| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.225697 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.202397 |
| VIM | vimentin | 0.106423 |
| RPL4 | ribosomal protein L4 | 0.102209 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.095322 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.07824 |
| TMEM41B | transmembrane protein 41B | 0.0749836 |
| VCL | vinculin | 0.0741919 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0739722 |
| CD44 | CD44 molecule (Indian blood group) | 0.0722521 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0697685 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0671417 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.06628 |
| RTN4 | reticulon 4 | 0.0640891 |
| VMP1 | vacuole membrane protein 1 | 0.0622052 |
| TXNRD1 | thioredoxin reductase 1 | 0.0594873 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0555132 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.054216 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0514138 |
| OGA | O-GlcNAcase | 0.0493552 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0486708 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0430025 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0416492 |
| JMJD1C | jumonji domain containing 1C | 0.0415411 |
| RBM39 | RNA binding motif protein 39 | 0.0412706 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.03933 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0387026 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.038189 |
| FHL2 | four and a half LIM domains 2 | 0.0375383 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0372875 |
| IPO7 | importin 7 | 0.0364841 |
| RPS2 | ribosomal protein S2 | 0.0364103 |
| OSMR | oncostatin M receptor | 0.0334647 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0332992 |
| ANGPTL4 | angiopoietin-like 4 | 0.0331407 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0326713 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0326313 |
| EGR1 | early growth response 1 | 0.0320081 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.032007 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0318635 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0316016 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0315216 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0303197 |
| RBM25 | RNA binding motif protein 25 | 0.0294593 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0288555 |
| RPS16 | ribosomal protein S16 | 0.0283056 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.02796 |
| ITGAV | integrin, alpha V | 0.0279198 |
| MAP1B | microtubule-associated protein 1B | 0.0279062 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.027898 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0278852 |
| ITGB5 | integrin, beta 5 | 0.0278704 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0270392 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0269025 |
| BCL2L1 | BCL2-like 1 | 0.0268905 |
| ARRDC3 | arrestin domain containing 3 | 0.0265159 |
| TMEM87A | transmembrane protein 87A | 0.0263179 |
| HLA-A | major histocompatibility complex, class I, A | 0.0258961 |
| SMYD3 | SET and MYND domain containing 3 | 0.0254677 |
| THOC2 | THO complex 2 | 0.0253851 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0253626 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0247554 |
| MKI67 | marker of proliferation Ki-67 | 0.0246743 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.024306 |
| SEPTIN10 | septin 10 | 0.0241978 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0241931 |
| PHF14 | PHD finger protein 14 | 0.0240778 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0239329 |
| RPS12 | ribosomal protein S12 | 0.0239149 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0238714 |
| SQSTM1 | sequestosome 1 | 0.0235766 |
| ZFP36 | ZFP36 ring finger protein | 0.0232643 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0228552 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0227715 |
| KPNB1 | karyopherin (importin) beta 1 | 0.022743 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0226969 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0223682 |
| IL6ST | interleukin 6 signal transducer | 0.0220816 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0219491 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0219245 |
| ASPH | aspartate beta-hydroxylase | 0.0216796 |
| KLF6 | Kruppel-like factor 6 | 0.0216115 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0211624 |
| FOSL1 | FOS-like antigen 1 | 0.0210722 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.021016 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0207907 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0207573 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0203749 |
| TRIM56 | tripartite motif containing 56 | 0.0200377 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0199778 |
| BMP6 | bone morphogenetic protein 6 | 0.0196909 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0196168 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0195228 |
| RPL12 | ribosomal protein L12 | 0.0194846 |
| RPL26 | ribosomal protein L26 | 0.0191789 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0190404 |
| FAM3C | family with sequence similarity 3, member C | 0.0187438 |
| ANXA2 | annexin A2 | 0.018723 |
| BMERB1 | bMERB domain containing 1 | 0.0186217 |
| GOLT1A | golgi transport 1A | 0.0185668 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.243705 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.167549 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.13428 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125453 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.10412 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0942322 |
| NAV2 | neuron navigator 2 | -0.0905122 |
| AHNAK | AHNAK nucleoprotein | -0.0832802 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0807957 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0785313 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0757355 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0721782 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0701678 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0669874 |
| FMNL2 | formin-like 2 | -0.0649105 |
| PTK2 | protein tyrosine kinase 2 | -0.0644662 |
| CTBP2 | C-terminal binding protein 2 | -0.0640378 |
| PTMA | prothymosin, alpha | -0.0633696 |
| TNS3 | tensin 3 | -0.0582318 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0577324 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0560584 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0488234 |
| HMGA1 | high mobility group AT-hook 1 | -0.044535 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0442911 |
| SPAG9 | sperm associated antigen 9 | -0.043933 |
| INTS6 | integrator complex subunit 6 | -0.0434035 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0409633 |
| PKM | pyruvate kinase, muscle | -0.0409107 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0403396 |
| HMGA2 | high mobility group AT-hook 2 | -0.0402314 |
| MORF4L2 | mortality factor 4 like 2 | -0.0399074 |
| ATG7 | autophagy related 7 | -0.0392132 |
| CMIP | c-Maf inducing protein | -0.0385441 |
| MYO10 | myosin X | -0.0379932 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0378976 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0366902 |
| CANX | calnexin | -0.0363808 |
| TMSB10 | thymosin beta 10 | -0.0357736 |
| POTEF | POTE ankyrin domain family, member F | -0.0347768 |
| NHSL1 | NHS-like 1 | -0.0339444 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0335333 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0334629 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0334537 |
| RNF220 | ring finger protein 220 | -0.0323522 |
| UBAP2 | ubiquitin associated protein 2 | -0.0321003 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0318809 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0317792 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0309524 |
| NBAS | neuroblastoma amplified sequence | -0.0302943 |
| CTSD | cathepsin D | -0.0299502 |
| TAOK1 | TAO kinase 1 | -0.0297596 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0295539 |
| DST | dystonin | -0.029208 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0283458 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0283072 |
| NUP98 | nucleoporin 98kDa | -0.027963 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0278979 |
| DIAPH2 | diaphanous-related formin 2 | -0.0277344 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0275612 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0271924 |
| CD109 | CD109 molecule | -0.0271177 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0270217 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0265321 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0264939 |
| SEPTIN9 | septin 9 | -0.0264269 |
| HM13 | histocompatibility (minor) 13 | -0.0260354 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0258213 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0253687 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0253195 |
| SMAD3 | SMAD family member 3 | -0.025191 |
| FLNA | filamin A, alpha | -0.025172 |
| FNIP1 | folliculin interacting protein 1 | -0.0251497 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.024936 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0249168 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0245781 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0245355 |
| SUCO | SUN domain containing ossification factor | -0.0244001 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0242093 |
| PRKCA | protein kinase C, alpha | -0.0240285 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0236731 |
| LDHA | lactate dehydrogenase A | -0.0235657 |
| SEC24D | SEC24 family member D | -0.0234574 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0232823 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.02297 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0229327 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0229217 |
| NEK10 | NIMA-related kinase 10 | -0.0228235 |
| QKI | QKI, KH domain containing, RNA binding | -0.0224395 |
| RYK | receptor-like tyrosine kinase | -0.0224018 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0222367 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0221562 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0221239 |
| GOLGA4 | golgin A4 | -0.0215171 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0213136 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0211358 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0211088 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0210158 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0206221 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0205927 |
| FTL | ferritin, light polypeptide | -0.0204646 |
