| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nafamostat (mesylate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nafamostat (mesylate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.109902 |
| INHBA | inhibin, beta A | 0.103211 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0914548 |
| RPL4 | ribosomal protein L4 | 0.0739375 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0683983 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0643148 |
| HMGA2 | high mobility group AT-hook 2 | 0.0627812 |
| ASPH | aspartate beta-hydroxylase | 0.0551076 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0541674 |
| PTMA | prothymosin, alpha | 0.0514331 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0458918 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0446412 |
| RPS3 | ribosomal protein S3 | 0.0416173 |
| HLA-A | major histocompatibility complex, class I, A | 0.0370541 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370339 |
| RPS6 | ribosomal protein S6 | 0.0359825 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0345945 |
| RPS2 | ribosomal protein S2 | 0.0342795 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0334317 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0314297 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0310759 |
| RBM39 | RNA binding motif protein 39 | 0.0300837 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0291326 |
| RPS12 | ribosomal protein S12 | 0.0288243 |
| OSMR | oncostatin M receptor | 0.0286212 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0271649 |
| CALR | calreticulin | 0.0269474 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0266323 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0261001 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0255942 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0255261 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0255241 |
| RPL12 | ribosomal protein L12 | 0.0253176 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0252798 |
| HMGB2 | high mobility group box 2 | 0.024622 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0244293 |
| TMF1 | TATA element modulatory factor 1 | 0.0243598 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0241765 |
| RPL26 | ribosomal protein L26 | 0.0240142 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0237522 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0237248 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0236447 |
| EGR1 | early growth response 1 | 0.0233721 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0230363 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0224929 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0224781 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0224691 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0221876 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0221102 |
| RRBP1 | ribosome binding protein 1 | 0.0220537 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0217636 |
| VMP1 | vacuole membrane protein 1 | 0.0217014 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0210727 |
| DNER | delta/notch-like EGF repeat containing | 0.0208638 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.020782 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0207161 |
| RPL18 | ribosomal protein L18 | 0.0206721 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0206662 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0202891 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0198767 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0197972 |
| TPM3 | tropomyosin 3 | 0.0194471 |
| STC2 | stanniocalcin 2 | 0.0191785 |
| LOX | lysyl oxidase | 0.0191339 |
| KLF6 | Kruppel-like factor 6 | 0.0190498 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0190493 |
| RPS18 | ribosomal protein S18 | 0.0188363 |
| RPS15A | ribosomal protein S15a | 0.0187273 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.018634 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0185774 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0185118 |
| RPL37A | ribosomal protein L37a | 0.0185028 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0184489 |
| TMSB4X | thymosin beta 4, X-linked | 0.0184399 |
| TLN1 | talin 1 | 0.0182926 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0182908 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0182407 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0180778 |
| ATF4 | activating transcription factor 4 | 0.0180393 |
| SBF2 | SET binding factor 2 | 0.0179717 |
| RPL5 | ribosomal protein L5 | 0.0178243 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0176647 |
| EZR | ezrin | 0.0176022 |
| SET | SET nuclear proto-oncogene | 0.0174807 |
| RPS17 | ribosomal protein S17 | 0.0174134 |
| SCFD1 | sec1 family domain containing 1 | 0.0174056 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0173408 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0171078 |
| HDLBP | high density lipoprotein binding protein | 0.0170138 |
| ENO1 | enolase 1, (alpha) | 0.0169893 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0169012 |
| RPL36 | ribosomal protein L36 | 0.0168639 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0168283 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0166925 |
| MYO9A | myosin IXA | 0.0166757 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0166162 |
| RPL35A | ribosomal protein L35a | 0.016324 |
| CCDC47 | coiled-coil domain containing 47 | 0.0162853 |
| RACK1 | receptor for activated C kinase 1 | 0.0162044 |
| RAI1 | retinoic acid induced 1 | 0.0161734 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.417035 |
| FN1 | fibronectin 1 | -0.27379 |
| NDRG1 | N-myc downstream regulated 1 | -0.142497 |
| STC1 | stanniocalcin 1 | -0.12374 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0959611 |
| MMP1 | matrix metallopeptidase 1 | -0.0880432 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0829128 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0582273 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0572485 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0565918 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.056072 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0531095 |
| LDHA | lactate dehydrogenase A | -0.0502225 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0499478 |
| CD44 | CD44 molecule (Indian blood group) | -0.0472745 |
| POTEF | POTE ankyrin domain family, member F | -0.0469413 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0467457 |
| ADM | adrenomedullin | -0.0446534 |
| ATP13A3 | ATPase type 13A3 | -0.0435738 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0406188 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.038639 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0349591 |
| CALU | calumenin | -0.0347707 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0346494 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0330352 |
| PKM | pyruvate kinase, muscle | -0.0326629 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0320753 |
| HLA-B | major histocompatibility complex, class I, B | -0.0313292 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0301945 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0298499 |
| VEGFA | vascular endothelial growth factor A | -0.029249 |
| IER3 | immediate early response 3 | -0.0287628 |
| NPTX1 | neuronal pentraxin I | -0.0284014 |
| TMEM165 | transmembrane protein 165 | -0.0273862 |
| MMP12 | matrix metallopeptidase 12 | -0.0267805 |
| MYO10 | myosin X | -0.02677 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.02671 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0252519 |
| COL1A2 | collagen, type I, alpha 2 | -0.0249077 |
| MEIS1 | Meis homeobox 1 | -0.0245275 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0245175 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0244579 |
| WDR45B | WD repeat domain 45B | -0.0234798 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0227047 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0226185 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0225515 |
| IGF2 | insulin-like growth factor 2 | -0.0222283 |
| IL6 | interleukin 6 | -0.0213477 |
| AHNAK | AHNAK nucleoprotein | -0.021266 |
| SETD5 | SET domain containing 5 | -0.0211844 |
| FAM13A | family with sequence similarity 13, member A | -0.0211177 |
| UBC | ubiquitin C | -0.0207653 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0203143 |
| EMP1 | epithelial membrane protein 1 | -0.020179 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0194051 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0191027 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0187619 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0184401 |
| EHD2 | EH-domain containing 2 | -0.0183392 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0179735 |
| RHOA | ras homolog family member A | -0.017868 |
| RNF145 | ring finger protein 145 | -0.0177994 |
| RPS23 | ribosomal protein S23 | -0.0177374 |
| TAOK1 | TAO kinase 1 | -0.0175382 |
| DEK | DEK proto-oncogene | -0.0171542 |
| PHIP | pleckstrin homology domain interacting protein | -0.0171249 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0169492 |
| ANXA5 | annexin A5 | -0.0169146 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0168984 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0165948 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.01649 |
| SNX9 | sorting nexin 9 | -0.0164402 |
| FOSL1 | FOS-like antigen 1 | -0.0164283 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0160838 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0160783 |
| SFTPA2 | surfactant protein A2 | -0.0160474 |
| USP3 | ubiquitin specific peptidase 3 | -0.0158758 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0157232 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0156026 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0155961 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0155607 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0154245 |
| WASF2 | WAS protein family, member 2 | -0.0154081 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0153484 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0153277 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0151038 |
| KIF13A | kinesin family member 13A | -0.0150676 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -0.0149564 |
| CALD1 | caldesmon 1 | -0.0147113 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0146814 |
| RPLP0 | ribosomal protein, large, P0 | -0.0145391 |
| SPAG9 | sperm associated antigen 9 | -0.0142874 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0142508 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0142243 |
| CCNI | cyclin I | -0.0142191 |
| FAM162A | family with sequence similarity 162, member A | -0.0142114 |
| NUP58 | nucleoporin 58 | -0.0141811 |
| CLIC4 | chloride intracellular channel 4 | -0.0140609 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0140601 |
| MED13L | mediator complex subunit 13-like | -0.0140052 |
