| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nafamostat (mesylate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.174757 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.162053 |
| EFNA5 | ephrin-A5 | 0.116083 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.100645 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0973495 |
| PDE10A | phosphodiesterase 10A | 0.0967853 |
| PRELID2 | PRELI domain containing 2 | 0.0955001 |
| RPS8 | ribosomal protein S8 | 0.0928356 |
| MYOF | myoferlin | 0.0928189 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.091882 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.087924 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0837692 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0742905 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0734393 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0698252 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0662546 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0654432 |
| PRKCA | protein kinase C, alpha | 0.0647475 |
| MT2A | metallothionein 2A | 0.0643992 |
| FLNB | filamin B, beta | 0.0602499 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0601235 |
| PTK2 | protein tyrosine kinase 2 | 0.0597346 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0592629 |
| JMJD1C | jumonji domain containing 1C | 0.0583686 |
| VIM | vimentin | 0.0575836 |
| OGA | O-GlcNAcase | 0.0568191 |
| CDH13 | cadherin 13 | 0.0553224 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0552091 |
| SETD5 | SET domain containing 5 | 0.0550437 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0521624 |
| VMP1 | vacuole membrane protein 1 | 0.0506615 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0492184 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0481163 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0479611 |
| BPTF | bromodomain PHD finger transcription factor | 0.0475829 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0471261 |
| ASPH | aspartate beta-hydroxylase | 0.0443388 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0442986 |
| NAV2 | neuron navigator 2 | 0.0432253 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0425081 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0418764 |
| FNDC3B | fibronectin type III domain containing 3B | 0.041365 |
| SMYD3 | SET and MYND domain containing 3 | 0.0404241 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0403607 |
| SPAG9 | sperm associated antigen 9 | 0.0402521 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0395597 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0385681 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0375868 |
| RPL5 | ribosomal protein L5 | 0.0367253 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0356094 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0354278 |
| HLA-A | major histocompatibility complex, class I, A | 0.0344332 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0340978 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0332814 |
| RUNX1 | runt-related transcription factor 1 | 0.0326065 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0317619 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0311964 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0309942 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0299374 |
| RTN4 | reticulon 4 | 0.0291985 |
| DST | dystonin | 0.0281868 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0275008 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0274271 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0273051 |
| RPL12 | ribosomal protein L12 | 0.0267577 |
| RPL15 | ribosomal protein L15 | 0.0266824 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0260687 |
| PCBP3 | poly(rC) binding protein 3 | 0.0247887 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0243912 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0238294 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0228231 |
| ENO1 | enolase 1, (alpha) | 0.0227981 |
| RPS12 | ribosomal protein S12 | 0.0219369 |
| RORA | RAR-related orphan receptor A | 0.0214247 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0207937 |
| RBM39 | RNA binding motif protein 39 | 0.0205802 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0200942 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0183128 |
| MED13 | mediator complex subunit 13 | 0.0182557 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0180451 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0171948 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0168248 |
| PKM | pyruvate kinase, muscle | 0.0166624 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0161883 |
| TMSB10 | thymosin beta 10 | 0.0143249 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0143181 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0137328 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0134244 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.01301 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0125015 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0119835 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0115766 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.011461 |
| RBM25 | RNA binding motif protein 25 | 0.0110908 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0109591 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00922625 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00888201 |
| GLIS3 | GLIS family zinc finger 3 | 0.00770296 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.00736555 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.00564989 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.173762 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.139489 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.133599 |
| EGFR | epidermal growth factor receptor | -0.109248 |
| COL5A2 | collagen, type V, alpha 2 | -0.0967723 |
| RNF213 | ring finger protein 213 | -0.0927577 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.083068 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0800076 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0798822 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0793466 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0761039 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0714737 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0711353 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0683178 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0663853 |
| LMO7 | LIM domain 7 | -0.0658942 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0658931 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0646721 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0643305 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0637809 |
| GPC6 | glypican 6 | -0.0630971 |
| MYO1E | myosin IE | -0.0608195 |
| FRMD5 | FERM domain containing 5 | -0.0597092 |
| ZNF292 | zinc finger protein 292 | -0.0590591 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0584193 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.057413 |
| CCNI | cyclin I | -0.0568657 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0566096 |
| KIF5B | kinesin family member 5B | -0.0562599 |
| RPL26 | ribosomal protein L26 | -0.0557056 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.05554 |
| DSCAM | Down syndrome cell adhesion molecule | -0.053931 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0528799 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0518839 |
| B2M | beta-2-microglobulin | -0.0514233 |
| RIGI | RNA sensor RIG-I | -0.0513938 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0507171 |
| RPLP1 | ribosomal protein, large, P1 | -0.0498968 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0497028 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0496943 |
| CALR | calreticulin | -0.0491485 |
| TXNIP | thioredoxin interacting protein | -0.0478978 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0475497 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0475466 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0475395 |
| SQSTM1 | sequestosome 1 | -0.047187 |
| SP100 | SP100 nuclear antigen | -0.0471611 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0470084 |
| STK24 | serine/threonine kinase 24 | -0.0465068 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0462753 |
| RAD51B | RAD51 paralog B | -0.0458213 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0445779 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0442494 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0439124 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0423492 |
| RPL35A | ribosomal protein L35a | -0.0420645 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0387153 |
| FAM107B | family with sequence similarity 107, member B | -0.0373652 |
| BMERB1 | bMERB domain containing 1 | -0.0354192 |
| PCBP2 | poly(rC) binding protein 2 | -0.034194 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0335848 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0295316 |
| CALU | calumenin | -0.0294215 |
| NF1 | neurofibromin 1 | -0.0293263 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0290812 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0285027 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0276281 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.027178 |
| LMNA | lamin A/C | -0.027115 |
| NABP1 | nucleic acid binding protein 1 | -0.0257992 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0251528 |
| GOLGA4 | golgin A4 | -0.0251255 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0248268 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0247521 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0246549 |
| MMP12 | matrix metallopeptidase 12 | -0.024082 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0239884 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0237457 |
| RPS6 | ribosomal protein S6 | -0.0231555 |
| PGK1 | phosphoglycerate kinase 1 | -0.0229911 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0222332 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0218374 |
| HDLBP | high density lipoprotein binding protein | -0.0212347 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0201173 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0200946 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0198991 |
| RPS24 | ribosomal protein S24 | -0.0190711 |
| CNKSR3 | CNKSR family member 3 | -0.0190495 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0177195 |
| ANO6 | anoctamin 6 | -0.0171557 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0163225 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0160859 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0159127 |
| PTMA | prothymosin, alpha | -0.0158454 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0156679 |
| NDRG1 | N-myc downstream regulated 1 | -0.0156339 |
| STAG2 | stromal antigen 2 | -0.0155843 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.015442 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0154379 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0149945 |
