| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.145882 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0955646 |
| PHF3 | PHD finger protein 3 | 0.0887433 |
| RUNX1 | runt-related transcription factor 1 | 0.084772 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0752811 |
| IFNGR1 | interferon gamma receptor 1 | 0.0715738 |
| UBC | ubiquitin C | 0.0671863 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0668566 |
| RNF43 | ring finger protein 43 | 0.0665253 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0626899 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0621534 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0599269 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.05965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0571437 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0548985 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.054758 |
| MLPH | melanophilin | 0.0540909 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0540188 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0533774 |
| AHNAK | AHNAK nucleoprotein | 0.053008 |
| PRELID2 | PRELI domain containing 2 | 0.0523617 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0491072 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0466639 |
| RAD51B | RAD51 paralog B | 0.0462615 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0459486 |
| CANX | calnexin | 0.0457785 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0449158 |
| NCKAP5 | NCK-associated protein 5 | 0.044647 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0433535 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0432196 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0428284 |
| DSPP | dentin sialophosphoprotein | 0.0427036 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0420977 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0417732 |
| H1-0 | H1.0 linker histone | 0.0408829 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0407236 |
| FAT1 | FAT atypical cadherin 1 | 0.0401261 |
| AOPEP | aminopeptidase O (putative) | 0.0396727 |
| SBF2 | SET binding factor 2 | 0.0392385 |
| HDAC4 | histone deacetylase 4 | 0.0386359 |
| MKI67 | marker of proliferation Ki-67 | 0.0385317 |
| MEIS2 | Meis homeobox 2 | 0.0384784 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0384127 |
| FOXP1 | forkhead box P1 | 0.0382201 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0373909 |
| RBM39 | RNA binding motif protein 39 | 0.0373877 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0372646 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0371719 |
| RRBP1 | ribosome binding protein 1 | 0.0368398 |
| RPS3 | ribosomal protein S3 | 0.0362948 |
| UBAC2 | UBA domain containing 2 | 0.035508 |
| DIAPH3 | diaphanous-related formin 3 | 0.0354072 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0352066 |
| TPR | translocated promoter region, nuclear basket protein | 0.0351758 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0349694 |
| EHF | ets homologous factor | 0.0349004 |
| AHI1 | Abelson helper integration site 1 | 0.034843 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0346409 |
| PTMA | prothymosin, alpha | 0.0346242 |
| CENPF | centromere protein F, 350/400kDa | 0.0345795 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.034436 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0343256 |
| HDLBP | high density lipoprotein binding protein | 0.0340796 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0338949 |
| RPS6 | ribosomal protein S6 | 0.0338024 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.033734 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.03373 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0336228 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0335229 |
| RBM26 | RNA binding motif protein 26 | 0.0331784 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.0329945 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0320033 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0317532 |
| STK24 | serine/threonine kinase 24 | 0.030946 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0309031 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0307935 |
| OGA | O-GlcNAcase | 0.0304696 |
| RPL26 | ribosomal protein L26 | 0.0299534 |
| APP | amyloid beta (A4) precursor protein | 0.0297554 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.029584 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0294082 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0293854 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0287157 |
| TC2N | tandem C2 domains, nuclear | 0.0284004 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0283107 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0281164 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0278587 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0278116 |
| RBM33 | RNA binding motif protein 33 | 0.0277162 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0275712 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0273845 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0271941 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0270829 |
| RPS27A | ribosomal protein S27a | 0.0269605 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0269483 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0268633 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0267562 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0267445 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0267258 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0265886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | -0.132892 |
| LMO7 | LIM domain 7 | -0.115584 |
| ANXA2 | annexin A2 | -0.100209 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0990622 |
| B2M | beta-2-microglobulin | -0.0902267 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0888989 |
| ERBIN | erbb2 interacting protein | -0.0810141 |
| LYZ | lysozyme | -0.0789418 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0691322 |
| RNF213 | ring finger protein 213 | -0.0687825 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0666231 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0654791 |
| INTS6 | integrator complex subunit 6 | -0.0635632 |
| RIGI | RNA sensor RIG-I | -0.0613036 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0603013 |
| VCL | vinculin | -0.0589967 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0586859 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0571412 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.055341 |
| TJP1 | tight junction protein 1 | -0.0530928 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0504213 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0504194 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0497612 |
| MX2 | MX dynamin-like GTPase 2 | -0.0497231 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0485721 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0483609 |
| MYO1E | myosin IE | -0.0482625 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0481037 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.046754 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0465897 |
| AREG | amphiregulin | -0.0459864 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0429318 |
| NPSR1 | neuropeptide S receptor 1 | -0.0426029 |
| UBAP2 | ubiquitin associated protein 2 | -0.0424305 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0417081 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0408829 |
| PERP | PERP, TP53 apoptosis effector | -0.038891 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0381898 |
| VMP1 | vacuole membrane protein 1 | -0.037903 |
| MCL1 | myeloid cell leukemia 1 | -0.037581 |
| EZR | ezrin | -0.0374514 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0354586 |
| LCN2 | lipocalin 2 | -0.0352572 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0345647 |
| PLIN2 | perilipin 2 | -0.0344804 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0343529 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0333666 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0329312 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0324961 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0314396 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0309406 |
| DUSP10 | dual specificity phosphatase 10 | -0.0306747 |
| EFNB2 | ephrin-B2 | -0.0305799 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0302361 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0300443 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.030002 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0298012 |
| MAGT1 | magnesium transporter 1 | -0.0297126 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0296923 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0295772 |
| BCL2L1 | BCL2-like 1 | -0.029494 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.029364 |
| SPAG9 | sperm associated antigen 9 | -0.0292707 |
| NABP1 | nucleic acid binding protein 1 | -0.0290167 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0289396 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0284148 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0278598 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0273985 |
| PMP22 | peripheral myelin protein 22 | -0.0273901 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0272429 |
| PLSCR2 | phospholipid scramblase 2 | -0.0267012 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0265781 |
| OXSR1 | oxidative stress responsive 1 | -0.0264313 |
| LAMA4 | laminin, alpha 4 | -0.026261 |
| KYNU | kynureninase | -0.0261593 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0255659 |
| LIMA1 | LIM domain and actin binding 1 | -0.0254804 |
| RBM47 | RNA binding motif protein 47 | -0.0254449 |
| PRKCA | protein kinase C, alpha | -0.025439 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0252708 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0252247 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0251689 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0248581 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0248445 |
| GK | glycerol kinase | -0.0245095 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0244743 |
| HKDC1 | hexokinase domain containing 1 | -0.0242783 |
| TRIB1 | tribbles pseudokinase 1 | -0.0240073 |
| CST3 | cystatin C | -0.02383 |
| SDCBP | syndecan binding protein (syntenin) | -0.0236363 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0235769 |
| KRT19 | keratin 19, type I | -0.0233933 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0233748 |
| HLA-A | major histocompatibility complex, class I, A | -0.0231029 |
| ANXA1 | annexin A1 | -0.0230291 |
| MT2A | metallothionein 2A | -0.0228642 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0227608 |
| LIPH | lipase, member H | -0.022566 |
| S100A6 | S100 calcium binding protein A6 | -0.0224487 |
| TNS4 | tensin 4 | -0.0220794 |
