| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nafamostat (mesylate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.122996 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0573243 |
| RPL4 | ribosomal protein L4 | 0.0498056 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0479653 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0472295 |
| FNBP1 | formin binding protein 1 | 0.0415777 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.041234 |
| OGA | O-GlcNAcase | 0.0390092 |
| PHF3 | PHD finger protein 3 | 0.0388021 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0361784 |
| HMGB2 | high mobility group box 2 | 0.0307753 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0290313 |
| RPS2 | ribosomal protein S2 | 0.0287469 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.027844 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0275379 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0271618 |
| ZNF292 | zinc finger protein 292 | 0.025174 |
| ADAR | adenosine deaminase, RNA-specific | 0.0250477 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0249799 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0249294 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0246421 |
| DST | dystonin | 0.0244074 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0235528 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0231265 |
| RUNX1 | runt-related transcription factor 1 | 0.0217631 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0215599 |
| RAB30 | RAB30, member RAS oncogene family | 0.0215479 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0213333 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0207562 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0206708 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.020557 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0204217 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0202247 |
| MYO9A | myosin IXA | 0.0199103 |
| ENO1 | enolase 1, (alpha) | 0.0197849 |
| GPC5 | glypican 5 | 0.0196873 |
| FNIP1 | folliculin interacting protein 1 | 0.0196726 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0194531 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0192883 |
| ATM | ATM serine/threonine kinase | 0.0192687 |
| HAND2 | heart and neural crest derivatives expressed 2 | 0.0192201 |
| PLPP1 | phospholipid phosphatase 1 | 0.0192055 |
| CENPF | centromere protein F, 350/400kDa | 0.0190418 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0189619 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0186132 |
| ZNF331 | zinc finger protein 331 | 0.0184792 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0182497 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0182255 |
| YEATS2 | YEATS domain containing 2 | 0.0179197 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0177987 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0177677 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0172715 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 | 0.0165899 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0165272 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0164284 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0163797 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.016115 |
| SP100 | SP100 nuclear antigen | 0.0158456 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0158228 |
| SEC24B | SEC24 family member B | 0.0157955 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0157716 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0155999 |
| KIF14 | kinesin family member 14 | 0.0155493 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0154726 |
| VGLL4 | vestigial-like family member 4 | 0.0154076 |
| TAPBP | TAP binding protein (tapasin) | 0.015271 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0151932 |
| PRPF3 | pre-mRNA processing factor 3 | 0.0151307 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0149493 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0149076 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0148996 |
| RNF145 | ring finger protein 145 | 0.0148445 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0148072 |
| PLAT | plasminogen activator, tissue | 0.0147574 |
| YTHDC1 | YTH domain containing 1 | 0.014714 |
| PLSCR1 | phospholipid scramblase 1 | 0.014688 |
| RPS15A | ribosomal protein S15a | 0.0146323 |
| NKTR | natural killer cell triggering receptor | 0.0146089 |
| MKI67 | marker of proliferation Ki-67 | 0.0145226 |
| ZNF106 | zinc finger protein 106 | 0.0144527 |
| RBM39 | RNA binding motif protein 39 | 0.014374 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0141689 |
| KIAA1217 | KIAA1217 | 0.0141507 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0141195 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0140523 |
| HAS2 | hyaluronan synthase 2 | 0.0140492 |
| BDKRB2 | bradykinin receptor B2 | 0.0140488 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0139726 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.013928 |
| FOXN3 | forkhead box N3 | 0.0139057 |
| MMP2 | matrix metallopeptidase 2 | 0.0138696 |
| B2M | beta-2-microglobulin | 0.0137714 |
| DAND5 | DAN domain family member 5, BMP antagonist | 0.0137427 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0136987 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0135901 |
| JMJD1C | jumonji domain containing 1C | 0.0135272 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0133413 |
| GOLGA4 | golgin A4 | 0.0132235 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0131963 |
| SP140L | SP140 nuclear body protein-like | 0.0131932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.266704 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.234017 |
| NRG1 | neuregulin 1 | -0.200163 |
| VCL | vinculin | -0.181892 |
| LSAMP | limbic system-associated membrane protein | -0.160859 |
| EXT1 | exostosin glycosyltransferase 1 | -0.157145 |
| PRKCA | protein kinase C, alpha | -0.143892 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0926126 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0923872 |
| FMN1 | formin 1 | -0.0832448 |
| TRIB2 | tribbles pseudokinase 2 | -0.080509 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.078971 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.074774 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.071778 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0711218 |
| LPIN1 | lipin 1 | -0.0622225 |
| MSI2 | musashi RNA-binding protein 2 | -0.0597793 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0590586 |
| ZNF804A | zinc finger protein 804A | -0.0581119 |
| DTNA | dystrobrevin, alpha | -0.0540158 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0527403 |
| FRMD4A | FERM domain containing 4A | -0.0520888 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0520345 |
| PTMA | prothymosin, alpha | -0.0505294 |
| ACTG1 | actin gamma 1 | -0.0494394 |
| SYT1 | synaptotagmin I | -0.0493995 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0478402 |
| DNM3 | dynamin 3 | -0.0460799 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0454074 |
| TLE4 | transducin-like enhancer of split 4 | -0.0439206 |
| INTS6 | integrator complex subunit 6 | -0.0432674 |
| CDH13 | cadherin 13 | -0.043077 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0430437 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0430343 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0430299 |
| DPH6 | diphthamine biosynthesis 6 | -0.0424637 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0420722 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0418533 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0418311 |
| EFNA5 | ephrin-A5 | -0.0417035 |
| TPM1 | tropomyosin 1 (alpha) | -0.0415829 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0399601 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0397539 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0395971 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0393143 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0392958 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0390815 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0385153 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.038381 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0382356 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0381356 |
| EXOC4 | exocyst complex component 4 | -0.0379297 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0377095 |
| DACH2 | dachshund family transcription factor 2 | -0.0376903 |
| CRH | corticotropin releasing hormone | -0.0376713 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0374749 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0373014 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0364195 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0363825 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0363467 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0360188 |
| BBX | bobby sox homolog (Drosophila) | -0.0359331 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0357085 |
| CADM2 | cell adhesion molecule 2 | -0.0353801 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0349863 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0346753 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0341314 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0338406 |
| MEIS2 | Meis homeobox 2 | -0.0337788 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0336406 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.033558 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0335143 |
| THBS1 | thrombospondin 1 | -0.033478 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0332319 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0328671 |
| CDK12 | cyclin-dependent kinase 12 | -0.0325327 |
| BPTF | bromodomain PHD finger transcription factor | -0.0323976 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0322894 |
| RAD51B | RAD51 paralog B | -0.0315723 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0315154 |
| HDLBP | high density lipoprotein binding protein | -0.0313201 |
| NREP | neuronal regeneration related protein | -0.0312674 |
| RCOR1 | REST corepressor 1 | -0.0312665 |
| CTBP2 | C-terminal binding protein 2 | -0.0310738 |
| FNDC3A | fibronectin type III domain containing 3A | -0.030817 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0308086 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0307172 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0305707 |
| PTK2 | protein tyrosine kinase 2 | -0.0305454 |
| CUX1 | cut-like homeobox 1 | -0.0304144 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.0300261 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.029898 |
| NF1 | neurofibromin 1 | -0.0294524 |
| MCL1 | myeloid cell leukemia 1 | -0.0290039 |
| PKM | pyruvate kinase, muscle | -0.0289983 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0289815 |
| QKI | QKI, KH domain containing, RNA binding | -0.028936 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0288835 |
| LRRC7 | leucine rich repeat containing 7 | -0.0285741 |
| STK38L | serine/threonine kinase 38 like | -0.0281908 |
