| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nafamostat (mesylate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.124083 |
| RBM39 | RNA binding motif protein 39 | 0.11664 |
| RPL4 | ribosomal protein L4 | 0.0963977 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0728965 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0629692 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0628341 |
| GOLGA4 | golgin A4 | 0.0587898 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0574881 |
| RPS12 | ribosomal protein S12 | 0.0529193 |
| CAPRIN2 | caprin family member 2 | 0.051011 |
| EGR1 | early growth response 1 | 0.049122 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0474042 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0453939 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0434946 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0421703 |
| OGA | O-GlcNAcase | 0.0411383 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0410063 |
| PER1 | period circadian clock 1 | 0.0404381 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0401084 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0400219 |
| SMYD3 | SET and MYND domain containing 3 | 0.0399949 |
| CALR | calreticulin | 0.0399153 |
| JMJD1C | jumonji domain containing 1C | 0.0388771 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0384768 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0379547 |
| ZNF292 | zinc finger protein 292 | 0.0378779 |
| HDAC9 | histone deacetylase 9 | 0.0375401 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0375059 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0372671 |
| RPS6 | ribosomal protein S6 | 0.0371547 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0360416 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0360317 |
| YBX3 | Y box binding protein 3 | 0.0355911 |
| RAB6A | RAB6A, member RAS oncogene family | 0.035237 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0349748 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0348978 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0340834 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.033475 |
| RBM25 | RNA binding motif protein 25 | 0.0334445 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0326145 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0324876 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0323895 |
| TPR | translocated promoter region, nuclear basket protein | 0.032361 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0320925 |
| RPL32 | ribosomal protein L32 | 0.0314488 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0313856 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.031373 |
| YAP1 | Yes-associated protein 1 | 0.0313108 |
| NBAS | neuroblastoma amplified sequence | 0.0312196 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0309393 |
| RPL26 | ribosomal protein L26 | 0.0309381 |
| KIF20B | kinesin family member 20B | 0.0306288 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0304349 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0302724 |
| RPL12 | ribosomal protein L12 | 0.0301633 |
| RPL5 | ribosomal protein L5 | 0.0300896 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0300419 |
| EZR | ezrin | 0.0297041 |
| EFNA5 | ephrin-A5 | 0.0293455 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291551 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0291046 |
| CYTH1 | cytohesin 1 | 0.0282935 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.0282386 |
| HLA-A | major histocompatibility complex, class I, A | 0.0282343 |
| RPS2 | ribosomal protein S2 | 0.027522 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0274906 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.026953 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.0269039 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.026822 |
| FTL | ferritin, light polypeptide | 0.0267279 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0266745 |
| MATR3 | matrin 3 | 0.0266055 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.0265508 |
| RPL36 | ribosomal protein L36 | 0.0265216 |
| DIDO1 | death inducer-obliterator 1 | 0.0263863 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0263502 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0263315 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0262399 |
| MED13 | mediator complex subunit 13 | 0.0262113 |
| CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | 0.0261679 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0258713 |
| NOP58 | NOP58 ribonucleoprotein | 0.0258623 |
| BRD4 | bromodomain containing 4 | 0.0257756 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0257183 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0256399 |
| MORF4L2 | mortality factor 4 like 2 | 0.0256019 |
| RPL37A | ribosomal protein L37a | 0.0255561 |
| RRBP1 | ribosome binding protein 1 | 0.0253371 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | 0.0252318 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0250936 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0249831 |
| SRPK2 | SRSF protein kinase 2 | 0.0247737 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0246659 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0244707 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0244139 |
| UBAC2 | UBA domain containing 2 | 0.0243793 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0240195 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0239276 |
| RPL13A | ribosomal protein L13a | 0.023865 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0238536 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.391317 |
| CD44 | CD44 molecule (Indian blood group) | -0.130384 |
| POTEF | POTE ankyrin domain family, member F | -0.0863194 |
| LDHA | lactate dehydrogenase A | -0.0818826 |
| HMGA2 | high mobility group AT-hook 2 | -0.0666123 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0633751 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0624249 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0516115 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0507312 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0500006 |
| PKM | pyruvate kinase, muscle | -0.0488845 |
| TMSB10 | thymosin beta 10 | -0.0483045 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0465513 |
| AHNAK | AHNAK nucleoprotein | -0.0460786 |
| RAI14 | retinoic acid induced 14 | -0.0460351 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0451561 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0430373 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0427055 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0417602 |
| ANXA2 | annexin A2 | -0.0417447 |
| FLNB | filamin B, beta | -0.0416586 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0400907 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0395054 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0392965 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0390836 |
| PRKCA | protein kinase C, alpha | -0.0388601 |
| PRSS23 | protease, serine, 23 | -0.0385424 |
| OXSR1 | oxidative stress responsive 1 | -0.0382399 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0382011 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.036868 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0348271 |
| PODXL | podocalyxin-like | -0.0343894 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0341642 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.034156 |
| ZNF609 | zinc finger protein 609 | -0.0334054 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0332359 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0332156 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0324478 |
| RAD51B | RAD51 paralog B | -0.0323793 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.03221 |
| NAV3 | neuron navigator 3 | -0.0321183 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0319363 |
| NLK | nemo-like kinase | -0.0318381 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0314966 |
| PCED1B | PC-esterase domain containing 1B | -0.0314608 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0312437 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0307827 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0299345 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0295861 |
| ABR | active BCR-related | -0.0293526 |
| ATP13A3 | ATPase type 13A3 | -0.029269 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0291215 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0289474 |
| H3-3B | H3.3 histone B | -0.0287978 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0283798 |
| VCL | vinculin | -0.0282256 |
| TAOK1 | TAO kinase 1 | -0.0280369 |
| TPM4 | tropomyosin 4 | -0.027921 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0276539 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0274971 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0273272 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0269929 |
| RIN2 | Ras and Rab interactor 2 | -0.0264997 |
| CALU | calumenin | -0.0263502 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0263388 |
| NGLY1 | N-glycanase 1 | -0.0263315 |
| SVIL | supervillin | -0.0263225 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0259661 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0258332 |
| COL5A1 | collagen, type V, alpha 1 | -0.0257479 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0256726 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0256027 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0254745 |
| PRR16 | proline rich 16 | -0.0254487 |
| MSN | moesin | -0.0253598 |
| NAV2 | neuron navigator 2 | -0.0252927 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0252345 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0252344 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0241053 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0240827 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0238215 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0237397 |
| GPC5 | glypican 5 | -0.0237125 |
| MAP1B | microtubule-associated protein 1B | -0.0235877 |
| SKIL | SKI-like proto-oncogene | -0.0234568 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.023419 |
| PYGL | phosphorylase, glycogen, liver | -0.0234071 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0232959 |
| CDCP1 | CUB domain containing protein 1 | -0.0231798 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0231321 |
| PDE8A | phosphodiesterase 8A | -0.0230584 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0228852 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0228377 |
| NF1 | neurofibromin 1 | -0.0228332 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0226884 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0226506 |
| SIN3A | SIN3 transcription regulator family member A | -0.0224019 |
| GPC6 | glypican 6 | -0.0220691 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0219791 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0217694 |
