alpha) | 0.0217085 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0206192 |
| POM121C | POM121 transmembrane nucleoporin C | 0.020511 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0204681 |
| SEM1 | SEM1 26S proteasome subunit | 0.0200122 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0197962 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0186977 |
| TOP1 | topoisomerase (DNA) I | 0.0184774 |
| SET | SET nuclear proto-oncogene | 0.01746 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0174206 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0172747 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0169128 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0166604 |
| DHFR | dihydrofolate reductase | 0.0161585 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0159548 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0158255 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0157716 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0156979 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0155705 |
| TMF1 | TATA element modulatory factor 1 | 0.0155092 |
| EZR | ezrin | 0.0150144 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0147887 |
| VCL | vinculin | 0.0146798 |
| RPS15A | ribosomal protein S15a | 0.0146314 |
| TPM3 | tropomyosin 3 | 0.0145765 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0145662 |
| UBXN4 | UBX domain protein 4 | 0.0144605 |
| LRRC23 | leucine rich repeat containing 23 | 0.0144584 |
| SON | SON DNA binding protein | 0.0140293 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0138619 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0137877 |
| TMEM255B | transmembrane protein 255B | 0.0135167 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0135162 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0134011 |
| RPS18 | ribosomal protein S18 | 0.0134009 |
| ATF4 | activating transcription factor 4 | 0.0133973 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.013366 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0130443 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0128849 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0128696 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0128518 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0128163 |
| ATP11A | ATPase, class VI, type 11A | 0.0128035 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0126711 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0126604 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0126036 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0124249 |
| VMP1 | vacuole membrane protein 1 | 0.0123437 |
| RAD51B | RAD51 paralog B | 0.0122057 |
| RPS3 | ribosomal protein S3 | 0.0120637 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0120573 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0120411 |
| RPL18 | ribosomal protein L18 | 0.0118273 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0117142 |
| HLA-A | major histocompatibility complex, class I, A | 0.0116095 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0116008 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0115945 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0115255 |
| RPL3 | ribosomal protein L3 | 0.0113534 |
| NOP58 | NOP58 ribonucleoprotein | 0.0112687 |
| IER2 | immediate early response 2 | 0.0110698 |
| NRP2 | neuropilin 2 | 0.0110681 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0110169 |
| RPL36 | ribosomal protein L36 | 0.010958 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0109421 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.010784 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0106543 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0106468 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0106463 |
| PER1 | period circadian clock 1 | 0.0104855 |
| RPL26 | ribosomal protein L26 | 0.0104611 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0103981 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.010369 |
| NRDC | nardilysin convertase | 0.0103114 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0102693 |
| DIAPH1 | diaphanous-related formin 1 | 0.0101945 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0100968 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0100234 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.00998579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.496756 |
| FN1 | fibronectin 1 | -0.483529 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.173734 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0903078 |
| GPC6 | glypican 6 | -0.0828963 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0798434 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.076555 |
| VIM | vimentin | -0.0678426 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0671901 |
| NDRG1 | N-myc downstream regulated 1 | -0.0668513 |
| PGK1 | phosphoglycerate kinase 1 | -0.0596582 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0586827 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0581972 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0557881 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0499045 |
| AHNAK | AHNAK nucleoprotein | -0.0488721 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0484626 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0465201 |
| CD109 | CD109 molecule | -0.0439456 |
| RHEB | Ras homolog enriched in brain | -0.0435484 |
| SRPK2 | SRSF protein kinase 2 | -0.0425252 |
| S100A6 | S100 calcium binding protein A6 | -0.0416708 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0415081 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0393203 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0387099 |
| CANX | calnexin | -0.0386839 |
| UBC | ubiquitin C | -0.0378636 |
| ACTG1 | actin gamma 1 | -0.0376968 |
| TMEM123 | transmembrane protein 123 | -0.0372973 |
| IER3 | immediate early response 3 | -0.0368859 |
| SFTPA2 | surfactant protein A2 | -0.0364709 |
| CALU | calumenin | -0.0363671 |
| RYBP | RING1 and YY1 binding protein | -0.0360989 |
| TNNC1 | troponin C type 1 (slow) | -0.0357022 |
| CDC73 | cell division cycle 73 | -0.0354302 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0345458 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0341337 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0340586 |
| COG5 | component of oligomeric golgi complex 5 | -0.0338353 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0333478 |
| PTK2 | protein tyrosine kinase 2 | -0.0323521 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0320928 |
| CTSD | cathepsin D | -0.0315102 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0314296 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0312606 |
| TRIM2 | tripartite motif containing 2 | -0.0305183 |
| A2M | alpha-2-macroglobulin | -0.0304579 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0303864 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0299296 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0298642 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0298125 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0294579 |
| FOXJ3 | forkhead box J3 | -0.0293718 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0291438 |
| FMNL2 | formin-like 2 | -0.0291006 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0289929 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0289672 |
| LDHA | lactate dehydrogenase A | -0.0288392 |
| ANXA2 | annexin A2 | -0.0287017 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0285652 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0283005 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0281609 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0281445 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0277029 |
| NHSL1 | NHS-like 1 | -0.0272023 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0267744 |
| TAGLN2 | transgelin 2 | -0.0262765 |
| RHOA | ras homolog family member A | -0.0262372 |
| S100A10 | S100 calcium binding protein A10 | -0.0261427 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0252257 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0251534 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0243694 |
| VGLL4 | vestigial-like family member 4 | -0.0242452 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0240912 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0238973 |
| RTN4 | reticulon 4 | -0.023849 |
| GLG1 | golgi glycoprotein 1 | -0.0237903 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.0234892 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0233902 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0232142 |
| CUX1 | cut-like homeobox 1 | -0.0230892 |
| SDC2 | syndecan 2 | -0.0222189 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0217048 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0214309 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0214055 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0210388 |
| APP | amyloid beta (A4) precursor protein | -0.0208595 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0207748 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0207152 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0206168 |
| S100A9 | S100 calcium binding protein A9 | -0.0205952 |
| MTPN | myotrophin | -0.0205449 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0204742 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0204097 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0198797 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 | -0.0198708 |
| MEF2A | myocyte enhancer factor 2A | -0.019792 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0195337 |
| TMEM263 | transmembrane protein 263 | -0.0194473 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0194199 |
