| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.139553 |
| RPS12 | ribosomal protein S12 | 0.13169 |
| GPC3 | glypican 3 | 0.11695 |
| MT2A | metallothionein 2A | 0.114482 |
| RBM39 | RNA binding motif protein 39 | 0.11364 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.113369 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.107507 |
| RPL4 | ribosomal protein L4 | 0.107291 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.102839 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.102687 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0934372 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0927311 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0925584 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0923635 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0898353 |
| RPS8 | ribosomal protein S8 | 0.089045 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0889014 |
| RPL37A | ribosomal protein L37a | 0.0771255 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.076939 |
| RPL31 | ribosomal protein L31 | 0.0737432 |
| RPL12 | ribosomal protein L12 | 0.0737212 |
| AHSG | alpha-2-HS-glycoprotein | 0.0691263 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0678669 |
| ENO1 | enolase 1, (alpha) | 0.0673107 |
| RPL5 | ribosomal protein L5 | 0.0663497 |
| RPL26 | ribosomal protein L26 | 0.0657447 |
| RPLP1 | ribosomal protein, large, P1 | 0.0656475 |
| RPL11 | ribosomal protein L11 | 0.0645002 |
| RPS3 | ribosomal protein S3 | 0.0642239 |
| RPS27A | ribosomal protein S27a | 0.0628551 |
| RBM25 | RNA binding motif protein 25 | 0.0624727 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0622281 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0602166 |
| RPL35A | ribosomal protein L35a | 0.0587186 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0579332 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.057717 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0564856 |
| FTL | ferritin, light polypeptide | 0.0550026 |
| RRBP1 | ribosome binding protein 1 | 0.054323 |
| RPL9 | ribosomal protein L9 | 0.0540129 |
| PTMA | prothymosin, alpha | 0.0533673 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0532258 |
| DSPP | dentin sialophosphoprotein | 0.0531832 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0508201 |
| RPL34 | ribosomal protein L34 | 0.0499554 |
| RACK1 | receptor for activated C kinase 1 | 0.0497108 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0477539 |
| RPS19 | ribosomal protein S19 | 0.0458951 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0457937 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0453492 |
| BCL2L1 | BCL2-like 1 | 0.0452052 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0449298 |
| RPS14 | ribosomal protein S14 | 0.0440157 |
| RPS2 | ribosomal protein S2 | 0.0439292 |
| KIF5B | kinesin family member 5B | 0.0435539 |
| GOLGA4 | golgin A4 | 0.0429687 |
| RPL37 | ribosomal protein L37 | 0.0426271 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0422495 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0419119 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0415538 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0415153 |
| RPL23 | ribosomal protein L23 | 0.0408432 |
| GDF15 | growth differentiation factor 15 | 0.0407793 |
| RPLP0 | ribosomal protein, large, P0 | 0.040729 |
| APOA2 | apolipoprotein A-II | 0.0407099 |
| HLA-A | major histocompatibility complex, class I, A | 0.0406872 |
| RPS17 | ribosomal protein S17 | 0.0405337 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0404664 |
| EGR1 | early growth response 1 | 0.0403478 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0401271 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0394908 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0394853 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0390976 |
| TRIM26 | tripartite motif containing 26 | 0.0385126 |
| RPLP2 | ribosomal protein, large, P2 | 0.0384243 |
| TOP1 | topoisomerase (DNA) I | 0.0383683 |
| SET | SET nuclear proto-oncogene | 0.0382563 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0369908 |
| ITGAV | integrin, alpha V | 0.0366976 |
| EHBP1 | EH domain binding protein 1 | 0.0366721 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0362439 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0359286 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0358379 |
| TF | transferrin | 0.0357849 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0351625 |
| IER3 | immediate early response 3 | 0.0351082 |
| SELENOP | selenoprotein P | 0.0349083 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.034541 |
| RPS24 | ribosomal protein S24 | 0.0343376 |
| RPS13 | ribosomal protein S13 | 0.034023 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.033718 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0334637 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0334504 |
| APOE | apolipoprotein E | 0.0332412 |
| VCL | vinculin | 0.0331475 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0329248 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0326328 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0326236 |
| RPL30 | ribosomal protein L30 | 0.0323889 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0317838 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.21297 |
| FN1 | fibronectin 1 | -0.203174 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.187928 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0994618 |
| GPC6 | glypican 6 | -0.0977401 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0694773 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0629515 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0545237 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0474835 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0474269 |
| GSE1 | Gse1 coiled-coil protein | -0.0444116 |
| INTS6 | integrator complex subunit 6 | -0.0402323 |
| C3 | complement component 3 | -0.0391606 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0376763 |
| ATXN1 | ataxin 1 | -0.0372036 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0366178 |
| ASPH | aspartate beta-hydroxylase | -0.0363333 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0359901 |
| NDRG1 | N-myc downstream regulated 1 | -0.0354845 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0340782 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.033612 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0329366 |
| RNF213 | ring finger protein 213 | -0.0303573 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0299171 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291447 |
| RUNX1 | runt-related transcription factor 1 | -0.0286173 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0285229 |
| DTNA | dystrobrevin, alpha | -0.0272863 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0268875 |
| KIAA1217 | KIAA1217 | -0.0265849 |
| PEG3 | paternally expressed 3 | -0.0251123 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0250568 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0246958 |
| FRK | fyn-related Src family tyrosine kinase | -0.0243561 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0228019 |
| KIZ | kizuna centrosomal protein | -0.0225975 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0223293 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0221493 |
| TNS3 | tensin 3 | -0.0209873 |
| NABP1 | nucleic acid binding protein 1 | -0.0209461 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0209031 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0207592 |
| APOB | apolipoprotein B | -0.0206744 |
| H1-0 | H1.0 linker histone | -0.0202765 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0202332 |
| KIF21A | kinesin family member 21A | -0.0200695 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.019627 |
| ATP10A | ATPase, class V, type 10A | -0.0187966 |
| FILIP1L | filamin A interacting protein 1-like | -0.0185433 |
| TXNIP | thioredoxin interacting protein | -0.018529 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0184464 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0183645 |
| POTEF | POTE ankyrin domain family, member F | -0.0178607 |
| FHL2 | four and a half LIM domains 2 | -0.0178555 |
| SMAD3 | SMAD family member 3 | -0.0176962 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0176897 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0176872 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0176433 |
| PRDM2 | PR domain containing 2, with ZNF domain | -0.0174744 |
| SVIL | supervillin | -0.0173587 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.01715 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0170959 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0170435 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0169699 |
| AEBP2 | AE binding protein 2 | -0.0167891 |
| EFHD2 | EF-hand domain family, member D2 | -0.0166308 |
| ARFGEF3 | ARFGEF family member 3 | -0.016567 |
| TBCK | TBC1 domain containing kinase | -0.0159622 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0159137 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0159055 |
| SP3 | Sp3 transcription factor | -0.0156311 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0156093 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0155932 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0155141 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0154852 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0151867 |
| TFRC | transferrin receptor | -0.0151758 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.015101 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0151007 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0150957 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0149679 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0149 |
| TLE4 | transducin-like enhancer of split 4 | -0.0147971 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0146814 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0146219 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0142022 |
| SEC24A | SEC24 family member A | -0.0141799 |
| SATB2 | SATB homeobox 2 | -0.0140907 |
| RAD51B | RAD51 paralog B | -0.0140544 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0140095 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0138146 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0136466 |
| CD109 | CD109 molecule | -0.0134857 |
| FOXO3 | forkhead box O3 | -0.0134341 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0133616 |
| TOX3 | TOX high mobility group box family member 3 | -0.0132603 |
| NUMB | numb homolog (Drosophila) | -0.0132496 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0132103 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0130821 |
| RNF111 | ring finger protein 111 | -0.0127527 |
