| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124953 |
| RPL4 | ribosomal protein L4 | 0.102722 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.083933 |
| EFNA5 | ephrin-A5 | 0.073606 |
| RPS2 | ribosomal protein S2 | 0.0510494 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0464561 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.040305 |
| HDAC9 | histone deacetylase 9 | 0.0389479 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0388326 |
| RBM39 | RNA binding motif protein 39 | 0.0371613 |
| DTNA | dystrobrevin, alpha | 0.036907 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0353133 |
| RPS18 | ribosomal protein S18 | 0.0339068 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0297897 |
| VCL | vinculin | 0.0292368 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.029041 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0287862 |
| OSMR | oncostatin M receptor | 0.0283318 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0277373 |
| SATB2 | SATB homeobox 2 | 0.0261417 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0258142 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0252817 |
| USP34 | ubiquitin specific peptidase 34 | 0.0247557 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0246128 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.024462 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0239645 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0235315 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0228483 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0223321 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0221019 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0220864 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0218438 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0215209 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0212923 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0212363 |
| OGA | O-GlcNAcase | 0.0211014 |
| ITSN2 | intersectin 2 | 0.021026 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0208474 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0207987 |
| RPL12 | ribosomal protein L12 | 0.0205755 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0199232 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0198134 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0197041 |
| INTS6 | integrator complex subunit 6 | 0.0196006 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0193357 |
| RPL5 | ribosomal protein L5 | 0.0192297 |
| NF1 | neurofibromin 1 | 0.0191917 |
| RPL26 | ribosomal protein L26 | 0.0186276 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.018595 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0185128 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0183444 |
| SP100 | SP100 nuclear antigen | 0.018191 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0180763 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0180694 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0180388 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0176823 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0176536 |
| SCFD1 | sec1 family domain containing 1 | 0.0173699 |
| MYOF | myoferlin | 0.0170581 |
| MYO9A | myosin IXA | 0.0168571 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.0168333 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0168217 |
| RPL14 | ribosomal protein L14 | 0.0167035 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0165324 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0161168 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0159684 |
| TOP1 | topoisomerase (DNA) I | 0.015649 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0156384 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0155635 |
| PTCHD4 | patched domain containing 4 | 0.0154019 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0153271 |
| CD163L1 | CD163 molecule-like 1 | 0.0152088 |
| MED13 | mediator complex subunit 13 | 0.0151402 |
| NEK7 | NIMA-related kinase 7 | 0.0151394 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.014975 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0149318 |
| NRDC | nardilysin convertase | 0.014874 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0148161 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0148116 |
| ETV6 | ets variant 6 | 0.0147991 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0147807 |
| ZNF638 | zinc finger protein 638 | 0.0147204 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0146086 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0144921 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0144714 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0142521 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0142518 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0141778 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0141566 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0139949 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0138802 |
| WAPL | WAPL cohesin release factor | 0.0138121 |
| BRD2 | bromodomain containing 2 | 0.0137828 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0135282 |
| TTC27 | tetratricopeptide repeat domain 27 | 0.0135143 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0135141 |
| NCOR1 | nuclear receptor corepressor 1 | 0.01349 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0134861 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0134287 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0133914 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.158974 |
| VIM | vimentin | -0.13447 |
| TMSB10 | thymosin beta 10 | -0.100409 |
| LSAMP | limbic system-associated membrane protein | -0.0809196 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0797591 |
| MMP12 | matrix metallopeptidase 12 | -0.075848 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0626842 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.061957 |
| HMGA1 | high mobility group AT-hook 1 | -0.0593659 |
| GPC6 | glypican 6 | -0.0474703 |
| CDH13 | cadherin 13 | -0.0471505 |
| NDRG1 | N-myc downstream regulated 1 | -0.0434654 |
| PKM | pyruvate kinase, muscle | -0.0417652 |
| KIAA1549L | KIAA1549-like | -0.0417367 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0416226 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0415987 |
| POTEF | POTE ankyrin domain family, member F | -0.0399824 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0399823 |
| ITGA6 | integrin, alpha 6 | -0.0399128 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0398653 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0396582 |
| MYO10 | myosin X | -0.0392236 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0392173 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0392142 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0373695 |
| MSN | moesin | -0.0373517 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0371417 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0369789 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0360117 |
| PTMA | prothymosin, alpha | -0.0355997 |
| FN1 | fibronectin 1 | -0.0353 |
| AHNAK | AHNAK nucleoprotein | -0.0341788 |
| KIAA1217 | KIAA1217 | -0.0339805 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0319397 |
| ANXA2 | annexin A2 | -0.0311117 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.030065 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0293314 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0291553 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0287704 |
| ASPH | aspartate beta-hydroxylase | -0.0285061 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0278318 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0271627 |
| TNNC1 | troponin C type 1 (slow) | -0.0270823 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0269574 |
| MCL1 | myeloid cell leukemia 1 | -0.0267336 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0267152 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0264508 |
| MT2A | metallothionein 2A | -0.0263226 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0260547 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0260021 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0257863 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0257758 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0255547 |
| CDK6 | cyclin-dependent kinase 6 | -0.02547 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0249471 |
| TPM4 | tropomyosin 4 | -0.0246579 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0246233 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0241554 |
| NTM | neurotrimin | -0.0241281 |
| PFN1 | profilin 1 | -0.0240116 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0236749 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0235902 |
| FOSL1 | FOS-like antigen 1 | -0.0233163 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0232864 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0228771 |
| CORO1C | coronin, actin binding protein, 1C | -0.0226009 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0220944 |
| PGK1 | phosphoglycerate kinase 1 | -0.0220694 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.021428 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0212848 |
| LDHA | lactate dehydrogenase A | -0.0211039 |
| CDK17 | cyclin-dependent kinase 17 | -0.021005 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0209503 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0207577 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0204639 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0204358 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0204138 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0204004 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0200155 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.019927 |
| RPS6 | ribosomal protein S6 | -0.0199 |
| TENM2 | teneurin transmembrane protein 2 | -0.0198763 |
| RPS25 | ribosomal protein S25 | -0.0197635 |
| CD109 | CD109 molecule | -0.0196082 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0193378 |
| RPS13 | ribosomal protein S13 | -0.0191652 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0187589 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0185007 |
| RPL35A | ribosomal protein L35a | -0.0183776 |
| RPS10 | ribosomal protein S10 | -0.0181589 |
| FGF5 | fibroblast growth factor 5 | -0.0178487 |
| GNAS | GNAS complex locus | -0.0171938 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.0171773 |
| RPL21 | ribosomal protein L21 | -0.016944 |
| RPL23 | ribosomal protein L23 | -0.0167445 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0166154 |
| RPS21 | ribosomal protein S21 | -0.016597 |
| KCMF1 | potassium channel modulatory factor 1 | -0.016374 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0163588 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0163545 |
