Naproxen Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes. (Chemical Entities of Biological Interest Ontology, CHEBI_7476)
External Link http://www.drugbank.ca/drugs/DB00788
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Genes

8 interacting proteins for the Naproxen drug from the curated DrugBank Drug Targets dataset.

Symbol Name
ALB albumin
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLCO1A2 solute carrier organic anion transporter family, member 1A2
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7