| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.138529 |
| LMO7 | LIM domain 7 | 0.119045 |
| RPL4 | ribosomal protein L4 | 0.098139 |
| TJP1 | tight junction protein 1 | 0.0887793 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0836403 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0685921 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0644239 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0635256 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0620474 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0580758 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0573898 |
| DST | dystonin | 0.0567338 |
| RBM39 | RNA binding motif protein 39 | 0.0554676 |
| VCL | vinculin | 0.0550332 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0549307 |
| ACTN4 | actinin, alpha 4 | 0.0538917 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0538888 |
| LAMA4 | laminin, alpha 4 | 0.0535074 |
| SMAD3 | SMAD family member 3 | 0.0527694 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0501491 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0498142 |
| EZR | ezrin | 0.049704 |
| BCL2L1 | BCL2-like 1 | 0.0487681 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0487529 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0483424 |
| CTBP2 | C-terminal binding protein 2 | 0.0476933 |
| KRT20 | keratin 20, type I | 0.0475838 |
| RPS2 | ribosomal protein S2 | 0.047461 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.046826 |
| MYO1E | myosin IE | 0.0463258 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0463159 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0454035 |
| ETV6 | ets variant 6 | 0.0452034 |
| NTN4 | netrin 4 | 0.0451154 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.044438 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0429307 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0421978 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0419528 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0409259 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0409079 |
| POF1B | premature ovarian failure, 1B | 0.0402223 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0402214 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0402043 |
| ASPH | aspartate beta-hydroxylase | 0.0397934 |
| FLNB | filamin B, beta | 0.0393864 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0392714 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0388429 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0383506 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0381337 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0375788 |
| AREG | amphiregulin | 0.037573 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0374953 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0374779 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0373665 |
| MYO6 | myosin VI | 0.0366577 |
| EGR1 | early growth response 1 | 0.0349269 |
| GOLGB1 | golgin B1 | 0.0349176 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0336786 |
| HDLBP | high density lipoprotein binding protein | 0.0332175 |
| KRT18 | keratin 18, type I | 0.0329463 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0324267 |
| LIMA1 | LIM domain and actin binding 1 | 0.0324133 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0322995 |
| STK24 | serine/threonine kinase 24 | 0.0322339 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.032161 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0320321 |
| RPS6 | ribosomal protein S6 | 0.0314608 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0311936 |
| JUN | jun proto-oncogene | 0.0311799 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0310806 |
| SLC38A1 | solute carrier family 38, member 1 | 0.030695 |
| WWC1 | WW and C2 domain containing 1 | 0.0303071 |
| TMC5 | transmembrane channel-like 5 | 0.0302669 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.030244 |
| HKDC1 | hexokinase domain containing 1 | 0.0301547 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0300156 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0298251 |
| RNF213 | ring finger protein 213 | 0.0295844 |
| DSPP | dentin sialophosphoprotein | 0.0292316 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0291489 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0291422 |
| EXOC4 | exocyst complex component 4 | 0.0286923 |
| SGMS2 | sphingomyelin synthase 2 | 0.0284453 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.028276 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0276742 |
| PRRC2C | proline-rich coiled-coil 2C | 0.027634 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0273102 |
| ANKRD11 | ankyrin repeat domain 11 | 0.027287 |
| RPS12 | ribosomal protein S12 | 0.0272409 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0270102 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0266922 |
| SEPTIN9 | septin 9 | 0.0265696 |
| CAPN8 | calpain 8 | 0.0264056 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0263657 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0260876 |
| PLEC | plectin | 0.0260137 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0260023 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0258009 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.025412 |
| MYOF | myoferlin | 0.0254014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.163966 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0954164 |
| POTEF | POTE ankyrin domain family, member F | -0.0543039 |
| FTL | ferritin, light polypeptide | -0.0501699 |
| LDHA | lactate dehydrogenase A | -0.0457748 |
| HMGA1 | high mobility group AT-hook 1 | -0.0381442 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.037218 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0336067 |
| FAM13A | family with sequence similarity 13, member A | -0.0335095 |
| USP3 | ubiquitin specific peptidase 3 | -0.0324276 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0276406 |
| RPL21 | ribosomal protein L21 | -0.0274624 |
| ARF4 | ADP-ribosylation factor 4 | -0.0270492 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0266961 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0264487 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0262168 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0257779 |
| TMSB10 | thymosin beta 10 | -0.0255502 |
| NUP58 | nucleoporin 58 | -0.0252165 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0251685 |
| RNF145 | ring finger protein 145 | -0.0242337 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0240879 |
| GOLGA4 | golgin A4 | -0.0239905 |
| VEGFA | vascular endothelial growth factor A | -0.0232228 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0232028 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0223301 |
| DSTN | destrin (actin depolymerizing factor) | -0.022283 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0221695 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0220815 |
| YBX1 | Y box binding protein 1 | -0.021215 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0212142 |
| ZFP36 | ZFP36 ring finger protein | -0.021007 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0209289 |
| LNX2 | ligand of numb-protein X 2 | -0.0208074 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0206198 |
| RPS11 | ribosomal protein S11 | -0.020537 |
| LYZ | lysozyme | -0.0204585 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.020055 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.019864 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0197709 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0195404 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0194303 |
| HELZ | helicase with zinc finger | -0.0194113 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0193696 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0191915 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0188893 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.018862 |
| ZFR | zinc finger RNA binding protein | -0.0188466 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0184761 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0182681 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0182509 |
| ANLN | anillin, actin binding protein | -0.0182009 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0181618 |
| WDR45B | WD repeat domain 45B | -0.0181424 |
| TMEM165 | transmembrane protein 165 | -0.017764 |
| HMGB1 | high mobility group box 1 | -0.0175855 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.017524 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0175084 |
| PKM | pyruvate kinase, muscle | -0.0174204 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0174161 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.017339 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -0.0171275 |
| PCBP2 | poly(rC) binding protein 2 | -0.0170955 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0170537 |
| H1-0 | H1.0 linker histone | -0.0170344 |
| PREPL | prolyl endopeptidase-like | -0.0169751 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0168999 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0168766 |
| MORF4L2 | mortality factor 4 like 2 | -0.0168706 |
| YAP1 | Yes-associated protein 1 | -0.0166546 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0164892 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0163369 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0161152 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0160974 |
| TSPAN3 | tetraspanin 3 | -0.0160444 |
| DERL1 | derlin 1 | -0.0160365 |
| PTEN | phosphatase and tensin homolog | -0.0160217 |
| HBP1 | HMG-box transcription factor 1 | -0.0159956 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0159041 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0158413 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0156937 |
| BRD2 | bromodomain containing 2 | -0.0156736 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0156521 |
| RPS23 | ribosomal protein S23 | -0.0155824 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0155816 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0154321 |
| PGK1 | phosphoglycerate kinase 1 | -0.0154218 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | -0.0153471 |
| RHOA | ras homolog family member A | -0.0151681 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.015124 |
| RPL27A | ribosomal protein L27a | -0.0151169 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0150983 |
| LPIN2 | lipin 2 | -0.0150565 |
| CCNI | cyclin I | -0.0149534 |
| HOXB3 | homeobox B3 | -0.0149335 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0148873 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0148566 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0147177 |
| PFKP | phosphofructokinase, platelet | -0.0146622 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0146291 |
