| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nafamostat (mesylate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.218581 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.185908 |
| VIM | vimentin | 0.183353 |
| RAI1 | retinoic acid induced 1 | 0.124167 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.122983 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0986751 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0856498 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0843093 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0719279 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0714472 |
| EZR | ezrin | 0.0691514 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0689698 |
| CENPF | centromere protein F, 350/400kDa | 0.066016 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0619263 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0603475 |
| TMEM41B | transmembrane protein 41B | 0.0586812 |
| RTN4 | reticulon 4 | 0.0579267 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0573446 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0544666 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0526763 |
| EREG | epiregulin | 0.0521557 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0518685 |
| MKI67 | marker of proliferation Ki-67 | 0.0512005 |
| JMJD1C | jumonji domain containing 1C | 0.050319 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0486699 |
| RPL4 | ribosomal protein L4 | 0.0484376 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0476383 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0474962 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0470741 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0451213 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0438359 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0436839 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0436563 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0431199 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0424135 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0386803 |
| CAPRIN2 | caprin family member 2 | 0.0386255 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0384289 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0378809 |
| EMP1 | epithelial membrane protein 1 | 0.0377237 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0373167 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0372176 |
| UPP1 | uridine phosphorylase 1 | 0.0362969 |
| ANGPTL4 | angiopoietin-like 4 | 0.0357227 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0354284 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0353212 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0352311 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0343195 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0342027 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0341605 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0341234 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0337402 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0333926 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0331622 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0324174 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0321948 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0314423 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0310987 |
| AHNAK | AHNAK nucleoprotein | 0.0307541 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0306636 |
| EGR1 | early growth response 1 | 0.0304292 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0304277 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.030175 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0301672 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.029703 |
| USP34 | ubiquitin specific peptidase 34 | 0.0288841 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0286312 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.028123 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0275397 |
| CDCP1 | CUB domain containing protein 1 | 0.0273486 |
| ANXA1 | annexin A1 | 0.0273055 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.027142 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0269801 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0266403 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0264572 |
| PYGB | phosphorylase, glycogen; brain | 0.0263607 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.025876 |
| CEP170 | centrosomal protein 170kDa | 0.0258064 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0256054 |
| JUN | jun proto-oncogene | 0.0255587 |
| HJURP | Holliday junction recognition protein | 0.0253554 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0253441 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0253326 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0252646 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0251642 |
| RPS18 | ribosomal protein S18 | 0.0249169 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0248669 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0240165 |
| CANX | calnexin | 0.0235611 |
| IPO7 | importin 7 | 0.0233367 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0232122 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0231356 |
| XPO1 | exportin 1 | 0.0230869 |
| WDR26 | WD repeat domain 26 | 0.0225809 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0225174 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0224873 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0223381 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0222943 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.0222782 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0222707 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.17206 |
| PTMA | prothymosin, alpha | -0.143501 |
| CADM2 | cell adhesion molecule 2 | -0.136119 |
| TMSB10 | thymosin beta 10 | -0.106399 |
| DST | dystonin | -0.102227 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0858938 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0835302 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0795928 |
| CD44 | CD44 molecule (Indian blood group) | -0.0765689 |
| TNS3 | tensin 3 | -0.0758818 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0720377 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0703679 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0682764 |
| FTL | ferritin, light polypeptide | -0.0675017 |
| RNF213 | ring finger protein 213 | -0.0650611 |
| RPL35A | ribosomal protein L35a | -0.062666 |
| EPHA4 | EPH receptor A4 | -0.061382 |
| HLA-B | major histocompatibility complex, class I, B | -0.0611064 |
| PRELID2 | PRELI domain containing 2 | -0.0603031 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0581404 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0552543 |
| EFNA5 | ephrin-A5 | -0.054035 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.049073 |
| SP100 | SP100 nuclear antigen | -0.0484527 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0478011 |
| PTK2 | protein tyrosine kinase 2 | -0.0477246 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0476313 |
| EXOC4 | exocyst complex component 4 | -0.046919 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0455325 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.045498 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0454247 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0446543 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0437555 |
| RPL36 | ribosomal protein L36 | -0.0436224 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0430363 |
| RPS19 | ribosomal protein S19 | -0.0424568 |
| HDAC9 | histone deacetylase 9 | -0.0405931 |
| RAD51B | RAD51 paralog B | -0.040125 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0391102 |
| MT2A | metallothionein 2A | -0.0381509 |
| RPL37A | ribosomal protein L37a | -0.0377492 |
| RPS8 | ribosomal protein S8 | -0.0366472 |
| AEBP2 | AE binding protein 2 | -0.0355703 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0349034 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0342854 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0338625 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0335159 |
| RPL31 | ribosomal protein L31 | -0.0334566 |
| RPS3 | ribosomal protein S3 | -0.032963 |
| RAB7A | RAB7A, member RAS oncogene family | -0.032362 |
| INTS6 | integrator complex subunit 6 | -0.0317514 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0313676 |
| EHBP1 | EH domain binding protein 1 | -0.0313023 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0308566 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0304536 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0301683 |
| B2M | beta-2-microglobulin | -0.0300857 |
| PLSCR1 | phospholipid scramblase 1 | -0.0297275 |
| GNAS | GNAS complex locus | -0.0295205 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0291937 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0291848 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0290979 |
| DPH6 | diphthamine biosynthesis 6 | -0.0287772 |
| PDE10A | phosphodiesterase 10A | -0.0286356 |
| MYOF | myoferlin | -0.0284922 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0283139 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0282012 |
| S100A9 | S100 calcium binding protein A9 | -0.0278169 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0277769 |
| RIGI | RNA sensor RIG-I | -0.0276316 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0270236 |
| RPLP1 | ribosomal protein, large, P1 | -0.0269847 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0269753 |
| RPL19 | ribosomal protein L19 | -0.0269741 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0269546 |
| RPS29 | ribosomal protein S29 | -0.0268119 |
| POTEF | POTE ankyrin domain family, member F | -0.0267524 |
| EGFR | epidermal growth factor receptor | -0.0266207 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.026305 |
| WDR27 | WD repeat domain 27 | -0.026244 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0259596 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0258202 |
| TPRG1 | tumor protein p63 regulated 1 | -0.0255387 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0244656 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0244155 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.02424 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0242005 |
| DENND1A | DENN/MADD domain containing 1A | -0.0237956 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0236342 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0236295 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0230307 |
| DNER | delta/notch-like EGF repeat containing | -0.0229475 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.022868 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0227749 |
| SMYD3 | SET and MYND domain containing 3 | -0.0227204 |
| RPS24 | ribosomal protein S24 | -0.0224605 |
| DENND5B | DENN/MADD domain containing 5B | -0.0222754 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0221349 |
| CUX1 | cut-like homeobox 1 | -0.0220387 |
| RPL35 | ribosomal protein L35 | -0.0220117 |
