| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EIF1 | eukaryotic translation initiation factor 1 | 0.0458732 |
| VIM | vimentin | 0.0393104 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0336742 |
| MT2A | metallothionein 2A | 0.0310904 |
| RPS6 | ribosomal protein S6 | 0.0291126 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0257287 |
| RPLP2 | ribosomal protein, large, P2 | 0.0246076 |
| RPS8 | ribosomal protein S8 | 0.0224993 |
| PRELID2 | PRELI domain containing 2 | 0.0220808 |
| RPL9 | ribosomal protein L9 | 0.0210827 |
| RPS23 | ribosomal protein S23 | 0.0203129 |
| RPS2 | ribosomal protein S2 | 0.0201603 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.019821 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0190976 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0188086 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0181107 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0178954 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0177466 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0176314 |
| RPL23 | ribosomal protein L23 | 0.0174384 |
| VMP1 | vacuole membrane protein 1 | 0.0168237 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0163799 |
| INSR | insulin receptor | 0.0157942 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0155027 |
| RPLP0 | ribosomal protein, large, P0 | 0.0153703 |
| RPL7A | ribosomal protein L7a | 0.0151379 |
| RPS24 | ribosomal protein S24 | 0.0151229 |
| NEK7 | NIMA-related kinase 7 | 0.0150598 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0147711 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0145091 |
| RPL36A | ribosomal protein L36a | 0.0141647 |
| OGA | O-GlcNAcase | 0.013993 |
| JMJD1C | jumonji domain containing 1C | 0.0134023 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0133196 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0130708 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0130667 |
| GOLGA4 | golgin A4 | 0.0130244 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0130087 |
| VCL | vinculin | 0.0129074 |
| FNIP1 | folliculin interacting protein 1 | 0.0128156 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.012643 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0125855 |
| RBM39 | RNA binding motif protein 39 | 0.0124489 |
| RPS13 | ribosomal protein S13 | 0.0123258 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.012308 |
| RPL26 | ribosomal protein L26 | 0.0122816 |
| RPS18 | ribosomal protein S18 | 0.0122445 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0118877 |
| RPS14 | ribosomal protein S14 | 0.0118518 |
| RPL12 | ribosomal protein L12 | 0.0118344 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0118181 |
| MYO9A | myosin IXA | 0.0117178 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0115889 |
| RPL35A | ribosomal protein L35a | 0.0113895 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0113193 |
| MICU1 | mitochondrial calcium uptake 1 | 0.011262 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0111978 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0111254 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0110136 |
| FLNB | filamin B, beta | 0.0109628 |
| SDC4 | syndecan 4 | 0.0108056 |
| RPL32 | ribosomal protein L32 | 0.0107562 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0106825 |
| SMYD3 | SET and MYND domain containing 3 | 0.010561 |
| EHBP1 | EH domain binding protein 1 | 0.0104372 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0104315 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0102811 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0101716 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0101372 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0101273 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0100753 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.00996216 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00989319 |
| MT1X | metallothionein 1X | 0.0098756 |
| TOX2 | TOX high mobility group box family member 2 | 0.00987536 |
| RPL4 | ribosomal protein L4 | 0.00981233 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.00978232 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.00975324 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.00975234 |
| RPL5 | ribosomal protein L5 | 0.00967999 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00960411 |
| CDK19 | cyclin-dependent kinase 19 | 0.00960253 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00958159 |
| MCL1 | myeloid cell leukemia 1 | 0.00955256 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.00945452 |
| RPL36 | ribosomal protein L36 | 0.00944756 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.00935067 |
| RBBP6 | retinoblastoma binding protein 6 | 0.00929176 |
| OTUD5 | OTU deubiquitinase 5 | 0.00928867 |
| TGM2 | transglutaminase 2 | 0.00925128 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00921994 |
| INTS6 | integrator complex subunit 6 | 0.00920887 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.00916297 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.00912581 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0091241 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.00906949 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.00903733 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00900087 |
| B2M | beta-2-microglobulin | 0.00896906 |
| AHR | aryl hydrocarbon receptor | 0.00896401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.116291 |
| FRMD4A | FERM domain containing 4A | -0.0841966 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0658522 |
| FN1 | fibronectin 1 | -0.0654686 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0549005 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0527371 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0447954 |
| PDE10A | phosphodiesterase 10A | -0.0405722 |
| PGK1 | phosphoglycerate kinase 1 | -0.0374876 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0343359 |
| NAV2 | neuron navigator 2 | -0.0338668 |
| SMAD3 | SMAD family member 3 | -0.0338241 |
| NDRG1 | N-myc downstream regulated 1 | -0.0329413 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0315393 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0301361 |
| SPAG9 | sperm associated antigen 9 | -0.0282694 |
| CD44 | CD44 molecule (Indian blood group) | -0.0263019 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0252442 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0246082 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0240445 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0238239 |
| LOXL2 | lysyl oxidase-like 2 | -0.0233918 |
| SQSTM1 | sequestosome 1 | -0.0231595 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0228812 |
| THBS2 | thrombospondin 2 | -0.0226047 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0224036 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0207327 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0200333 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0199604 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0191068 |
| SYNJ2 | synaptojanin 2 | -0.0185402 |
| ANXA2 | annexin A2 | -0.0185297 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0183436 |
| GLIS3 | GLIS family zinc finger 3 | -0.0181725 |
| COL1A2 | collagen, type I, alpha 2 | -0.0180052 |
| IER3 | immediate early response 3 | -0.0178174 |
| ATP13A3 | ATPase type 13A3 | -0.0176716 |
| TNS3 | tensin 3 | -0.0176025 |
| HLA-E | major histocompatibility complex, class I, E | -0.0175437 |
| CD164 | CD164 molecule, sialomucin | -0.0172706 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0169761 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.016953 |
| RAI1 | retinoic acid induced 1 | -0.0168888 |
| LDHA | lactate dehydrogenase A | -0.016747 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0162944 |
| APP | amyloid beta (A4) precursor protein | -0.0162302 |
| BICC1 | BicC family RNA binding protein 1 | -0.0161871 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0157347 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0157193 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0154564 |
| CENPF | centromere protein F, 350/400kDa | -0.015351 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0152556 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0152065 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0151685 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -0.0151425 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.015008 |
| DIAPH2 | diaphanous-related formin 2 | -0.0146221 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0143459 |
| NGLY1 | N-glycanase 1 | -0.0143236 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0142484 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0141948 |
| SFTPA2 | surfactant protein A2 | -0.0140839 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0139873 |
| VCAN | versican | -0.0139498 |
| CANX | calnexin | -0.0139083 |
| FLNA | filamin A, alpha | -0.0138744 |
| AFDN | afadin, adherens junction formation factor | -0.0137856 |
| TPM4 | tropomyosin 4 | -0.0136277 |
| THBS1 | thrombospondin 1 | -0.0135792 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0135569 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.013303 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0132577 |
| DENND5A | DENN/MADD domain containing 5A | -0.0131527 |
| RTN4 | reticulon 4 | -0.0129744 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0128937 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0128174 |
| MKI67 | marker of proliferation Ki-67 | -0.0126589 |
| CD2AP | CD2-associated protein | -0.0126309 |
| WDR45B | WD repeat domain 45B | -0.0125789 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0125708 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0125531 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0125506 |
| HLA-C | major histocompatibility complex, class I, C | -0.0125381 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0125237 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0124982 |
| CDH13 | cadherin 13 | -0.0124868 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0124331 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0124118 |
| QKI | QKI, KH domain containing, RNA binding | -0.0123716 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0123713 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0122213 |
| RNF213 | ring finger protein 213 | -0.0121356 |
| PFKP | phosphofructokinase, platelet | -0.0121322 |
| SNX9 | sorting nexin 9 | -0.0121068 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0120987 |
| ARFGEF3 | ARFGEF family member 3 | -0.0120562 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0120528 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0120241 |
| C3 | complement component 3 | -0.0120176 |
| MYOF | myoferlin | -0.0120168 |
