| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.158081 |
| LMO7 | LIM domain 7 | 0.0553284 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0474989 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0458782 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0389228 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0387706 |
| RBM39 | RNA binding motif protein 39 | 0.0377201 |
| RPS6 | ribosomal protein S6 | 0.0375193 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0368586 |
| CALR | calreticulin | 0.0330995 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0327898 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0325914 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0320203 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0311427 |
| RPL12 | ribosomal protein L12 | 0.0302576 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0295845 |
| NUCB2 | nucleobindin 2 | 0.0291294 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0289583 |
| EHF | ets homologous factor | 0.028456 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0277304 |
| EGR1 | early growth response 1 | 0.0273954 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0269643 |
| IRF1 | interferon regulatory factor 1 | 0.026859 |
| GOLGA4 | golgin A4 | 0.0265325 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0261463 |
| MYO1E | myosin IE | 0.0253564 |
| RPLP1 | ribosomal protein, large, P1 | 0.0249064 |
| NDRG1 | N-myc downstream regulated 1 | 0.0245459 |
| OGA | O-GlcNAcase | 0.0239998 |
| CENPF | centromere protein F, 350/400kDa | 0.023237 |
| RNF43 | ring finger protein 43 | 0.0230751 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0226022 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0225587 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0224017 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0223414 |
| EZR | ezrin | 0.0221851 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0220038 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0209691 |
| HDLBP | high density lipoprotein binding protein | 0.0205277 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0201988 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0201084 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.019781 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.01978 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0190629 |
| MKI67 | marker of proliferation Ki-67 | 0.0190219 |
| CCNL1 | cyclin L1 | 0.0189562 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0188361 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0187954 |
| SEC24D | SEC24 family member D | 0.0185267 |
| HYOU1 | hypoxia up-regulated 1 | 0.0181068 |
| CALU | calumenin | 0.0178943 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0178673 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0175911 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.017556 |
| RPS8 | ribosomal protein S8 | 0.0174738 |
| SRP54 | signal recognition particle 54kDa | 0.0170459 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0168213 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0167612 |
| DSPP | dentin sialophosphoprotein | 0.0166318 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0165603 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0164637 |
| ANXA1 | annexin A1 | 0.0164572 |
| ENO1 | enolase 1, (alpha) | 0.0163534 |
| RPL4 | ribosomal protein L4 | 0.016155 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0157301 |
| RPL26 | ribosomal protein L26 | 0.0155815 |
| MORF4L2 | mortality factor 4 like 2 | 0.0154428 |
| RUNX1 | runt-related transcription factor 1 | 0.0153725 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0151806 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 0.0150956 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0150289 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.015028 |
| SSR1 | signal sequence receptor, alpha | 0.0149195 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0147944 |
| RPS27 | ribosomal protein S27 | 0.014787 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0147378 |
| ZNF395 | zinc finger protein 395 | 0.0147121 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0146903 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0146243 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0146217 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0145673 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0144859 |
| PGM3 | phosphoglucomutase 3 | 0.0144288 |
| UBAP1 | ubiquitin associated protein 1 | 0.0144186 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0142409 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0141618 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0141105 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0140497 |
| RPN2 | ribophorin II | 0.013955 |
| AGR2 | anterior gradient 2 | 0.0139496 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0136906 |
| TMF1 | TATA element modulatory factor 1 | 0.013591 |
| USP3 | ubiquitin specific peptidase 3 | 0.0134166 |
| RPS19 | ribosomal protein S19 | 0.0133997 |
| PER2 | period circadian clock 2 | 0.0132146 |
| HMGB2 | high mobility group box 2 | 0.013188 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0130743 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0129726 |
| TFG | TRK-fused gene | 0.0129686 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0129064 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.191481 |
| RNF213 | ring finger protein 213 | -0.114066 |
| LYZ | lysozyme | -0.110927 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.102356 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.096021 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0864118 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0852303 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0845794 |
| MX1 | MX dynamin-like GTPase 1 | -0.0825998 |
| RIGI | RNA sensor RIG-I | -0.0814836 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.075185 |
| XAF1 | XIAP associated factor 1 | -0.0706401 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0705152 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0702906 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0672871 |
| MX2 | MX dynamin-like GTPase 2 | -0.0671487 |
| NPSR1 | neuropeptide S receptor 1 | -0.0662966 |
| PRKCA | protein kinase C, alpha | -0.0605382 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0575931 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0572064 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0569529 |
| SP100 | SP100 nuclear antigen | -0.0548803 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0547569 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0544049 |
| ITGA6 | integrin, alpha 6 | -0.0523803 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0516618 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.05087 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0499821 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0496744 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0496603 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0493717 |
| SSH2 | slingshot protein phosphatase 2 | -0.0472917 |
| MSI2 | musashi RNA-binding protein 2 | -0.0464797 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0461609 |
| SPATA13 | spermatogenesis associated 13 | -0.0453017 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0445889 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0442108 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0430691 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0428324 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.042403 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0393621 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0387645 |
| RAD51B | RAD51 paralog B | -0.0375597 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0361675 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0361659 |
| ERBIN | erbb2 interacting protein | -0.0357629 |
| ATP11A | ATPase, class VI, type 11A | -0.03525 |
| LAMA4 | laminin, alpha 4 | -0.0349638 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0349075 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0348563 |
| ACTG1 | actin gamma 1 | -0.0345894 |
| PERP | PERP, TP53 apoptosis effector | -0.0345183 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0341861 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0341381 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0330455 |
| TMC5 | transmembrane channel-like 5 | -0.0330266 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0327636 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0320969 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0318608 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.031603 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0314722 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0313982 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0312353 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0310673 |
| APOL1 | apolipoprotein L, 1 | -0.0310217 |
| PTGR1 | prostaglandin reductase 1 | -0.0309567 |
| MUC20 | mucin 20, cell surface associated | -0.0308442 |
| TFRC | transferrin receptor | -0.0308158 |
| PGK1 | phosphoglycerate kinase 1 | -0.0302985 |
| LCN2 | lipocalin 2 | -0.0302448 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0301823 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0301054 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0294853 |
| FMN1 | formin 1 | -0.0294837 |
| ANXA4 | annexin A4 | -0.0293996 |
| ETV6 | ets variant 6 | -0.0291436 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0288899 |
| PMP22 | peripheral myelin protein 22 | -0.0286407 |
| MAP7 | microtubule-associated protein 7 | -0.0282998 |
| POF1B | premature ovarian failure, 1B | -0.0281693 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0280149 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0279316 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0278294 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0277557 |
| TAOK3 | TAO kinase 3 | -0.0275061 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0268458 |
| DGKH | diacylglycerol kinase, eta | -0.0267954 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0266711 |
| ATP10B | ATPase, class V, type 10B | -0.0266594 |
| ANXA2 | annexin A2 | -0.0260622 |
| NF1 | neurofibromin 1 | -0.026041 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0258187 |
| ABLIM1 | actin binding LIM protein 1 | -0.0257048 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.025683 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0256038 |
| ZNF609 | zinc finger protein 609 | -0.025551 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0255294 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0254109 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0251133 |
| PRKCE | protein kinase C, epsilon | -0.0249179 |
