| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RBM39 | RNA binding motif protein 39 | 0.0998791 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0918004 |
| RPL4 | ribosomal protein L4 | 0.0689902 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0679852 |
| EZR | ezrin | 0.055539 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0547521 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0506802 |
| OGA | O-GlcNAcase | 0.0473585 |
| RPS3 | ribosomal protein S3 | 0.0460426 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0429295 |
| RPS2 | ribosomal protein S2 | 0.0403734 |
| RPS12 | ribosomal protein S12 | 0.0395647 |
| RPL18 | ribosomal protein L18 | 0.0378358 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0345761 |
| RBM25 | RNA binding motif protein 25 | 0.0331007 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0311992 |
| RPL37A | ribosomal protein L37a | 0.0294329 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0292969 |
| ATF4 | activating transcription factor 4 | 0.028361 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0276008 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0275505 |
| RPL5 | ribosomal protein L5 | 0.0274123 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0271463 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0262163 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0261217 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0258049 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0257139 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025599 |
| DHFR | dihydrofolate reductase | 0.0244529 |
| JUP | junction plakoglobin | 0.0236811 |
| TMEM41B | transmembrane protein 41B | 0.0235971 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0235945 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0234947 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0232966 |
| RPL13A | ribosomal protein L13a | 0.0231559 |
| RPL26 | ribosomal protein L26 | 0.0230137 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0229678 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0228449 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0228331 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0227389 |
| RPS18 | ribosomal protein S18 | 0.0227183 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.022498 |
| HMGB2 | high mobility group box 2 | 0.0223092 |
| SET | SET nuclear proto-oncogene | 0.0222385 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0222289 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0220115 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0220052 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0217941 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0216813 |
| THOC2 | THO complex 2 | 0.0212831 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0205789 |
| RPS15A | ribosomal protein S15a | 0.020127 |
| LAMB3 | laminin, beta 3 | 0.0196286 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0196255 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0196241 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.01957 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0194899 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0194479 |
| SLK | STE20-like kinase | 0.0192779 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.019268 |
| PNN | pinin, desmosome associated protein | 0.0192005 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0191999 |
| ITSN2 | intersectin 2 | 0.0190204 |
| STC2 | stanniocalcin 2 | 0.0190144 |
| MUC13 | mucin 13, cell surface associated | 0.0187987 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0187171 |
| VIM | vimentin | 0.0184698 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0183356 |
| PRPF6 | pre-mRNA processing factor 6 | 0.0180945 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0179882 |
| JUN | jun proto-oncogene | 0.0173653 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.0173402 |
| PRELID2 | PRELI domain containing 2 | 0.0171704 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.0171488 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0171268 |
| ZFHX3 | zinc finger homeobox 3 | 0.0169298 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0165704 |
| MKI67 | marker of proliferation Ki-67 | 0.0164731 |
| PLEC | plectin | 0.0164555 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0163453 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0161741 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0160738 |
| EGR1 | early growth response 1 | 0.016057 |
| DST | dystonin | 0.0160177 |
| SMYD3 | SET and MYND domain containing 3 | 0.0159073 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0157188 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0156766 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0156347 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0155929 |
| RPL9 | ribosomal protein L9 | 0.015356 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0151989 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0149327 |
| BRD2 | bromodomain containing 2 | 0.0147543 |
| RANBP1 | RAN binding protein 1 | 0.0146718 |
| TMF1 | TATA element modulatory factor 1 | 0.0146634 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0144984 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0144222 |
| BCL2L1 | BCL2-like 1 | 0.0144134 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.0142562 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.0142245 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.305614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.170703 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.127146 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.107616 |
| KRT8 | keratin 8, type II | -0.0981078 |
| TMEM123 | transmembrane protein 123 | -0.0934726 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0881842 |
| KRT18 | keratin 18, type I | -0.0858656 |
| ANXA2 | annexin A2 | -0.0748223 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0675885 |
| LDHA | lactate dehydrogenase A | -0.0652345 |
| RHEB | Ras homolog enriched in brain | -0.0651824 |
| AHNAK | AHNAK nucleoprotein | -0.0643706 |
| UBC | ubiquitin C | -0.0625033 |
| NDRG1 | N-myc downstream regulated 1 | -0.0602637 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0587047 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0584974 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0575569 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0572046 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0571974 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.057016 |
| PERP | PERP, TP53 apoptosis effector | -0.0558865 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0546189 |
| ZNRF3 | zinc and ring finger 3 | -0.0534428 |
| FNDC3B | fibronectin type III domain containing 3B | -0.051664 |
| PGK1 | phosphoglycerate kinase 1 | -0.051498 |
| FAT1 | FAT atypical cadherin 1 | -0.051328 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0511475 |
| CANX | calnexin | -0.0493524 |
| POTEF | POTE ankyrin domain family, member F | -0.0485747 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0477454 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0473701 |
| ACTG1 | actin gamma 1 | -0.0473545 |
| S100A10 | S100 calcium binding protein A10 | -0.0465051 |
| RPL8 | ribosomal protein L8 | -0.0461216 |
| PKM | pyruvate kinase, muscle | -0.0452216 |
| RPLP0 | ribosomal protein, large, P0 | -0.0447086 |
| RPS21 | ribosomal protein S21 | -0.0434821 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0433338 |
| HMGA1 | high mobility group AT-hook 1 | -0.0430614 |
| CTSD | cathepsin D | -0.0421569 |
| CST3 | cystatin C | -0.0413413 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0412687 |
| MED13L | mediator complex subunit 13-like | -0.0412117 |
| SETD5 | SET domain containing 5 | -0.0409774 |
| TMSB10 | thymosin beta 10 | -0.0406083 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0405815 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0401383 |
| GNAS | GNAS complex locus | -0.0397483 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0393451 |
| RPL28 | ribosomal protein L28 | -0.0393225 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0389022 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0374304 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.036659 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0364041 |
| YAP1 | Yes-associated protein 1 | -0.0354834 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0345484 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0344133 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0341531 |
| TPM4 | tropomyosin 4 | -0.0335421 |
| SNX9 | sorting nexin 9 | -0.0334367 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0333157 |
| RPS11 | ribosomal protein S11 | -0.0329104 |
| EPCAM | epithelial cell adhesion molecule | -0.0327107 |
| MSI2 | musashi RNA-binding protein 2 | -0.0323601 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0322495 |
| MYO1E | myosin IE | -0.0321602 |
| FTL | ferritin, light polypeptide | -0.0321436 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0321089 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0319023 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0318537 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.031717 |
| ACTN4 | actinin, alpha 4 | -0.03158 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0314929 |
| RHOA | ras homolog family member A | -0.0312186 |
| SERINC5 | serine incorporator 5 | -0.0310942 |
| SLTM | SAFB-like, transcription modulator | -0.0310505 |
| DEK | DEK proto-oncogene | -0.0310088 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0305538 |
| RPL15 | ribosomal protein L15 | -0.0305476 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0304409 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.030411 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0303892 |
| RPS25 | ribosomal protein S25 | -0.0301559 |
| FBXO11 | F-box protein 11 | -0.0300861 |
| SRPK2 | SRSF protein kinase 2 | -0.0299649 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0293205 |
| DSG2 | desmoglein 2 | -0.0292578 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0290155 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0288834 |
| RYBP | RING1 and YY1 binding protein | -0.0288483 |
| RPL19 | ribosomal protein L19 | -0.028843 |
| RPS15 | ribosomal protein S15 | -0.0288266 |
| FAM3C | family with sequence similarity 3, member C | -0.028778 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0286457 |
| IER3 | immediate early response 3 | -0.0286383 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0285907 |
| RPL7A | ribosomal protein L7a | -0.0284374 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 | -0.0281849 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0280358 |
