| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0858092 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0720018 |
| B2M | beta-2-microglobulin | 0.0713141 |
| CALR | calreticulin | 0.0698955 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0614517 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.060449 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0601449 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0599401 |
| PRELID2 | PRELI domain containing 2 | 0.0589407 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0581365 |
| GOLGA4 | golgin A4 | 0.0533025 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0527006 |
| EGR1 | early growth response 1 | 0.0525523 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0520197 |
| RPL12 | ribosomal protein L12 | 0.051381 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0492493 |
| JMJD1C | jumonji domain containing 1C | 0.0474259 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0473855 |
| MCL1 | myeloid cell leukemia 1 | 0.0465721 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0465666 |
| HLA-A | major histocompatibility complex, class I, A | 0.0463951 |
| MT2A | metallothionein 2A | 0.046051 |
| FTL | ferritin, light polypeptide | 0.0459598 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0458837 |
| PDE10A | phosphodiesterase 10A | 0.0458026 |
| RAD51B | RAD51 paralog B | 0.0446755 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0435688 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0434606 |
| MORF4L2 | mortality factor 4 like 2 | 0.0428819 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0424632 |
| RBM39 | RNA binding motif protein 39 | 0.0423486 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0415897 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0402066 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0397505 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0390664 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0389463 |
| RPS12 | ribosomal protein S12 | 0.0385752 |
| TMF1 | TATA element modulatory factor 1 | 0.0381118 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0375344 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0370023 |
| RPL4 | ribosomal protein L4 | 0.0366583 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0365798 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0365137 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0364652 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.0363737 |
| SMYD3 | SET and MYND domain containing 3 | 0.0362677 |
| CANX | calnexin | 0.0355267 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0351102 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.034943 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0349025 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0346359 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0331486 |
| SBF2 | SET binding factor 2 | 0.0328432 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0327663 |
| USP8 | ubiquitin specific peptidase 8 | 0.0320568 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0318886 |
| ADM | adrenomedullin | 0.0312626 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.031072 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0308682 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0305808 |
| MAGT1 | magnesium transporter 1 | 0.0304744 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0298283 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0295173 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.029501 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0294687 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0291878 |
| HELZ | helicase with zinc finger | 0.0289906 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0289649 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0285194 |
| RNF216 | ring finger protein 216 | 0.0284856 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0284538 |
| FAM13B | family with sequence similarity 13, member B | 0.0284261 |
| RPL28 | ribosomal protein L28 | 0.0283858 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0283097 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0282717 |
| MYO6 | myosin VI | 0.028238 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.027923 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0277515 |
| NGLY1 | N-glycanase 1 | 0.0274827 |
| NBAS | neuroblastoma amplified sequence | 0.027148 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0271088 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0270008 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0265117 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0264025 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0261767 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.026044 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0260168 |
| TPM2 | tropomyosin 2 (beta) | 0.0260141 |
| RACK1 | receptor for activated C kinase 1 | 0.0259374 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0259109 |
| CUL4B | cullin 4B | 0.0258396 |
| POM121 | POM121 transmembrane nucleoporin | 0.025822 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0258015 |
| FNIP1 | folliculin interacting protein 1 | 0.0256457 |
| RECQL | RecQ helicase-like | 0.025603 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0255705 |
| STK10 | serine/threonine kinase 10 | 0.0254867 |
| RAI1 | retinoic acid induced 1 | 0.0253645 |
| VEGFA | vascular endothelial growth factor A | 0.025313 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0250015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.227108 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190162 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.147425 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.109391 |
| NDRG1 | N-myc downstream regulated 1 | -0.0914576 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0794788 |
| AHNAK | AHNAK nucleoprotein | -0.0784975 |
| ANXA2 | annexin A2 | -0.0767903 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0767627 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0648349 |
| GLIS3 | GLIS family zinc finger 3 | -0.063355 |
| LOXL2 | lysyl oxidase-like 2 | -0.0619991 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0606896 |
| HMGA2 | high mobility group AT-hook 2 | -0.0601038 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0577844 |
| RAB1A | RAB1A, member RAS oncogene family | -0.056882 |
| PRSS23 | protease, serine, 23 | -0.0549068 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.054472 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0543251 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0540672 |
| SRPK2 | SRSF protein kinase 2 | -0.0536806 |
| WTAP | Wilms tumor 1 associated protein | -0.0535312 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0534738 |
| RTN4 | reticulon 4 | -0.0526671 |
| CADM1 | cell adhesion molecule 1 | -0.0523617 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0516896 |
| MEF2A | myocyte enhancer factor 2A | -0.0506146 |
| AOPEP | aminopeptidase O (putative) | -0.0500243 |
| MT1X | metallothionein 1X | -0.0498797 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0490649 |
| RNF24 | ring finger protein 24 | -0.0486339 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0483462 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0483075 |
| SMAD3 | SMAD family member 3 | -0.048004 |
| PGK1 | phosphoglycerate kinase 1 | -0.0464657 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0463369 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0460755 |
| CDH13 | cadherin 13 | -0.0459988 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0456196 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0451369 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0440444 |
| LOX | lysyl oxidase | -0.0439862 |
| MAP1B | microtubule-associated protein 1B | -0.0434275 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0428504 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0424185 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0421136 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0417176 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0416595 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0406794 |
| TMSB10 | thymosin beta 10 | -0.0403373 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0399739 |
| CUL3 | cullin 3 | -0.0398975 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0394509 |
| CLTC | clathrin, heavy chain (Hc) | -0.0393954 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0392882 |
| PTK2 | protein tyrosine kinase 2 | -0.0380182 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0379312 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0376078 |
| RAB10 | RAB10, member RAS oncogene family | -0.0375594 |
| OGA | O-GlcNAcase | -0.0368891 |
| NRP1 | neuropilin 1 | -0.0365403 |
| ZNF644 | zinc finger protein 644 | -0.0363352 |
| USP34 | ubiquitin specific peptidase 34 | -0.0352822 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0346811 |
| ERBIN | erbb2 interacting protein | -0.0337023 |
| TNNC1 | troponin C type 1 (slow) | -0.0336859 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0336323 |
| TAGLN2 | transgelin 2 | -0.0335369 |
| ZNF292 | zinc finger protein 292 | -0.0334351 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0333365 |
| OSMR | oncostatin M receptor | -0.0332297 |
| AHR | aryl hydrocarbon receptor | -0.0331178 |
| NRXN3 | neurexin 3 | -0.0330782 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0330021 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0324568 |
| CDK6 | cyclin-dependent kinase 6 | -0.0320992 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0319461 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0318449 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0316443 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0312911 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0310284 |
| H3-3B | H3.3 histone B | -0.0308441 |
| CALD1 | caldesmon 1 | -0.0307157 |
| ACTN4 | actinin, alpha 4 | -0.0303779 |
| COL5A1 | collagen, type V, alpha 1 | -0.0302779 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0302102 |
| APP | amyloid beta (A4) precursor protein | -0.0301675 |
| RASAL2 | RAS protein activator like 2 | -0.0299395 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0297962 |
| ANKRD28 | ankyrin repeat domain 28 | -0.029567 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | -0.0292703 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0291371 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0290347 |
| VCL | vinculin | -0.0289945 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.028978 |
| SUCO | SUN domain containing ossification factor | -0.0289276 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0287198 |
| NKTR | natural killer cell triggering receptor | -0.0287193 |
| SFTPA2 | surfactant protein A2 | -0.028635 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0283431 |
