| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.119777 |
| PCBP2 | poly(rC) binding protein 2 | 0.10754 |
| RBM39 | RNA binding motif protein 39 | 0.0937008 |
| GOLGA4 | golgin A4 | 0.0751035 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0738529 |
| RPL4 | ribosomal protein L4 | 0.0728066 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0487305 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0468531 |
| RPS2 | ribosomal protein S2 | 0.045298 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0409315 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0383621 |
| EZR | ezrin | 0.0367457 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0364009 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0355903 |
| OGA | O-GlcNAcase | 0.0314792 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0314577 |
| SET | SET nuclear proto-oncogene | 0.0304964 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0301641 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0301346 |
| COPA | coatomer protein complex, subunit alpha | 0.0298964 |
| PRRC2C | proline-rich coiled-coil 2C | 0.029716 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0296238 |
| FAM13A | family with sequence similarity 13, member A | 0.029455 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0283503 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0280745 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0278023 |
| JUN | jun proto-oncogene | 0.0277836 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0276924 |
| SYAP1 | synapse associated protein 1 | 0.0268211 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0261544 |
| SPAG9 | sperm associated antigen 9 | 0.0261485 |
| HELZ | helicase with zinc finger | 0.0259736 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0258846 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0257808 |
| MCL1 | myeloid cell leukemia 1 | 0.0257437 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0256335 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0253302 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0249323 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0245586 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0243404 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0240701 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0235269 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0234022 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0233559 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0232569 |
| UBC | ubiquitin C | 0.0231315 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0228608 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0228313 |
| SRP54 | signal recognition particle 54kDa | 0.0226304 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0225377 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0224139 |
| ANXA1 | annexin A1 | 0.0223581 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0221086 |
| ZNF292 | zinc finger protein 292 | 0.0220775 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.021872 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0215099 |
| ATP13A3 | ATPase type 13A3 | 0.0213211 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0210143 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.020938 |
| YBX1 | Y box binding protein 1 | 0.020844 |
| RPS18 | ribosomal protein S18 | 0.0208103 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0207222 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0205935 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0203453 |
| USP37 | ubiquitin specific peptidase 37 | 0.0202754 |
| XPO1 | exportin 1 | 0.0200985 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0200147 |
| TPR | translocated promoter region, nuclear basket protein | 0.0199053 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0198785 |
| YTHDC1 | YTH domain containing 1 | 0.0198259 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0196381 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0196201 |
| SEC24A | SEC24 family member A | 0.0191246 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0188345 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.018822 |
| ANKRD11 | ankyrin repeat domain 11 | 0.018595 |
| WAC | WW domain containing adaptor with coiled-coil | 0.018549 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0184377 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0183239 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0182831 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0181611 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0181306 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0181173 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.018116 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.017867 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0178546 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0178379 |
| RUNX2 | runt-related transcription factor 2 | 0.0178276 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0177607 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0176798 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0176762 |
| RBM33 | RNA binding motif protein 33 | 0.0176752 |
| NUP58 | nucleoporin 58 | 0.0176283 |
| NOP58 | NOP58 ribonucleoprotein | 0.0175406 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0175129 |
| RPL3 | ribosomal protein L3 | 0.0174153 |
| RCOR1 | REST corepressor 1 | 0.0173718 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.017337 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0173173 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0172924 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.421119 |
| TMSB10 | thymosin beta 10 | -0.148099 |
| VIM | vimentin | -0.148008 |
| MT2A | metallothionein 2A | -0.137737 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.124734 |
| FN1 | fibronectin 1 | -0.112007 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.10188 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0865415 |
| STC1 | stanniocalcin 1 | -0.0862438 |
| CDH13 | cadherin 13 | -0.0785637 |
| NDRG1 | N-myc downstream regulated 1 | -0.0772669 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0761251 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0753915 |
| CD44 | CD44 molecule (Indian blood group) | -0.0749635 |
| CDCP1 | CUB domain containing protein 1 | -0.0706689 |
| RPLP1 | ribosomal protein, large, P1 | -0.0705895 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0688557 |
| HMGA2 | high mobility group AT-hook 2 | -0.0673219 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0612118 |
| RPL35A | ribosomal protein L35a | -0.0599001 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0596977 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0593219 |
| FTL | ferritin, light polypeptide | -0.0585881 |
| RPS24 | ribosomal protein S24 | -0.0555275 |
| RPS21 | ribosomal protein S21 | -0.0552891 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0549 |
| GLCCI1 | glucocorticoid induced 1 | -0.0547472 |
| IER3 | immediate early response 3 | -0.0537446 |
| RPS29 | ribosomal protein S29 | -0.053456 |
| NRP1 | neuropilin 1 | -0.0533188 |
| RPL32 | ribosomal protein L32 | -0.0516053 |
| S100A10 | S100 calcium binding protein A10 | -0.0511939 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0491068 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.047757 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0476413 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.047128 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.044634 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0445671 |
| RPL34 | ribosomal protein L34 | -0.0432777 |
| MTSS1 | metastasis suppressor 1 | -0.0420176 |
| EFNA5 | ephrin-A5 | -0.0418266 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0415288 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0411322 |
| FAM20C | family with sequence similarity 20, member C | -0.0410974 |
| ATXN1 | ataxin 1 | -0.0407403 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0406529 |
| RPL31 | ribosomal protein L31 | -0.0404134 |
| DPYD | dihydropyrimidine dehydrogenase | -0.040412 |
| HMGA1 | high mobility group AT-hook 1 | -0.040205 |
| RPS19 | ribosomal protein S19 | -0.0402002 |
| RPLP0 | ribosomal protein, large, P0 | -0.039543 |
| RPLP2 | ribosomal protein, large, P2 | -0.0395008 |
| RPL11 | ribosomal protein L11 | -0.0393441 |
| PGK1 | phosphoglycerate kinase 1 | -0.038986 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0386893 |
| EXT1 | exostosin glycosyltransferase 1 | -0.038434 |
| SYT1 | synaptotagmin I | -0.0383648 |
| LOXL2 | lysyl oxidase-like 2 | -0.0380994 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0364224 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0361737 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0361434 |
| RPS23 | ribosomal protein S23 | -0.0358406 |
| LDHA | lactate dehydrogenase A | -0.0355099 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0353589 |
| RPL38 | ribosomal protein L38 | -0.0353472 |
| HLA-B | major histocompatibility complex, class I, B | -0.0339703 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0336773 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0334547 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.032624 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0325627 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0323057 |
| RPS25 | ribosomal protein S25 | -0.0320994 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0318048 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0317181 |
| RPS13 | ribosomal protein S13 | -0.0313032 |
| RPS11 | ribosomal protein S11 | -0.0311833 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0310932 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0302228 |
| PKM | pyruvate kinase, muscle | -0.0301897 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0300893 |
| OXR1 | oxidation resistance 1 | -0.029999 |
| S100A6 | S100 calcium binding protein A6 | -0.0295539 |
| PYGL | phosphorylase, glycogen, liver | -0.0290993 |
| NRG1 | neuregulin 1 | -0.0288916 |
| RPS15 | ribosomal protein S15 | -0.0287666 |
| AHNAK | AHNAK nucleoprotein | -0.0286727 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0286536 |
| RPL7A | ribosomal protein L7a | -0.0286446 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0283332 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0280714 |
| RPL28 | ribosomal protein L28 | -0.0277897 |
| CCNI | cyclin I | -0.0276909 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0274972 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0274052 |
| RPL19 | ribosomal protein L19 | -0.0273994 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0273601 |
| PARD3 | par-3 family cell polarity regulator | -0.0272529 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0265387 |
| USP34 | ubiquitin specific peptidase 34 | -0.0263413 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0263098 |
