| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.220693 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.196263 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.147112 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.130125 |
| UBC | ubiquitin C | 0.125701 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.113474 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0993838 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0970564 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0942765 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0912433 |
| RAI1 | retinoic acid induced 1 | 0.0895787 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0892146 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.085133 |
| PCBP2 | poly(rC) binding protein 2 | 0.0834647 |
| TXNRD1 | thioredoxin reductase 1 | 0.0810775 |
| DST | dystonin | 0.0789848 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0788553 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0787002 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0773511 |
| RPS12 | ribosomal protein S12 | 0.0734194 |
| EREG | epiregulin | 0.071039 |
| RPS27A | ribosomal protein S27a | 0.0699949 |
| CENPF | centromere protein F, 350/400kDa | 0.0691345 |
| SET | SET nuclear proto-oncogene | 0.0680402 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0672293 |
| RPS2 | ribosomal protein S2 | 0.0668828 |
| RPS6 | ribosomal protein S6 | 0.0657891 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0637081 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0625487 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.058697 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0556119 |
| AHNAK | AHNAK nucleoprotein | 0.0546838 |
| RTN4 | reticulon 4 | 0.0534364 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0534165 |
| RACK1 | receptor for activated C kinase 1 | 0.0528526 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0527527 |
| TPM3 | tropomyosin 3 | 0.0527447 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0524332 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0517368 |
| FLNB | filamin B, beta | 0.0497629 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0491164 |
| RPS8 | ribosomal protein S8 | 0.0487826 |
| CAPRIN2 | caprin family member 2 | 0.0480871 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0476843 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0475193 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0462899 |
| HDGF | hepatoma-derived growth factor | 0.0453142 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0452145 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0450387 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0450303 |
| WDR43 | WD repeat domain 43 | 0.0447983 |
| RPL4 | ribosomal protein L4 | 0.0442399 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0410191 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.040117 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0386159 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0385438 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.038543 |
| PLK2 | polo-like kinase 2 | 0.038118 |
| VMP1 | vacuole membrane protein 1 | 0.0376183 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0368449 |
| CCNL1 | cyclin L1 | 0.0368126 |
| RPL5 | ribosomal protein L5 | 0.0365705 |
| DSTN | destrin (actin depolymerizing factor) | 0.0363235 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0349537 |
| MCL1 | myeloid cell leukemia 1 | 0.0348492 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0347889 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0341085 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0341031 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.03373 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0335467 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0333767 |
| RPL26 | ribosomal protein L26 | 0.0330373 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0327592 |
| RASAL2 | RAS protein activator like 2 | 0.0323637 |
| NONO | non-POU domain containing, octamer-binding | 0.0323439 |
| TUBA1B | tubulin, alpha 1b | 0.031451 |
| RBM39 | RNA binding motif protein 39 | 0.031354 |
| FNIP1 | folliculin interacting protein 1 | 0.0312731 |
| XPO1 | exportin 1 | 0.0312046 |
| JUN | jun proto-oncogene | 0.031158 |
| MKI67 | marker of proliferation Ki-67 | 0.0310256 |
| RHOA | ras homolog family member A | 0.0309891 |
| EZR | ezrin | 0.0308317 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0306653 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0305163 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0304685 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0304434 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0297357 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0296287 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0295122 |
| RASA2 | RAS p21 protein activator 2 | 0.0293582 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0292177 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0291911 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 0.0291312 |
| GOLGA4 | golgin A4 | 0.0286752 |
| PAPOLA | poly(A) polymerase alpha | 0.0284258 |
| SMAD3 | SMAD family member 3 | 0.0283189 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0282034 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0281166 |
| RPL37 | ribosomal protein L37 | 0.0280814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.169589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137605 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.136296 |
| MT2A | metallothionein 2A | -0.0772368 |
| TP63 | tumor protein p63 | -0.0748379 |
| RPL35A | ribosomal protein L35a | -0.0683038 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0675259 |
| HLA-B | major histocompatibility complex, class I, B | -0.0611804 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0583776 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0493013 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0461998 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0459716 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0457947 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0442973 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0440558 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0439699 |
| FTL | ferritin, light polypeptide | -0.0435539 |
| RNF213 | ring finger protein 213 | -0.0433702 |
| KPNB1 | karyopherin (importin) beta 1 | -0.043042 |
| KLF6 | Kruppel-like factor 6 | -0.0406262 |
| FBXO11 | F-box protein 11 | -0.0398925 |
| ZNF217 | zinc finger protein 217 | -0.0382696 |
| H1-0 | H1.0 linker histone | -0.037927 |
| BSG | basigin (Ok blood group) | -0.0374952 |
| HMGA1 | high mobility group AT-hook 1 | -0.0367789 |
| GNAS | GNAS complex locus | -0.0362833 |
| RPS4X | ribosomal protein S4, X-linked | -0.0350826 |
| NDRG1 | N-myc downstream regulated 1 | -0.0346927 |
| PKM | pyruvate kinase, muscle | -0.0338296 |
| RPS24 | ribosomal protein S24 | -0.0338001 |
| DEK | DEK proto-oncogene | -0.032746 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0325739 |
| ARF1 | ADP-ribosylation factor 1 | -0.0324143 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.032099 |
| RPLP1 | ribosomal protein, large, P1 | -0.0320053 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0315888 |
| DENND5B | DENN/MADD domain containing 5B | -0.0308456 |
| RIGI | RNA sensor RIG-I | -0.0302372 |
| TFRC | transferrin receptor | -0.0295495 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.029288 |
| PGK1 | phosphoglycerate kinase 1 | -0.0292111 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0289704 |
| VCL | vinculin | -0.0287658 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0284162 |
| RLF | rearranged L-myc fusion | -0.0283572 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0278364 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0276706 |
| TUT4 | terminal uridylyl transferase 4 | -0.0269108 |
| NF1 | neurofibromin 1 | -0.0267197 |
| SEPTIN7 | septin 7 | -0.0265283 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0264997 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0260374 |
| CADM2 | cell adhesion molecule 2 | -0.0260258 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0256305 |
| RPS28 | ribosomal protein S28 | -0.0255608 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0249675 |
| RPL38 | ribosomal protein L38 | -0.0249395 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0249259 |
| KLHL24 | kelch-like family member 24 | -0.024299 |
| MORF4L2 | mortality factor 4 like 2 | -0.0241901 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0241475 |
| WDR45B | WD repeat domain 45B | -0.0241033 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0240594 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0238495 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0230462 |
| CUX1 | cut-like homeobox 1 | -0.0230031 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.022857 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0226207 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0223929 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0223729 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0222216 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0219859 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0219327 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0217825 |
| RUNX1 | runt-related transcription factor 1 | -0.0216505 |
| APP | amyloid beta (A4) precursor protein | -0.0215571 |
| CD109 | CD109 molecule | -0.0215152 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0214153 |
| TPM4 | tropomyosin 4 | -0.0213846 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0212813 |
| RNF216 | ring finger protein 216 | -0.0209521 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.020845 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.020778 |
| CUL4B | cullin 4B | -0.0207483 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0206895 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.020591 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0205636 |
| SNX14 | sorting nexin 14 | -0.0205492 |
| RPL34 | ribosomal protein L34 | -0.0205084 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0205034 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0204969 |
| UBAP2L | ubiquitin associated protein 2-like | -0.02045 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0203911 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0201495 |
| SMYD3 | SET and MYND domain containing 3 | -0.0200496 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0200005 |
| RPLP0 | ribosomal protein, large, P0 | -0.0197393 |
| CAVIN1 | caveolae associated protein 1 | -0.0194299 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0192982 |
| EXOC4 | exocyst complex component 4 | -0.0191571 |
