| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0639991 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0638688 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.047744 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0422328 |
| OGA | O-GlcNAcase | 0.0413733 |
| RPL4 | ribosomal protein L4 | 0.0401956 |
| GOLGA4 | golgin A4 | 0.0365115 |
| PTMA | prothymosin, alpha | 0.0360262 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0346845 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0334423 |
| RBM39 | RNA binding motif protein 39 | 0.031981 |
| SPAG9 | sperm associated antigen 9 | 0.0318475 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0267546 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0263574 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0260005 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0253149 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0232185 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0221792 |
| RPS2 | ribosomal protein S2 | 0.0217474 |
| ZNF292 | zinc finger protein 292 | 0.0213127 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0211983 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0207535 |
| EGR1 | early growth response 1 | 0.0206347 |
| PRRC2C | proline-rich coiled-coil 2C | 0.020173 |
| CD109 | CD109 molecule | 0.0196752 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.019426 |
| FAM13A | family with sequence similarity 13, member A | 0.019324 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0192093 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.018617 |
| NUP58 | nucleoporin 58 | 0.0185777 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0183559 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0182701 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0180484 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0178423 |
| TMF1 | TATA element modulatory factor 1 | 0.0175029 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0173793 |
| DUSP6 | dual specificity phosphatase 6 | 0.0170069 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.016607 |
| RPS18 | ribosomal protein S18 | 0.0163232 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0160343 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0159374 |
| NGLY1 | N-glycanase 1 | 0.0156179 |
| IRS2 | insulin receptor substrate 2 | 0.0151792 |
| ZNF148 | zinc finger protein 148 | 0.0149472 |
| RTN4 | reticulon 4 | 0.0146824 |
| MATR3 | matrin 3 | 0.0145982 |
| RNF220 | ring finger protein 220 | 0.0145311 |
| LOX | lysyl oxidase | 0.01453 |
| SYAP1 | synapse associated protein 1 | 0.0144777 |
| USP3 | ubiquitin specific peptidase 3 | 0.0144051 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0141802 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 | 0.0141494 |
| PER1 | period circadian clock 1 | 0.014106 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0140533 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0140399 |
| RBM25 | RNA binding motif protein 25 | 0.0139437 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0137733 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0134555 |
| SRP54 | signal recognition particle 54kDa | 0.0134249 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0132973 |
| YBX3 | Y box binding protein 3 | 0.0132065 |
| WDR45B | WD repeat domain 45B | 0.0132048 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0131684 |
| TXNIP | thioredoxin interacting protein | 0.0129783 |
| JUN | jun proto-oncogene | 0.0128825 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0127902 |
| ANLN | anillin, actin binding protein | 0.0127351 |
| FOXO3 | forkhead box O3 | 0.0126673 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0124614 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0124288 |
| RNF149 | ring finger protein 149 | 0.0123327 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0122958 |
| ARRDC3 | arrestin domain containing 3 | 0.0122869 |
| EZR | ezrin | 0.0122687 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0121662 |
| SGO2 | shugoshin 2 | 0.0121494 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0120786 |
| RPS12 | ribosomal protein S12 | 0.0119898 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0118701 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0117149 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0116502 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0116275 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0114327 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0112991 |
| RPL14 | ribosomal protein L14 | 0.0110562 |
| MT2A | metallothionein 2A | 0.0110557 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.010924 |
| KLF6 | Kruppel-like factor 6 | 0.0108638 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0107506 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0107132 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0106283 |
| CCNL1 | cyclin L1 | 0.0105845 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.010384 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0103577 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.0103438 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0103169 |
| ZNF654 | zinc finger protein 654 | 0.0102237 |
| NOP58 | NOP58 ribonucleoprotein | 0.0101215 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0101204 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0101033 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.224595 |
| CDH13 | cadherin 13 | -0.186478 |
| FN1 | fibronectin 1 | -0.180355 |
| COL5A1 | collagen, type V, alpha 1 | -0.170561 |
| VIM | vimentin | -0.161658 |
| EXT1 | exostosin glycosyltransferase 1 | -0.147526 |
| ASPH | aspartate beta-hydroxylase | -0.140211 |
| COL6A1 | collagen, type VI, alpha 1 | -0.135321 |
| NAV1 | neuron navigator 1 | -0.133849 |
| HMGA2 | high mobility group AT-hook 2 | -0.122525 |
| NDRG1 | N-myc downstream regulated 1 | -0.117631 |
| COL6A3 | collagen, type VI, alpha 3 | -0.114533 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.11368 |
| MYO10 | myosin X | -0.110573 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.102596 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0976872 |
| IGF2 | insulin-like growth factor 2 | -0.0936354 |
| AHNAK | AHNAK nucleoprotein | -0.0861524 |
| CD44 | CD44 molecule (Indian blood group) | -0.0834599 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.083427 |
| GLIS3 | GLIS family zinc finger 3 | -0.0815926 |
| RAI14 | retinoic acid induced 14 | -0.074934 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0741894 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0721897 |
| DIAPH2 | diaphanous-related formin 2 | -0.0669087 |
| ACTG1 | actin gamma 1 | -0.0668986 |
| CLMP | CXADR-like membrane protein | -0.0666793 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.066458 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0620783 |
| DST | dystonin | -0.0615527 |
| ATXN1 | ataxin 1 | -0.0600066 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.059591 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0588158 |
| ANXA2 | annexin A2 | -0.0587523 |
| LAMB3 | laminin, beta 3 | -0.0569472 |
| TMSB10 | thymosin beta 10 | -0.0562531 |
| PTK2 | protein tyrosine kinase 2 | -0.0540979 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0523034 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0518669 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0510492 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0504121 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0502342 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0483586 |
| FMN1 | formin 1 | -0.0471798 |
| EGFR | epidermal growth factor receptor | -0.0468801 |
| FRMD4A | FERM domain containing 4A | -0.0466575 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0464854 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.046173 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0458128 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0447635 |
| PGK1 | phosphoglycerate kinase 1 | -0.044747 |
| DTNA | dystrobrevin, alpha | -0.0436798 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0433726 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0428402 |
| RAD51B | RAD51 paralog B | -0.0418044 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0417122 |
| TPM1 | tropomyosin 1 (alpha) | -0.0417011 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0412119 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0402495 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0402176 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0395982 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0395542 |
| PRKCA | protein kinase C, alpha | -0.0384933 |
| KIAA1549L | KIAA1549-like | -0.0383857 |
| CCDC91 | coiled-coil domain containing 91 | -0.0380594 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0374988 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0374249 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0373126 |
| VCL | vinculin | -0.0370131 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0369271 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0367591 |
| NAV3 | neuron navigator 3 | -0.0360271 |
| RRM2 | ribonucleotide reductase M2 | -0.0359895 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0354848 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0354773 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0353187 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0351663 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0346808 |
| COL1A1 | collagen, type I, alpha 1 | -0.0343345 |
| CUX1 | cut-like homeobox 1 | -0.0342155 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.03392 |
| MAP1B | microtubule-associated protein 1B | -0.0338802 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0326158 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0324832 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0323528 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0314369 |
| CDK6 | cyclin-dependent kinase 6 | -0.0312677 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0311359 |
| INTS6 | integrator complex subunit 6 | -0.0310838 |
| WWOX | WW domain containing oxidoreductase | -0.0310704 |
| ATG7 | autophagy related 7 | -0.0309258 |
| MSN | moesin | -0.0308774 |
| PRSS23 | protease, serine, 23 | -0.0308543 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0307289 |
| TENM2 | teneurin transmembrane protein 2 | -0.0307094 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0306734 |
| CFAP20DC | CFAP20 domain containing | -0.0305188 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0305085 |
| HMGA1 | high mobility group AT-hook 1 | -0.0300469 |
| TPM4 | tropomyosin 4 | -0.0298803 |
