| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/4413 |
| Similar Terms | |
| Downloads & Tools |
197 proteins with high or low expression in Nafamostat relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 2.43 |
| ZNF799 | zinc finger protein 799 | 0.8 |
| RPP21 | ribonuclease P/MRP 21kDa subunit | 0.71 |
| ZSCAN25 | zinc finger and SCAN domain containing 25 | 0.65 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 | 0.65 |
| GAS2L1 | growth arrest-specific 2 like 1 | 0.64 |
| SP4 | Sp4 transcription factor | 0.6 |
| TBRG1 | transforming growth factor beta regulator 1 | 0.58 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.57 |
| CCDC130 | coiled-coil domain containing 130 | 0.56 |
| STK19 | serine/threonine kinase 19 | 0.55 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | 0.55 |
| ABHD18 | abhydrolase domain containing 18 | 0.54 |
| NAA20 | N(alpha)-acetyltransferase 20, NatB catalytic subunit | 0.52 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.52 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | 0.5 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | 0.49 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.48 |
| UPRT | uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) | 0.45 |
| DDN | dendrin | 0.43 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | 0.42 |
| ZNF776 | zinc finger protein 776 | 0.42 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.42 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.42 |
| SUPT4H1 | suppressor of Ty 4 homolog 1 (S. cerevisiae) | 0.41 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.41 |
| MPV17L2 | MPV17 mitochondrial membrane protein-like 2 | 0.4 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 | 0.4 |
| TBC1D12 | TBC1 domain family, member 12 | 0.39 |
| ASB1 | ankyrin repeat and SOCS box containing 1 | 0.39 |
| TTC38 | tetratricopeptide repeat domain 38 | 0.39 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.39 |
| TSPAN31 | tetraspanin 31 | 0.39 |
| TTBK2 | tau tubulin kinase 2 | 0.38 |
| HIST2H3A | histone cluster 2, H3a | 0.38 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.38 |
| DPY30 | dpy-30 homolog (C. elegans) | 0.38 |
| LMLN | leishmanolysin-like (metallopeptidase M8 family) | 0.37 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.37 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | 0.37 |
| CFAP410 | cilia and flagella associated protein 410 | 0.36 |
| HBA1 | hemoglobin, alpha 1 | 0.35 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.35 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 0.34 |
| RHOB | ras homolog family member B | 0.34 |
| FBXO45 | F-box protein 45 | 0.34 |
| TOP1MT | topoisomerase (DNA) I, mitochondrial | 0.34 |
| C9ORF72 | chromosome 9 open reading frame 72 | 0.34 |
| PLAU | plasminogen activator, urokinase | 0.33 |
| RNF145 | ring finger protein 145 | 0.33 |
| MCTS2P | malignant T cell amplified sequence 2, pseudogene | 0.33 |
| C14ORF93 | chromosome 14 open reading frame 93 | 0.33 |
| UNC13C | unc-13 homolog C (C. elegans) | 0.32 |
| SCRN3 | secernin 3 | 0.32 |
| ZNF316 | zinc finger protein 316 | 0.32 |
| DBT | dihydrolipoamide branched chain transacylase E2 | 0.32 |
| ANK2 | ankyrin 2, neuronal | 0.32 |
| ZNF7 | zinc finger protein 7 | 0.31 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.31 |
| OBSL1 | obscurin-like 1 | 0.31 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.31 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.31 |
| SPHK2 | sphingosine kinase 2 | 0.31 |
| KLHL15 | kelch-like family member 15 | 0.3 |
| FGF2 | fibroblast growth factor 2 (basic) | 0.3 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.3 |
| ATF3 | activating transcription factor 3 | 0.3 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.3 |
| VAMP4 | vesicle-associated membrane protein 4 | 0.3 |
| KIAA1586 | KIAA1586 | 0.29 |
| LMX1B | LIM homeobox transcription factor 1, beta | 0.29 |
| NR2C2AP | nuclear receptor 2C2-associated protein | 0.29 |
| MRPS12 | mitochondrial ribosomal protein S12 | 0.29 |
| DGKE | diacylglycerol kinase, epsilon 64kDa | 0.29 |
| NAGS | N-acetylglutamate synthase | 0.29 |
| EFNB2 | ephrin-B2 | 0.29 |
| CHSY3 | chondroitin sulfate synthase 3 | 0.29 |
| SP1 | Sp1 transcription factor | 0.28 |
| DNLZ | DNL-type zinc finger | 0.28 |
| RNF26 | ring finger protein 26 | 0.28 |
| EME1 | essential meiotic structure-specific endonuclease 1 | 0.28 |
| TOR3A | torsin family 3, member A | 0.28 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.28 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | 0.28 |
| ZNF263 | zinc finger protein 263 | 0.28 |
| FBXO17 | F-box protein 17 | 0.27 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.27 |
| PRG4 | proteoglycan 4 | 0.27 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.27 |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit | 0.27 |
| RNF167 | ring finger protein 167 | 0.27 |
| RCE1 | Ras converting CAAX endopeptidase 1 | 0.27 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit | 0.27 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 | 0.27 |
| KALRN | kalirin, RhoGEF kinase | 0.27 |
| BMP8A | bone morphogenetic protein 8a | 0.27 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | 0.27 |
| HOXA10 | homeobox A10 | 0.27 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NEB | nebulin | -2.03 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase | -1.07 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | -0.64 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.63 |
| ACTBL2 | actin, beta-like 2 | -0.61 |
| CNTNAP3 | contactin associated protein-like 3 | -0.61 |
| IQCB1 | IQ motif containing B1 | -0.59 |
| SLC10A4 | solute carrier family 10, member 4 | -0.57 |
| MYOM2 | myomesin 2 | -0.56 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.55 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.52 |
| TANGO2 | transport and golgi organization 2 homolog (Drosophila) | -0.51 |
| ZNF714 | zinc finger protein 714 | -0.5 |
| SMIM19 | small integral membrane protein 19 | -0.49 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.48 |
| LRIG3 | leucine-rich repeats and immunoglobulin-like domains 3 | -0.43 |
| PSAP | prosaposin | -0.42 |
| F8A1 | coagulation factor VIII-associated 1 | -0.41 |
| CHKB | choline kinase beta | -0.41 |
| FTL | ferritin, light polypeptide | -0.39 |
| BDNF | brain-derived neurotrophic factor | -0.39 |
| MRFAP1 | Morf4 family associated protein 1 | -0.39 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.38 |
| IL10RB | interleukin 10 receptor, beta | -0.37 |
| LDB1 | LIM domain binding 1 | -0.36 |
| DENND5A | DENN/MADD domain containing 5A | -0.36 |
| ABHD17A | abhydrolase domain containing 17A | -0.36 |
| TSPOAP1 | TSPO associated protein 1 | -0.36 |
| TYSND1 | trypsin domain containing 1 | -0.36 |
| ATXN7L3 | ataxin 7-like 3 | -0.35 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.35 |
| BOK | BCL2-related ovarian killer | -0.35 |
| PAQR7 | progestin and adipoQ receptor family member VII | -0.35 |
| VAV1 | vav 1 guanine nucleotide exchange factor | -0.34 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.33 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.32 |
| MRVI1 | murine retrovirus integration site 1 homolog | -0.31 |
| SLC39A11 | solute carrier family 39, member 11 | -0.31 |
| PIP | prolactin-induced protein | -0.31 |
| DOCK11 | dedicator of cytokinesis 11 | -0.31 |
| SH3BP5L | SH3-binding domain protein 5-like | -0.31 |
| CCDC158 | coiled-coil domain containing 158 | -0.3 |
| TJAP1 | tight junction associated protein 1 (peripheral) | -0.3 |
| RBL2 | retinoblastoma-like 2 | -0.3 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | -0.3 |
| ZMYM6 | zinc finger, MYM-type 6 | -0.29 |
| ZNF526 | zinc finger protein 526 | -0.29 |
| NF1 | neurofibromin 1 | -0.29 |
| MIIP | migration and invasion inhibitory protein | -0.29 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -0.29 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | -0.29 |
| ZBTB6 | zinc finger and BTB domain containing 6 | -0.28 |
| CCNQ | cyclin Q | -0.28 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.28 |
| SMOX | spermine oxidase | -0.28 |
| TNS1 | tensin 1 | -0.27 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.27 |
| BHLHA15 | basic helix-loop-helix family, member a15 | -0.27 |
| PCGF3 | polycomb group ring finger 3 | -0.27 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.27 |
| DMWD | dystrophia myotonica, WD repeat containing | -0.27 |
| KIF21B | kinesin family member 21B | -0.26 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | -0.26 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.25 |
| ATP9B | ATPase, class II, type 9B | -0.25 |
| BMP4 | bone morphogenetic protein 4 | -0.25 |
| ZNF195 | zinc finger protein 195 | -0.25 |
| ENO1 | enolase 1, (alpha) | -0.25 |
| ZNF557 | zinc finger protein 557 | -0.25 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.24 |
| ATP5IF1 | ATP synthase inhibitory factor subunit 1 | -0.24 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.24 |
| RAMAC | RNA guanine-7 methyltransferase activating subunit | -0.24 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.24 |
| PPT2 | palmitoyl-protein thioesterase 2 | -0.24 |
| TSPAN3 | tetraspanin 3 | -0.24 |
| HGFAC | HGF activator | -0.23 |
| ERICH1 | glutamate-rich 1 | -0.23 |
| JRK | Jrk homolog (mouse) | -0.23 |
| S100A6 | S100 calcium binding protein A6 | -0.23 |
| ACTB | actin, beta | -0.23 |
| DST | dystonin | -0.23 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.23 |
| FAM110A | family with sequence similarity 110, member A | -0.23 |
| FAM3A | family with sequence similarity 3, member A | -0.23 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.23 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | -0.23 |
| ABHD2 | abhydrolase domain containing 2 | -0.23 |
| PTMS | parathymosin | -0.23 |
| KLF13 | Kruppel-like factor 13 | -0.23 |
| BTBD11 | BTB (POZ) domain containing 11 | -0.22 |
| CASTOR2 | cytosolic arginine sensor for mTORC1 subunit 2 | -0.22 |
| TMEM97 | transmembrane protein 97 | -0.22 |
| GATAD1 | GATA zinc finger domain containing 1 | -0.22 |
| DES | desmin | -0.22 |
| TMEM208 | transmembrane protein 208 | -0.22 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | -0.22 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.22 |
| MRPL33 | mitochondrial ribosomal protein L33 | -0.22 |
