| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.102808 |
| RPL4 | ribosomal protein L4 | 0.0856603 |
| LAMA4 | laminin, alpha 4 | 0.0837685 |
| EGR1 | early growth response 1 | 0.0750204 |
| FHIT | fragile histidine triad | 0.0689644 |
| RPS6 | ribosomal protein S6 | 0.0662036 |
| RAD51B | RAD51 paralog B | 0.0631003 |
| VCL | vinculin | 0.0577284 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0570643 |
| RBM25 | RNA binding motif protein 25 | 0.0544974 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.05401 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0523139 |
| RPS2 | ribosomal protein S2 | 0.0504986 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0481404 |
| DSPP | dentin sialophosphoprotein | 0.0449462 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.044495 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.043512 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0424126 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0419055 |
| HLA-A | major histocompatibility complex, class I, A | 0.0392322 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0391399 |
| SEPTIN9 | septin 9 | 0.0384581 |
| EHBP1 | EH domain binding protein 1 | 0.0368547 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0364855 |
| RPS12 | ribosomal protein S12 | 0.0362999 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0361748 |
| SMYD3 | SET and MYND domain containing 3 | 0.0351397 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0349743 |
| LMO7 | LIM domain 7 | 0.0342617 |
| HM13 | histocompatibility (minor) 13 | 0.03184 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0313359 |
| CD9 | CD9 molecule | 0.0311977 |
| RPL26 | ribosomal protein L26 | 0.0306808 |
| EGFR | epidermal growth factor receptor | 0.0306793 |
| JMJD1C | jumonji domain containing 1C | 0.0304874 |
| RPS8 | ribosomal protein S8 | 0.0301624 |
| RPLP1 | ribosomal protein, large, P1 | 0.0297436 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0295894 |
| CCND1 | cyclin D1 | 0.0295772 |
| RPS14 | ribosomal protein S14 | 0.0293672 |
| PTMA | prothymosin, alpha | 0.029294 |
| CUX1 | cut-like homeobox 1 | 0.0292017 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0291504 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0282598 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0282135 |
| RPL18 | ribosomal protein L18 | 0.0279472 |
| ANXA3 | annexin A3 | 0.0272834 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0272441 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0268447 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0268113 |
| MTAP | methylthioadenosine phosphorylase | 0.026594 |
| RPL35A | ribosomal protein L35a | 0.0264651 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0256225 |
| KLK10 | kallikrein-related peptidase 10 | 0.0255906 |
| S100A6 | S100 calcium binding protein A6 | 0.0253827 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0249967 |
| RCOR1 | REST corepressor 1 | 0.0246415 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0244558 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0238338 |
| SERINC5 | serine incorporator 5 | 0.0235385 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0233814 |
| VMP1 | vacuole membrane protein 1 | 0.0233522 |
| RPL31 | ribosomal protein L31 | 0.023323 |
| RPL13A | ribosomal protein L13a | 0.0233185 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0233073 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0232608 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0232593 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0230287 |
| RPL9 | ribosomal protein L9 | 0.0228075 |
| RPLP0 | ribosomal protein, large, P0 | 0.0227417 |
| SCFD1 | sec1 family domain containing 1 | 0.0227247 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0224302 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0222461 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.022214 |
| SGMS2 | sphingomyelin synthase 2 | 0.0221586 |
| CUL5 | cullin 5 | 0.0217564 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0216352 |
| GPC5 | glypican 5 | 0.0213678 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0212708 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0211856 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0209354 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0209276 |
| KRT18 | keratin 18, type I | 0.0207087 |
| RPS3 | ribosomal protein S3 | 0.0206999 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0206538 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0205169 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0203369 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0202022 |
| PHF3 | PHD finger protein 3 | 0.0201983 |
| DENND5B | DENN/MADD domain containing 5B | 0.0201385 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0200783 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.020068 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0200118 |
| WWC1 | WW and C2 domain containing 1 | 0.0199351 |
| RPL12 | ribosomal protein L12 | 0.0197177 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0197104 |
| EMP1 | epithelial membrane protein 1 | 0.0196545 |
| DST | dystonin | 0.0194486 |
| DUSP4 | dual specificity phosphatase 4 | 0.0193094 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0192897 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.124863 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.112377 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0796193 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0727039 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0687861 |
| NDRG1 | N-myc downstream regulated 1 | -0.0638637 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0548192 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0540162 |
| AHNAK | AHNAK nucleoprotein | -0.0534898 |
| UBC | ubiquitin C | -0.0493656 |
| TXNRD1 | thioredoxin reductase 1 | -0.0489878 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0471968 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0459929 |
| GOLGA4 | golgin A4 | -0.0452206 |
| TOP1 | topoisomerase (DNA) I | -0.0446715 |
| MED13L | mediator complex subunit 13-like | -0.0443584 |
| ZNF292 | zinc finger protein 292 | -0.0423728 |
| PKM | pyruvate kinase, muscle | -0.0421603 |
| COG5 | component of oligomeric golgi complex 5 | -0.0406971 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0396848 |
| USP3 | ubiquitin specific peptidase 3 | -0.0394139 |
| PFKP | phosphofructokinase, platelet | -0.0379596 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0375545 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0369458 |
| BBX | bobby sox homolog (Drosophila) | -0.0354936 |
| SDC4 | syndecan 4 | -0.0343947 |
| HMGA1 | high mobility group AT-hook 1 | -0.0342994 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0332629 |
| ATXN1 | ataxin 1 | -0.0330731 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0330025 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0324487 |
| DIAPH1 | diaphanous-related formin 1 | -0.0323869 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0320748 |
| ANXA2 | annexin A2 | -0.0320374 |
| LDHA | lactate dehydrogenase A | -0.0320196 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0318373 |
| EZR | ezrin | -0.0318337 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0316816 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0315205 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.031344 |
| IER3 | immediate early response 3 | -0.030952 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0306737 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0301782 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0298497 |
| TFRC | transferrin receptor | -0.0295358 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0295312 |
| RNF43 | ring finger protein 43 | -0.0294591 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0293034 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0293011 |
| ATP11B | ATPase, class VI, type 11B | -0.0284406 |
| SBF2 | SET binding factor 2 | -0.0271733 |
| NUP58 | nucleoporin 58 | -0.027071 |
| TES | testin LIM domain protein | -0.0269477 |
| MYO5B | myosin VB | -0.026877 |
| PARD3 | par-3 family cell polarity regulator | -0.026797 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0267228 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0263147 |
| ZNRF3 | zinc and ring finger 3 | -0.0263139 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0258477 |
| FOXO1 | forkhead box O1 | -0.025729 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0256249 |
| GLG1 | golgi glycoprotein 1 | -0.0255559 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0250521 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0244833 |
| RLF | rearranged L-myc fusion | -0.0244326 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0243959 |
| RNF145 | ring finger protein 145 | -0.0243568 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0241958 |
| EREG | epiregulin | -0.0239645 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0238901 |
| SLMAP | sarcolemma associated protein | -0.023847 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0238231 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0236794 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0235413 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0234456 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.023342 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0232595 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0232586 |
| SRPK1 | SRSF protein kinase 1 | -0.0232155 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0231029 |
| CALU | calumenin | -0.023042 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0230345 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0227376 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0227375 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0227298 |
| ARRDC3 | arrestin domain containing 3 | -0.0226093 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0221373 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0219812 |
| NAV2 | neuron navigator 2 | -0.021937 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0218094 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0217158 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0216174 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0215106 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0214657 |
| RPL3 | ribosomal protein L3 | -0.0213368 |
| ENO1 | enolase 1, (alpha) | -0.0212716 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0211695 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.021163 |
| YAP1 | Yes-associated protein 1 | -0.0211504 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0210458 |
