| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.248156 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.158682 |
| PTMA | prothymosin, alpha | 0.145333 |
| RPS6 | ribosomal protein S6 | 0.128054 |
| RPS2 | ribosomal protein S2 | 0.107697 |
| TXNIP | thioredoxin interacting protein | 0.0951885 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.094624 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0912659 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0810971 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0751576 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0674843 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0614053 |
| EZR | ezrin | 0.0591206 |
| H1-0 | H1.0 linker histone | 0.0562565 |
| RBM39 | RNA binding motif protein 39 | 0.054187 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0526553 |
| AHNAK | AHNAK nucleoprotein | 0.0520554 |
| AREG | amphiregulin | 0.0519354 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0517163 |
| RPS12 | ribosomal protein S12 | 0.0504051 |
| RPL4 | ribosomal protein L4 | 0.0503596 |
| EREG | epiregulin | 0.0496641 |
| CALR | calreticulin | 0.0477446 |
| ONECUT3 | one cut homeobox 3 | 0.0474024 |
| MUC13 | mucin 13, cell surface associated | 0.0465564 |
| PCBP2 | poly(rC) binding protein 2 | 0.0448505 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0443184 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0438738 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0421137 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0418503 |
| FAM13A | family with sequence similarity 13, member A | 0.0416972 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0416439 |
| RNF43 | ring finger protein 43 | 0.0416004 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.041532 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0412711 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0395471 |
| BRD2 | bromodomain containing 2 | 0.0391953 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0387797 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.038769 |
| TNS4 | tensin 4 | 0.0385365 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.038463 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0383088 |
| VMP1 | vacuole membrane protein 1 | 0.0375963 |
| RNF145 | ring finger protein 145 | 0.0370854 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0370313 |
| H1-4 | H1.4 linker histone, cluster member | 0.0368848 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.036869 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0367824 |
| TLN1 | talin 1 | 0.0366607 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0362081 |
| CENPF | centromere protein F, 350/400kDa | 0.0358937 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0358363 |
| PNN | pinin, desmosome associated protein | 0.0357802 |
| DUSP4 | dual specificity phosphatase 4 | 0.0357685 |
| PHIP | pleckstrin homology domain interacting protein | 0.0353227 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0351011 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0350069 |
| RPS17 | ribosomal protein S17 | 0.0339377 |
| PDZD8 | PDZ domain containing 8 | 0.0337496 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0337014 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0335273 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0333327 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0332265 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0331664 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0330053 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0329549 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0327535 |
| MKI67 | marker of proliferation Ki-67 | 0.0326924 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0325917 |
| GOLGA4 | golgin A4 | 0.0324715 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0316128 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0312355 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0307042 |
| EGFR | epidermal growth factor receptor | 0.0306431 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0306158 |
| FOXJ3 | forkhead box J3 | 0.0306047 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0304121 |
| VEGFA | vascular endothelial growth factor A | 0.0292227 |
| SMYD3 | SET and MYND domain containing 3 | 0.0291919 |
| TMF1 | TATA element modulatory factor 1 | 0.0287204 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.028419 |
| PAPOLA | poly(A) polymerase alpha | 0.0283956 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0282061 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0280007 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0279408 |
| HMGB2 | high mobility group box 2 | 0.0279349 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0275401 |
| SET | SET nuclear proto-oncogene | 0.0274324 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0271532 |
| DSPP | dentin sialophosphoprotein | 0.0270712 |
| TPM3 | tropomyosin 3 | 0.0269501 |
| MYO10 | myosin X | 0.0269006 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0268259 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0262566 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0260393 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0258984 |
| RPL26 | ribosomal protein L26 | 0.0257713 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0256785 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0254953 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0253212 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.145402 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.125199 |
| NPSR1 | neuropeptide S receptor 1 | -0.104538 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0898982 |
| PIGR | polymeric immunoglobulin receptor | -0.0810843 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0778012 |
| KRT18 | keratin 18, type I | -0.0753607 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0749568 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0648993 |
| RPL35A | ribosomal protein L35a | -0.0619061 |
| PGK1 | phosphoglycerate kinase 1 | -0.0618946 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0610019 |
| TPM4 | tropomyosin 4 | -0.0575375 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0533793 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0523867 |
| POTEF | POTE ankyrin domain family, member F | -0.0521923 |
| LDHA | lactate dehydrogenase A | -0.0513445 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0505937 |
| S100A6 | S100 calcium binding protein A6 | -0.0491134 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0470194 |
| IER3 | immediate early response 3 | -0.0455824 |
| ANXA2 | annexin A2 | -0.0454868 |
| AGR2 | anterior gradient 2 | -0.0454786 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0447379 |
| HMGA1 | high mobility group AT-hook 1 | -0.0446221 |
| RPLP0 | ribosomal protein, large, P0 | -0.0444136 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0422051 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0420139 |
| MUC17 | mucin 17, cell surface associated | -0.0420112 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0419878 |
| CANX | calnexin | -0.0416823 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0413294 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0397888 |
| EPCAM | epithelial cell adhesion molecule | -0.0397296 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0394239 |
| RPS24 | ribosomal protein S24 | -0.0387673 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0385638 |
| ITGA6 | integrin, alpha 6 | -0.0382447 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0377429 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.035671 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0356682 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0355911 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0347522 |
| CCND1 | cyclin D1 | -0.0346676 |
| S100A14 | S100 calcium binding protein A14 | -0.034192 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.032819 |
| KLK10 | kallikrein-related peptidase 10 | -0.0321837 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0318166 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0310932 |
| KRT19 | keratin 19, type I | -0.0302745 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0302677 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0302297 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0300837 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.030047 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0292039 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0288257 |
| ENO1 | enolase 1, (alpha) | -0.0286827 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0280925 |
| VCL | vinculin | -0.0280047 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0275229 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.027291 |
| TFF1 | trefoil factor 1 | -0.0272804 |
| ANXA3 | annexin A3 | -0.0270102 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0268405 |
| ZNF33A | zinc finger protein 33A | -0.0266257 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0260466 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.0257849 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0256448 |
| FTL | ferritin, light polypeptide | -0.0256338 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0255042 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0253533 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0247902 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0247792 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0247275 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0246505 |
| TFRC | transferrin receptor | -0.0243243 |
| ZNF518A | zinc finger protein 518A | -0.0242993 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0242032 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0240593 |
| ZNF562 | zinc finger protein 562 | -0.023974 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.023878 |
| SCFD1 | sec1 family domain containing 1 | -0.0237288 |
| CSTB | cystatin B (stefin B) | -0.0236617 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0235796 |
| RPS5 | ribosomal protein S5 | -0.0234539 |
| RPL23 | ribosomal protein L23 | -0.0231326 |
| ARF4 | ADP-ribosylation factor 4 | -0.0227761 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0222116 |
| FBXO11 | F-box protein 11 | -0.0216819 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0216778 |
| CD46 | CD46 molecule, complement regulatory protein | -0.021602 |
| CFAP73 | cilia and flagella associated protein 73 | -0.0215271 |
| PERP | PERP, TP53 apoptosis effector | -0.0213319 |
| LAMA4 | laminin, alpha 4 | -0.021263 |
| RNF217 | ring finger protein 217 | -0.0212393 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0212214 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0211918 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0211722 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0211551 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0210858 |
