| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.0671961 |
| RPL4 | ribosomal protein L4 | 0.0656313 |
| GDA | guanine deaminase | 0.0559142 |
| RPS2 | ribosomal protein S2 | 0.036862 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0323423 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0297994 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0286488 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0257522 |
| PRELID2 | PRELI domain containing 2 | 0.0235226 |
| RBM39 | RNA binding motif protein 39 | 0.0215914 |
| RPS18 | ribosomal protein S18 | 0.0206447 |
| DST | dystonin | 0.0205233 |
| RAD51B | RAD51 paralog B | 0.0199419 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0192792 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0191387 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0189974 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0189966 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0179496 |
| HDAC4 | histone deacetylase 4 | 0.0179354 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0178324 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.017323 |
| NTN4 | netrin 4 | 0.0172775 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.015855 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0153558 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0146817 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0145392 |
| RPS12 | ribosomal protein S12 | 0.0144333 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0143606 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0126959 |
| FRY | furry homolog (Drosophila) | 0.0126076 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0125874 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0124381 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.011861 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0111276 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0110823 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0109934 |
| GPC6 | glypican 6 | 0.0107335 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0107008 |
| RBM25 | RNA binding motif protein 25 | 0.010594 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0105468 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0103357 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0102754 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0102748 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0102499 |
| GLCCI1 | glucocorticoid induced 1 | 0.010212 |
| WWOX | WW domain containing oxidoreductase | 0.0101602 |
| KYNU | kynureninase | 0.0101238 |
| PNN | pinin, desmosome associated protein | 0.00999155 |
| HLA-A | major histocompatibility complex, class I, A | 0.00998816 |
| DHFR | dihydrofolate reductase | 0.00973179 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 | 0.00961057 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.00939417 |
| EXOC6B | exocyst complex component 6B | 0.00921721 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.00918176 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.00910674 |
| VMP1 | vacuole membrane protein 1 | 0.00904036 |
| OSMR | oncostatin M receptor | 0.00884103 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.00881512 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.00878409 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00865783 |
| FAM219A | family with sequence similarity 219, member A | 0.0086131 |
| SCFD1 | sec1 family domain containing 1 | 0.00858572 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.00850642 |
| ATXN1 | ataxin 1 | 0.00844132 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.0084357 |
| RPL14 | ribosomal protein L14 | 0.00835238 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.00835065 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00829202 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.00826188 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.00819948 |
| RPL26 | ribosomal protein L26 | 0.00819875 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00811194 |
| RPS15A | ribosomal protein S15a | 0.0080542 |
| TFCP2 | transcription factor CP2 | 0.00799077 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.00798192 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00795838 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00790212 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.00777508 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.00766515 |
| TPM3 | tropomyosin 3 | 0.00762058 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.007509 |
| INTS6 | integrator complex subunit 6 | 0.00746383 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.00741582 |
| AUTS2 | autism susceptibility candidate 2 | 0.00739282 |
| EZR | ezrin | 0.00736176 |
| MKI67 | marker of proliferation Ki-67 | 0.00730244 |
| TNRC6A | trinucleotide repeat containing 6A | 0.00721523 |
| CD109 | CD109 molecule | 0.00720746 |
| EGFR | epidermal growth factor receptor | 0.00719728 |
| WDR70 | WD repeat domain 70 | 0.0071782 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.007141 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.00710727 |
| SDC2 | syndecan 2 | 0.00710333 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00708222 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.00708213 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.00706965 |
| CAPRIN2 | caprin family member 2 | 0.00695725 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00695402 |
| OGA | O-GlcNAcase | 0.00695036 |
| TBC1D5 | TBC1 domain family, member 5 | 0.00693095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.3537 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.289391 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.174785 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.1615 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.158661 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.116527 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0934514 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0933253 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0789068 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.070745 |
| CANX | calnexin | -0.0697239 |
| TMSB10 | thymosin beta 10 | -0.0667074 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0639361 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0594104 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0584791 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0578421 |
| PGK1 | phosphoglycerate kinase 1 | -0.0561403 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0559059 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0543754 |
| VIM | vimentin | -0.0543491 |
| SPAG9 | sperm associated antigen 9 | -0.0540097 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0539638 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0521037 |
| LDHA | lactate dehydrogenase A | -0.0518897 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0513471 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0488938 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0463811 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0456448 |
| CDH13 | cadherin 13 | -0.0443444 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0439145 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0437599 |
| FTL | ferritin, light polypeptide | -0.0436321 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0417088 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0408878 |
| NCKAP5 | NCK-associated protein 5 | -0.0406027 |
| S100A6 | S100 calcium binding protein A6 | -0.0385053 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.038387 |
| RGS2 | regulator of G-protein signaling 2 | -0.0381336 |
| UBC | ubiquitin C | -0.0362316 |
| PTMA | prothymosin, alpha | -0.0359658 |
| B2M | beta-2-microglobulin | -0.0356513 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0355314 |
| STC1 | stanniocalcin 1 | -0.0351731 |
| NRCAM | neuronal cell adhesion molecule | -0.0348525 |
| PDE7B | phosphodiesterase 7B | -0.0347518 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.03458 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0339055 |
| LAMA1 | laminin, alpha 1 | -0.0335455 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0329146 |
| NCOA7 | nuclear receptor coactivator 7 | -0.032579 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0324416 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0321019 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.031455 |
| MAP7 | microtubule-associated protein 7 | -0.0312009 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0306651 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0305036 |
| MYOF | myoferlin | -0.0303575 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0301356 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0300791 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0294183 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0289965 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0288868 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0288075 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0287367 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0282683 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0282399 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0279778 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0276497 |
| RPL19 | ribosomal protein L19 | -0.0275737 |
| TBXT | T-box transcription factor T | -0.0273388 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0266443 |
| RPS23 | ribosomal protein S23 | -0.0266123 |
| S100A10 | S100 calcium binding protein A10 | -0.0265172 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0264583 |
| PALLD | palladin, cytoskeletal associated protein | -0.0261534 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0260846 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.026033 |
| GNAS | GNAS complex locus | -0.0259973 |
| LAMB1 | laminin, beta 1 | -0.0259078 |
| SFTPA2 | surfactant protein A2 | -0.0258386 |
| CTSL | cathepsin L | -0.0258213 |
| IL6 | interleukin 6 | -0.0254969 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0253515 |
| NDRG1 | N-myc downstream regulated 1 | -0.0250973 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0250861 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0250426 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0250397 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0250116 |
| WDR45B | WD repeat domain 45B | -0.0248777 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0248518 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0241666 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0241431 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0238996 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0236821 |
| MCL1 | myeloid cell leukemia 1 | -0.0236295 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0234552 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0234148 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0231158 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0227182 |
| USP3 | ubiquitin specific peptidase 3 | -0.0225846 |
