| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.18419 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.16299 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.140873 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.134306 |
| COL1A1 | collagen, type I, alpha 1 | 0.109355 |
| COL3A1 | collagen, type III, alpha 1 | 0.102562 |
| MSI2 | musashi RNA-binding protein 2 | 0.0704357 |
| RPL4 | ribosomal protein L4 | 0.0670599 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0639841 |
| VGF | VGF nerve growth factor inducible | 0.0635672 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0634419 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0617498 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0592744 |
| UBC | ubiquitin C | 0.0588962 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0577168 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0561379 |
| PCBP2 | poly(rC) binding protein 2 | 0.0554654 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0546129 |
| AHNAK | AHNAK nucleoprotein | 0.0544014 |
| HMGB2 | high mobility group box 2 | 0.0537491 |
| ACTG1 | actin gamma 1 | 0.0528675 |
| PKM | pyruvate kinase, muscle | 0.0520558 |
| MED13L | mediator complex subunit 13-like | 0.0498039 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0493589 |
| RPS27A | ribosomal protein S27a | 0.0492197 |
| POTEF | POTE ankyrin domain family, member F | 0.0464376 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0463113 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0458394 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0453453 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0437467 |
| VMP1 | vacuole membrane protein 1 | 0.0436909 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0432328 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0427878 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0426138 |
| SEPTIN9 | septin 9 | 0.0423987 |
| GOLGA4 | golgin A4 | 0.0422124 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0414737 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0407308 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0407275 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0400013 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0398954 |
| HSPA8 | heat shock 70kDa protein 8 | 0.039868 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0392426 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0387911 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0381416 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0381134 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0373154 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0370434 |
| ENO1 | enolase 1, (alpha) | 0.0369632 |
| RACK1 | receptor for activated C kinase 1 | 0.0361696 |
| SET | SET nuclear proto-oncogene | 0.0356188 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0352357 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0348969 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0345376 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0343822 |
| FLNA | filamin A, alpha | 0.0342404 |
| RHOA | ras homolog family member A | 0.0340166 |
| NCKAP1 | NCK-associated protein 1 | 0.0338232 |
| CALR | calreticulin | 0.0334252 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0332851 |
| FAM107B | family with sequence similarity 107, member B | 0.0330647 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0319554 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0318249 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0314966 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0312448 |
| MATR3 | matrin 3 | 0.0310566 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0310418 |
| PTMA | prothymosin, alpha | 0.0309113 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0305413 |
| LPIN1 | lipin 1 | 0.0301756 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.029712 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0293561 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0291409 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0290951 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0286889 |
| RPL3 | ribosomal protein L3 | 0.0284151 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0283805 |
| SMAD3 | SMAD family member 3 | 0.0282624 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0281312 |
| TXNRD1 | thioredoxin reductase 1 | 0.0281247 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0280353 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0278314 |
| PCNX1 | pecanex 1 | 0.0276341 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0274251 |
| ATXN2 | ataxin 2 | 0.0273682 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0272953 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0272329 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.02708 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0270196 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0269981 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0269963 |
| VEGFA | vascular endothelial growth factor A | 0.0269488 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0269363 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0265867 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0265467 |
| HDGF | hepatoma-derived growth factor | 0.0264243 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0263342 |
| IPO7 | importin 7 | 0.0261773 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0260284 |
| QKI | QKI, KH domain containing, RNA binding | 0.0259867 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.27865 |
| IGF2 | insulin-like growth factor 2 | -0.0935489 |
| RPL38 | ribosomal protein L38 | -0.0823043 |
| SYT1 | synaptotagmin I | -0.0785028 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0579211 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0564314 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0550111 |
| BPTF | bromodomain PHD finger transcription factor | -0.0517147 |
| NRG1 | neuregulin 1 | -0.049539 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.049018 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0484991 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0481084 |
| TLE4 | transducin-like enhancer of split 4 | -0.0459135 |
| RPLP1 | ribosomal protein, large, P1 | -0.0458391 |
| CLTC | clathrin, heavy chain (Hc) | -0.0455631 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.044801 |
| PHF14 | PHD finger protein 14 | -0.0443654 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0441687 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0413605 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.0396881 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0381508 |
| MBTD1 | mbt domain containing 1 | -0.0378798 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0377308 |
| RPL35A | ribosomal protein L35a | -0.0374296 |
| H3-3B | H3.3 histone B | -0.0372108 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0367255 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.035811 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0357106 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0355165 |
| NREP | neuronal regeneration related protein | -0.0350468 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0349824 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0346021 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0340317 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0338252 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0330874 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0324772 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0323932 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0313749 |
| RPS24 | ribosomal protein S24 | -0.030834 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0307761 |
| SMYD3 | SET and MYND domain containing 3 | -0.030771 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0301718 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.029966 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0297213 |
| CENPF | centromere protein F, 350/400kDa | -0.0291193 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0290081 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0289873 |
| DPH6 | diphthamine biosynthesis 6 | -0.0289592 |
| NEK7 | NIMA-related kinase 7 | -0.0287524 |
| RPL12 | ribosomal protein L12 | -0.0281423 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0277805 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0277389 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0275204 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.02749 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0271998 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0271003 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0266364 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0265462 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0264958 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | -0.0262397 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | -0.0262073 |
| ERBIN | erbb2 interacting protein | -0.0260589 |
| PHF21A | PHD finger protein 21A | -0.0257152 |
| RBMX | RNA binding motif protein, X-linked | -0.0257132 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0256159 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0255502 |
| B2M | beta-2-microglobulin | -0.0252808 |
| BSG | basigin (Ok blood group) | -0.025107 |
| INTU | inturned planar cell polarity protein | -0.0250603 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0245392 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0245187 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0244879 |
| FHIT | fragile histidine triad | -0.0243768 |
| PRTG | protogenin | -0.0241714 |
| PIK3C2G | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma | -0.0239688 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0238924 |
| PHOX2B | paired-like homeobox 2b | -0.0237074 |
| TFB1M | transcription factor B1, mitochondrial | -0.0235741 |
| PRR11 | proline rich 11 | -0.0234245 |
| NBEA | neurobeachin | -0.02342 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | -0.0233505 |
| RPL19 | ribosomal protein L19 | -0.0233342 |
| STC1 | stanniocalcin 1 | -0.0233333 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0232696 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0230636 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.023061 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0229701 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.022941 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0228617 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0227156 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0226228 |
| TENM3 | teneurin transmembrane protein 3 | -0.0225684 |
| CDC27 | cell division cycle 27 | -0.0224941 |
| FNBP1 | formin binding protein 1 | -0.0223907 |
| RPS5 | ribosomal protein S5 | -0.0222288 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0220309 |
| SON | SON DNA binding protein | -0.0216459 |
| PCDH10 | protocadherin 10 | -0.0214749 |
| RPS11 | ribosomal protein S11 | -0.0211657 |
| TMEM263 | transmembrane protein 263 | -0.0208652 |
