| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nafamostat (mesylate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL4 | ribosomal protein L4 | 0.129494 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0587547 |
| RPS2 | ribosomal protein S2 | 0.0442181 |
| RPS18 | ribosomal protein S18 | 0.0425532 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0392244 |
| CAPRIN2 | caprin family member 2 | 0.0352676 |
| RBM25 | RNA binding motif protein 25 | 0.0321095 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0319172 |
| RBM39 | RNA binding motif protein 39 | 0.0295186 |
| RAD51B | RAD51 paralog B | 0.029133 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0289017 |
| DSCAM | Down syndrome cell adhesion molecule | 0.02846 |
| ATM | ATM serine/threonine kinase | 0.0278538 |
| HLA-A | major histocompatibility complex, class I, A | 0.0267578 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0262824 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0262362 |
| ZNF146 | zinc finger protein 146 | 0.0261758 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.026131 |
| DHFR | dihydrofolate reductase | 0.0257638 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0257203 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0256352 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0253833 |
| DST | dystonin | 0.0244618 |
| OGA | O-GlcNAcase | 0.0242786 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0237074 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0237065 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0231722 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | 0.0219851 |
| ASPH | aspartate beta-hydroxylase | 0.0219702 |
| ZNF432 | zinc finger protein 432 | 0.0219531 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0217085 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0215056 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.020923 |
| HM13 | histocompatibility (minor) 13 | 0.0205939 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0205727 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0203331 |
| SMYD3 | SET and MYND domain containing 3 | 0.0201243 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0200342 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0198079 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.019693 |
| MKI67 | marker of proliferation Ki-67 | 0.0195658 |
| ANK2 | ankyrin 2, neuronal | 0.0194755 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0194261 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0193781 |
| BPTF | bromodomain PHD finger transcription factor | 0.0192747 |
| FRMD4A | FERM domain containing 4A | 0.0191099 |
| CEP112 | centrosomal protein 112kDa | 0.019072 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0189086 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0189046 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0186644 |
| EXOC4 | exocyst complex component 4 | 0.0186494 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | 0.0186327 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0184244 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.018311 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0179448 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0179093 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.017698 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0175705 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.017565 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0175197 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0174758 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0173403 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0173365 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0173265 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0173018 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0172984 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0172491 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0170405 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0169922 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0169013 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0168967 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0168371 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0167587 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0165674 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0164812 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0164088 |
| CUL1 | cullin 1 | 0.0160655 |
| TRIM44 | tripartite motif containing 44 | 0.0159761 |
| TMEM41B | transmembrane protein 41B | 0.0159151 |
| RPS12 | ribosomal protein S12 | 0.0159007 |
| NLK | nemo-like kinase | 0.0158666 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0158303 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0157842 |
| ANLN | anillin, actin binding protein | 0.015694 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0156641 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0153623 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0151619 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0150519 |
| HDAC9 | histone deacetylase 9 | 0.0150008 |
| SSH2 | slingshot protein phosphatase 2 | 0.014916 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0148545 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0147921 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0147321 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0146882 |
| ZNF407 | zinc finger protein 407 | 0.0146349 |
| H1-4 | H1.4 linker histone, cluster member | 0.0144778 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.014471 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0143864 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.0143643 |
| WWOX | WW domain containing oxidoreductase | 0.0143401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | -0.156069 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.149731 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.14207 |
| MT2A | metallothionein 2A | -0.09733 |
| NAV3 | neuron navigator 3 | -0.0864526 |
| HMGA1 | high mobility group AT-hook 1 | -0.0799626 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0761381 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.07501 |
| FRMD6 | FERM domain containing 6 | -0.0739173 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0698533 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.068369 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0667268 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0632061 |
| TMSB10 | thymosin beta 10 | -0.0617538 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0566299 |
| AHNAK | AHNAK nucleoprotein | -0.0565545 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0562406 |
| RPL8 | ribosomal protein L8 | -0.0556148 |
| MCL1 | myeloid cell leukemia 1 | -0.0549931 |
| PGK1 | phosphoglycerate kinase 1 | -0.0529322 |
| NDRG1 | N-myc downstream regulated 1 | -0.0521526 |
| PKM | pyruvate kinase, muscle | -0.0515158 |
| POTEF | POTE ankyrin domain family, member F | -0.0515109 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0502769 |
| TPM4 | tropomyosin 4 | -0.0501632 |
| ACTG1 | actin gamma 1 | -0.0496106 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0494256 |
| ZNF438 | zinc finger protein 438 | -0.0467198 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0461197 |
| UPP1 | uridine phosphorylase 1 | -0.0456576 |
| LDHA | lactate dehydrogenase A | -0.0449637 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0449221 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0434479 |
| RPL7 | ribosomal protein L7 | -0.0429679 |
| UBC | ubiquitin C | -0.0427124 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0424949 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0418626 |
| ATP13A3 | ATPase type 13A3 | -0.041563 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0412507 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0409972 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0404307 |
| CORO1C | coronin, actin binding protein, 1C | -0.0402313 |
| RPL23 | ribosomal protein L23 | -0.0394266 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0388725 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0383813 |
| USP3 | ubiquitin specific peptidase 3 | -0.0382403 |
| GLRX | glutaredoxin (thioltransferase) | -0.0375556 |
| WAC | WW domain containing adaptor with coiled-coil | -0.03747 |
| RHOA | ras homolog family member A | -0.0374085 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0372364 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0372154 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0359197 |
| RASA2 | RAS p21 protein activator 2 | -0.0355497 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0355222 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0353228 |
| LAMB3 | laminin, beta 3 | -0.0351114 |
| CALD1 | caldesmon 1 | -0.0350565 |
| NUP58 | nucleoporin 58 | -0.0349863 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0349123 |
| FLNB | filamin B, beta | -0.0347157 |
| STC1 | stanniocalcin 1 | -0.0341602 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0341028 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0337111 |
| PFN1 | profilin 1 | -0.0330802 |
| RPS15 | ribosomal protein S15 | -0.0325401 |
| FMNL2 | formin-like 2 | -0.0319467 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0318929 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0318687 |
| SETD5 | SET domain containing 5 | -0.0313012 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0312327 |
| BRD4 | bromodomain containing 4 | -0.0309588 |
| DGKI | diacylglycerol kinase, iota | -0.0308691 |
| RPLP2 | ribosomal protein, large, P2 | -0.0304007 |
| RTN4 | reticulon 4 | -0.0302203 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0301594 |
| NABP1 | nucleic acid binding protein 1 | -0.0299312 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0294378 |
| RLF | rearranged L-myc fusion | -0.0292659 |
| TAOK1 | TAO kinase 1 | -0.029075 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0287385 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0283894 |
| FHL2 | four and a half LIM domains 2 | -0.0279843 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0278817 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0277735 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0276845 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0272191 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0271099 |
| PHIP | pleckstrin homology domain interacting protein | -0.0268717 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0265964 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0265302 |
| COG5 | component of oligomeric golgi complex 5 | -0.026426 |
| RPS21 | ribosomal protein S21 | -0.0264105 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0263262 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0262136 |
| FTL | ferritin, light polypeptide | -0.026136 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.025962 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0255192 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0254526 |
| RHEB | Ras homolog enriched in brain | -0.025245 |
| CANX | calnexin | -0.0245124 |
