| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | 0.179468 |
| HLA-A | major histocompatibility complex, class I, A | 0.143752 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.116862 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.094068 |
| MT2A | metallothionein 2A | 0.093321 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0927955 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0811954 |
| GOLGA4 | golgin A4 | 0.0787673 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0786025 |
| RBM39 | RNA binding motif protein 39 | 0.0749304 |
| B2M | beta-2-microglobulin | 0.0728298 |
| OSMR | oncostatin M receptor | 0.0723136 |
| TXNRD1 | thioredoxin reductase 1 | 0.0708661 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0649157 |
| PRRC2C | proline-rich coiled-coil 2C | 0.064641 |
| RBM25 | RNA binding motif protein 25 | 0.0613251 |
| RPS6 | ribosomal protein S6 | 0.0608792 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0602455 |
| RPL4 | ribosomal protein L4 | 0.0562094 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0558059 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0546202 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0545611 |
| PTK2 | protein tyrosine kinase 2 | 0.0532928 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0532079 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0523286 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0503599 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0492014 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.048931 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0469567 |
| SET | SET nuclear proto-oncogene | 0.0464166 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0461556 |
| RTN4 | reticulon 4 | 0.0460392 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0453473 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.045121 |
| MT1X | metallothionein 1X | 0.044711 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0439974 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0437063 |
| FLNB | filamin B, beta | 0.0428761 |
| RPLP2 | ribosomal protein, large, P2 | 0.0426559 |
| BCL2L1 | BCL2-like 1 | 0.0424539 |
| TPM3 | tropomyosin 3 | 0.0416048 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0409491 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0406213 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0393916 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.039241 |
| FNBP4 | formin binding protein 4 | 0.0389069 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0388919 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0387952 |
| THOC2 | THO complex 2 | 0.0369873 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0367261 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0366368 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0366093 |
| CD44 | CD44 molecule (Indian blood group) | 0.0353962 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0351911 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.034494 |
| ZNF148 | zinc finger protein 148 | 0.0340371 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0339897 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0337108 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0336288 |
| FUS | FUS RNA binding protein | 0.0335947 |
| VIM | vimentin | 0.0334335 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0328599 |
| RAI14 | retinoic acid induced 14 | 0.0325355 |
| ZNF432 | zinc finger protein 432 | 0.0325304 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0323592 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0320086 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0319396 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0319266 |
| CEP95 | centrosomal protein 95kDa | 0.0317452 |
| ATXN2 | ataxin 2 | 0.0314559 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0313474 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.031141 |
| ZNF292 | zinc finger protein 292 | 0.0309482 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0305011 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.030422 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0304004 |
| RPL26 | ribosomal protein L26 | 0.0302501 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0301753 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0301362 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0297674 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0296961 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0296449 |
| NF1 | neurofibromin 1 | 0.02962 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0295599 |
| CEP350 | centrosomal protein 350kDa | 0.0294528 |
| JMJD1C | jumonji domain containing 1C | 0.0294025 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.029206 |
| PDS5B | PDS5 cohesin associated factor B | 0.0291556 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.029041 |
| FAM120A | family with sequence similarity 120A | 0.0289814 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0289704 |
| DIAPH3 | diaphanous-related formin 3 | 0.0289681 |
| SBF2 | SET binding factor 2 | 0.0286768 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0286223 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0285256 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0283012 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.028205 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0276676 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0275326 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0275241 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.250869 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.210859 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157027 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.119661 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0980076 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0970846 |
| NDRG1 | N-myc downstream regulated 1 | -0.0895358 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0832993 |
| ANXA2 | annexin A2 | -0.0655781 |
| AHNAK | AHNAK nucleoprotein | -0.0641821 |
| INTS6 | integrator complex subunit 6 | -0.0633084 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0585265 |
| FTL | ferritin, light polypeptide | -0.058237 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0571836 |
| POTEF | POTE ankyrin domain family, member F | -0.0519964 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0495566 |
| TLE4 | transducin-like enhancer of split 4 | -0.0466252 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0455459 |
| ASPH | aspartate beta-hydroxylase | -0.0435292 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0418374 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0401989 |
| PLCB4 | phospholipase C, beta 4 | -0.0395647 |
| FSTL1 | follistatin-like 1 | -0.0391975 |
| FRMD6 | FERM domain containing 6 | -0.038692 |
| GLIS3 | GLIS family zinc finger 3 | -0.0373881 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.036329 |
| NABP1 | nucleic acid binding protein 1 | -0.0359028 |
| LDHA | lactate dehydrogenase A | -0.035677 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0352963 |
| PGK1 | phosphoglycerate kinase 1 | -0.0348089 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0337819 |
| PODXL | podocalyxin-like | -0.0331513 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0318716 |
| CAVIN1 | caveolae associated protein 1 | -0.0318705 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0286349 |
| DIPK2A | divergent protein kinase domain 2A | -0.0279709 |
| ZNF804A | zinc finger protein 804A | -0.0274006 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0265033 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0260408 |
| TMEM263 | transmembrane protein 263 | -0.02578 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0246602 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0243319 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0242725 |
| ACTG1 | actin gamma 1 | -0.0242318 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0238986 |
| AEBP2 | AE binding protein 2 | -0.0237069 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0227084 |
| CUL4B | cullin 4B | -0.0226482 |
| CAST | calpastatin | -0.0225881 |
| SULF1 | sulfatase 1 | -0.0223931 |
| PKM | pyruvate kinase, muscle | -0.0220079 |
| VCL | vinculin | -0.0218906 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0216154 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0215267 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.021411 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0206969 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0203608 |
| CLIC4 | chloride intracellular channel 4 | -0.0202729 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0201249 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0200482 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.019654 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.019515 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0192205 |
| NPPB | natriuretic peptide B | -0.0190155 |
| TGFB2 | transforming growth factor, beta 2 | -0.0189157 |
| INSIG1 | insulin induced gene 1 | -0.0187955 |
| DEK | DEK proto-oncogene | -0.0187541 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.018653 |
| ACTN4 | actinin, alpha 4 | -0.0183587 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0181919 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0180216 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.017831 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0178254 |
| RYBP | RING1 and YY1 binding protein | -0.0178197 |
| MATN2 | matrilin 2 | -0.017774 |
| EGFR | epidermal growth factor receptor | -0.0176318 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0174516 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0173141 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0172577 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0172254 |
| QKI | QKI, KH domain containing, RNA binding | -0.0168194 |
| HLA-C | major histocompatibility complex, class I, C | -0.0167156 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0166851 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0164965 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0164687 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0164581 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0164178 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0163984 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0163693 |
| RSU1 | Ras suppressor protein 1 | -0.0163416 |
| HBP1 | HMG-box transcription factor 1 | -0.0163065 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0162646 |
| TFRC | transferrin receptor | -0.0161857 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0161611 |
| E2F3 | E2F transcription factor 3 | -0.0161188 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0159924 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0159306 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0158598 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0157989 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0156272 |
