| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.149015 |
| RPL4 | ribosomal protein L4 | 0.14069 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0860062 |
| RBM39 | RNA binding motif protein 39 | 0.0854764 |
| RPS12 | ribosomal protein S12 | 0.0784675 |
| RPS2 | ribosomal protein S2 | 0.0768215 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0762392 |
| RPS3 | ribosomal protein S3 | 0.0735331 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0722754 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0718045 |
| DSPP | dentin sialophosphoprotein | 0.0718019 |
| PCBP2 | poly(rC) binding protein 2 | 0.0654485 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0633136 |
| ENO1 | enolase 1, (alpha) | 0.0628666 |
| SET | SET nuclear proto-oncogene | 0.0624443 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0624287 |
| RBM25 | RNA binding motif protein 25 | 0.0623643 |
| PRRC2C | proline-rich coiled-coil 2C | 0.061318 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0571093 |
| EGR1 | early growth response 1 | 0.0570588 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0547074 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0519858 |
| GOLGA4 | golgin A4 | 0.0503221 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0496423 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0493969 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.046606 |
| VMP1 | vacuole membrane protein 1 | 0.0462871 |
| OGA | O-GlcNAcase | 0.046137 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0452932 |
| PCM1 | pericentriolar material 1 | 0.0446236 |
| RPS18 | ribosomal protein S18 | 0.043478 |
| EZR | ezrin | 0.0410681 |
| RPL5 | ribosomal protein L5 | 0.0405183 |
| PNN | pinin, desmosome associated protein | 0.0400034 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0397363 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0396652 |
| RPL26 | ribosomal protein L26 | 0.0388038 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0383924 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0381473 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0374071 |
| JUN | jun proto-oncogene | 0.0364812 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0362194 |
| RPL18 | ribosomal protein L18 | 0.0357358 |
| RPL37A | ribosomal protein L37a | 0.0355164 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0347923 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0345602 |
| TMF1 | TATA element modulatory factor 1 | 0.034204 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0330914 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0329639 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0320324 |
| TPM3 | tropomyosin 3 | 0.0316986 |
| TLN1 | talin 1 | 0.0316983 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0311021 |
| YAP1 | Yes-associated protein 1 | 0.0305417 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0305323 |
| RAD51B | RAD51 paralog B | 0.0304105 |
| ZNF148 | zinc finger protein 148 | 0.0300369 |
| KIZ | kizuna centrosomal protein | 0.0298476 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0297462 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0294335 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0293423 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0289951 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0287476 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0286708 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0284984 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0276003 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0274793 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0274631 |
| ATF4 | activating transcription factor 4 | 0.0274545 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0273844 |
| RPS17 | ribosomal protein S17 | 0.0273092 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0270775 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0269496 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0269396 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0267688 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.026758 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0265932 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0264602 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0261221 |
| PRELID2 | PRELI domain containing 2 | 0.026111 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0258431 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0257805 |
| UBXN4 | UBX domain protein 4 | 0.0252498 |
| DST | dystonin | 0.0252088 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0251457 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.025042 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.024982 |
| RPS6 | ribosomal protein S6 | 0.0248764 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0246689 |
| RPS15A | ribosomal protein S15a | 0.024555 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.024334 |
| RPL3 | ribosomal protein L3 | 0.0242624 |
| BCL2L1 | BCL2-like 1 | 0.024008 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0238396 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0237333 |
| DHFR | dihydrofolate reductase | 0.0237026 |
| NONO | non-POU domain containing, octamer-binding | 0.0236864 |
| MKI67 | marker of proliferation Ki-67 | 0.0236109 |
| TOP1 | topoisomerase (DNA) I | 0.0236089 |
| ZNF292 | zinc finger protein 292 | 0.0234463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.375462 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.205954 |
| ACTG1 | actin gamma 1 | -0.0955696 |
| RPS24 | ribosomal protein S24 | -0.0863098 |
| ANXA2 | annexin A2 | -0.0837469 |
| HMGA1 | high mobility group AT-hook 1 | -0.0654797 |
| KRT18 | keratin 18, type I | -0.0614858 |
| RPLP0 | ribosomal protein, large, P0 | -0.0588867 |
| S100A10 | S100 calcium binding protein A10 | -0.0581636 |
| KRT8 | keratin 8, type II | -0.0576543 |
| AHNAK | AHNAK nucleoprotein | -0.05694 |
| RPS21 | ribosomal protein S21 | -0.0557635 |
| RPL35A | ribosomal protein L35a | -0.0546131 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0534969 |
| RPL38 | ribosomal protein L38 | -0.0504383 |
| RPS25 | ribosomal protein S25 | -0.0500881 |
| RPL27A | ribosomal protein L27a | -0.0496528 |
| FRMD5 | FERM domain containing 5 | -0.0494551 |
| GLG1 | golgi glycoprotein 1 | -0.0489045 |
| CDK6 | cyclin-dependent kinase 6 | -0.0479906 |
| ACTN4 | actinin, alpha 4 | -0.0474562 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0465314 |
| RPLP1 | ribosomal protein, large, P1 | -0.0462042 |
| VCL | vinculin | -0.0453573 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0448439 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0443883 |
| RPS23 | ribosomal protein S23 | -0.0442635 |
| CDH13 | cadherin 13 | -0.0439714 |
| CCND1 | cyclin D1 | -0.0434858 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0433781 |
| TMSB10 | thymosin beta 10 | -0.0432837 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0431914 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0430129 |
| LDHA | lactate dehydrogenase A | -0.0430033 |
| RPL8 | ribosomal protein L8 | -0.0425496 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0425455 |
| RPL36A | ribosomal protein L36a | -0.0419822 |
| H3-3B | H3.3 histone B | -0.0410751 |
| VDAC1 | voltage-dependent anion channel 1 | -0.040745 |
| MED13 | mediator complex subunit 13 | -0.0406278 |
| RPS13 | ribosomal protein S13 | -0.0404157 |
| INTS6 | integrator complex subunit 6 | -0.0390411 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0390061 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0381794 |
| RPL7A | ribosomal protein L7a | -0.0369322 |
| RPS15 | ribosomal protein S15 | -0.0369241 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0368746 |
| RPL19 | ribosomal protein L19 | -0.0357205 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0357145 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0354168 |
| TFRC | transferrin receptor | -0.0351683 |
| ITGA6 | integrin, alpha 6 | -0.0347007 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0346583 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0345375 |
| TPM4 | tropomyosin 4 | -0.0343579 |
| DEK | DEK proto-oncogene | -0.0339487 |
| RBMX | RNA binding motif protein, X-linked | -0.033831 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0336051 |
| IER3 | immediate early response 3 | -0.0333974 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0327839 |
| WASF2 | WAS protein family, member 2 | -0.0325848 |
| RPL32 | ribosomal protein L32 | -0.0324184 |
| PGK1 | phosphoglycerate kinase 1 | -0.0315184 |
| RPS11 | ribosomal protein S11 | -0.0311177 |
| POTEF | POTE ankyrin domain family, member F | -0.0308905 |
| ARF1 | ADP-ribosylation factor 1 | -0.0304629 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0300735 |
| H1-0 | H1.0 linker histone | -0.0297305 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0297137 |
| RPS10 | ribosomal protein S10 | -0.0296907 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0290578 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.02893 |
| MORF4L2 | mortality factor 4 like 2 | -0.0284119 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0282692 |
| TUBA1B | tubulin, alpha 1b | -0.0281755 |
| PTMA | prothymosin, alpha | -0.0280118 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0274856 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.027396 |
| PERP | PERP, TP53 apoptosis effector | -0.0268987 |
| COBL | cordon-bleu WH2 repeat protein | -0.0268588 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0268583 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0267615 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0267247 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.026611 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0264981 |
| ASTN2 | astrotactin 2 | -0.0260528 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0256893 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0256447 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.025523 |
| ATXN1 | ataxin 1 | -0.0253594 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0252618 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0250919 |
| RLIM | ring finger protein, LIM domain interacting | -0.024994 |
| RLF | rearranged L-myc fusion | -0.0249108 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0248591 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0247912 |
| SYT1 | synaptotagmin I | -0.0247898 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0245895 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0245764 |
| TUBB | tubulin, beta class I | -0.0245555 |
