| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EIF1 | eukaryotic translation initiation factor 1 | 0.132017 |
| PTMA | prothymosin, alpha | 0.117364 |
| RBM39 | RNA binding motif protein 39 | 0.0988474 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0863754 |
| RPL4 | ribosomal protein L4 | 0.0804373 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0765299 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0733673 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0619553 |
| HLA-A | major histocompatibility complex, class I, A | 0.060077 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0567369 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0551173 |
| OGA | O-GlcNAcase | 0.0516548 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.050136 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0474938 |
| EZR | ezrin | 0.0465096 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0444579 |
| SPAG9 | sperm associated antigen 9 | 0.0443499 |
| RPS2 | ribosomal protein S2 | 0.0416075 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0396521 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0395707 |
| TOP1 | topoisomerase (DNA) I | 0.0381605 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0378907 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0358987 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0332445 |
| RTN4 | reticulon 4 | 0.0325209 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0318383 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0315035 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0308337 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0308121 |
| TFG | TRK-fused gene | 0.0298237 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0296763 |
| NUP58 | nucleoporin 58 | 0.0295845 |
| CDC73 | cell division cycle 73 | 0.0295825 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0287001 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0282666 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0278616 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0271485 |
| NOP58 | NOP58 ribonucleoprotein | 0.0268189 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0264515 |
| DSPP | dentin sialophosphoprotein | 0.0264442 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0259177 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0253966 |
| RRBP1 | ribosome binding protein 1 | 0.0250919 |
| FAM13A | family with sequence similarity 13, member A | 0.0250694 |
| YTHDC1 | YTH domain containing 1 | 0.025067 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0249626 |
| HMGB2 | high mobility group box 2 | 0.0247084 |
| EREG | epiregulin | 0.0246107 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0244858 |
| ABI1 | abl-interactor 1 | 0.0242531 |
| H1-0 | H1.0 linker histone | 0.0242064 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0240713 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0239477 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0238575 |
| ANXA1 | annexin A1 | 0.0234957 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.023374 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.023161 |
| CD2AP | CD2-associated protein | 0.0231041 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0230982 |
| TMSB4X | thymosin beta 4, X-linked | 0.022888 |
| PNN | pinin, desmosome associated protein | 0.0228492 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.022828 |
| MATR3 | matrin 3 | 0.0225497 |
| JUN | jun proto-oncogene | 0.0223148 |
| GOLGA4 | golgin A4 | 0.0221722 |
| TJP1 | tight junction protein 1 | 0.0217698 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0215534 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0213385 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0210773 |
| LAMB3 | laminin, beta 3 | 0.0208971 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0208518 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0204566 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0203367 |
| ZNF292 | zinc finger protein 292 | 0.0201833 |
| USP3 | ubiquitin specific peptidase 3 | 0.0201418 |
| CCNL1 | cyclin L1 | 0.020088 |
| BICC1 | BicC family RNA binding protein 1 | 0.0197157 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0196532 |
| RBM25 | RNA binding motif protein 25 | 0.0196052 |
| RPS18 | ribosomal protein S18 | 0.019499 |
| TPR | translocated promoter region, nuclear basket protein | 0.0189453 |
| SET | SET nuclear proto-oncogene | 0.0188708 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0187434 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0187136 |
| CLINT1 | clathrin interactor 1 | 0.018653 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0186249 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0185684 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0185341 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0183175 |
| YME1L1 | YME1-like 1 ATPase | 0.0183086 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0182712 |
| LMO7 | LIM domain 7 | 0.0182288 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0180976 |
| STC2 | stanniocalcin 2 | 0.0179469 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0178975 |
| LOX | lysyl oxidase | 0.0178969 |
| QKI | QKI, KH domain containing, RNA binding | 0.0178314 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0177879 |
| NEK7 | NIMA-related kinase 7 | 0.0176822 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0176606 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.385748 |
| MT2A | metallothionein 2A | -0.168939 |
| NDRG1 | N-myc downstream regulated 1 | -0.155289 |
| POTEF | POTE ankyrin domain family, member F | -0.139559 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.100279 |
| HMGA1 | high mobility group AT-hook 1 | -0.0841629 |
| PKM | pyruvate kinase, muscle | -0.0820865 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0800697 |
| KRT19 | keratin 19, type I | -0.0774969 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0749072 |
| TMSB10 | thymosin beta 10 | -0.0711314 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0686914 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0686032 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0636466 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0621194 |
| CDCP1 | CUB domain containing protein 1 | -0.0614395 |
| AHNAK | AHNAK nucleoprotein | -0.0557392 |
| LAMC2 | laminin, gamma 2 | -0.0555589 |
| MMP7 | matrix metallopeptidase 7 | -0.0525667 |
| FTL | ferritin, light polypeptide | -0.0521175 |
| RPL19 | ribosomal protein L19 | -0.0519166 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0515041 |
| UBC | ubiquitin C | -0.0510406 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0494462 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0487192 |
| ACTG1 | actin gamma 1 | -0.047412 |
| LAMA4 | laminin, alpha 4 | -0.0461843 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0461825 |
| APOL1 | apolipoprotein L, 1 | -0.0453205 |
| RPS23 | ribosomal protein S23 | -0.0451877 |
| RPS29 | ribosomal protein S29 | -0.0449669 |
| DTNA | dystrobrevin, alpha | -0.0446998 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0442073 |
| MT1X | metallothionein 1X | -0.0421218 |
| S100A10 | S100 calcium binding protein A10 | -0.04205 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0413301 |
| SMAD3 | SMAD family member 3 | -0.0409801 |
| B2M | beta-2-microglobulin | -0.0398998 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0397629 |
| S100A6 | S100 calcium binding protein A6 | -0.0392129 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0391989 |
| DSG2 | desmoglein 2 | -0.0381718 |
| LDHA | lactate dehydrogenase A | -0.0378463 |
| CMIP | c-Maf inducing protein | -0.0378227 |
| PLAU | plasminogen activator, urokinase | -0.0375787 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0371678 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0368864 |
| ANXA2 | annexin A2 | -0.0365809 |
| CD47 | CD47 molecule | -0.0364364 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0362738 |
| TGM2 | transglutaminase 2 | -0.0356533 |
| HLA-B | major histocompatibility complex, class I, B | -0.0351578 |
| TXNIP | thioredoxin interacting protein | -0.0351489 |
| TPM4 | tropomyosin 4 | -0.0349221 |
| RPS19 | ribosomal protein S19 | -0.0342554 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.034254 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0340015 |
| RPS21 | ribosomal protein S21 | -0.033972 |
| RPLP1 | ribosomal protein, large, P1 | -0.0336687 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0334108 |
| NUMB | numb homolog (Drosophila) | -0.0332345 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.033198 |
| RPL23 | ribosomal protein L23 | -0.0324533 |
| RPS25 | ribosomal protein S25 | -0.032425 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0323175 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.032065 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0320562 |
| ATXN1 | ataxin 1 | -0.0320242 |
| VIM | vimentin | -0.0318045 |
| MCL1 | myeloid cell leukemia 1 | -0.0309162 |
| PFKP | phosphofructokinase, platelet | -0.0308835 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0308625 |
| PRKCA | protein kinase C, alpha | -0.030751 |
| PARD3 | par-3 family cell polarity regulator | -0.029462 |
| HMGA2 | high mobility group AT-hook 2 | -0.0294473 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0293576 |
| LCN2 | lipocalin 2 | -0.0292732 |
| ASPH | aspartate beta-hydroxylase | -0.029269 |
| HDAC9 | histone deacetylase 9 | -0.029242 |
| CDK6 | cyclin-dependent kinase 6 | -0.0292166 |
| FOSL1 | FOS-like antigen 1 | -0.02913 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0287779 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0279914 |
| PGK1 | phosphoglycerate kinase 1 | -0.0279624 |
| RPS24 | ribosomal protein S24 | -0.0278333 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.027826 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0277847 |
| ITGA6 | integrin, alpha 6 | -0.0277119 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0274549 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0271958 |
| CSTB | cystatin B (stefin B) | -0.0271138 |
| VEGFA | vascular endothelial growth factor A | -0.0268641 |
| RPL11 | ribosomal protein L11 | -0.0266896 |
| TAGLN2 | transgelin 2 | -0.0266135 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0265754 |
| RPL28 | ribosomal protein L28 | -0.0265273 |
| ACTN4 | actinin, alpha 4 | -0.0259309 |
| ANXA4 | annexin A4 | -0.0256374 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0251842 |
| SFTPA2 | surfactant protein A2 | -0.0251714 |
