| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.178915 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.172657 |
| UBC | ubiquitin C | 0.157596 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.148435 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.127157 |
| VIM | vimentin | 0.116004 |
| RBM39 | RNA binding motif protein 39 | 0.101811 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0997397 |
| GOLGA4 | golgin A4 | 0.0946236 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0906111 |
| TMSB10 | thymosin beta 10 | 0.0882125 |
| LOX | lysyl oxidase | 0.0805324 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0793864 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0773728 |
| AHNAK | AHNAK nucleoprotein | 0.0660733 |
| RPL4 | ribosomal protein L4 | 0.0657865 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.063829 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0611654 |
| ETV6 | ets variant 6 | 0.0555603 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0529114 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0516576 |
| OGA | O-GlcNAcase | 0.0510912 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0509995 |
| SMAD3 | SMAD family member 3 | 0.0506845 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0500096 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0490274 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0488998 |
| FLNB | filamin B, beta | 0.0484981 |
| CALU | calumenin | 0.0480095 |
| FAM20C | family with sequence similarity 20, member C | 0.0467378 |
| RPS27A | ribosomal protein S27a | 0.046605 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0464163 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.046162 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0460941 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0460708 |
| KYNU | kynureninase | 0.0455093 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0449606 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.044913 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0441737 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0437972 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0435474 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0435072 |
| FNIP1 | folliculin interacting protein 1 | 0.0433064 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.042828 |
| APP | amyloid beta (A4) precursor protein | 0.0420108 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0416445 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0416276 |
| FAM13A | family with sequence similarity 13, member A | 0.0415442 |
| RUNX1 | runt-related transcription factor 1 | 0.0410044 |
| RAI14 | retinoic acid induced 14 | 0.0384046 |
| PTMA | prothymosin, alpha | 0.03837 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0373616 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0371849 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0369354 |
| RPS2 | ribosomal protein S2 | 0.0365562 |
| FBXO32 | F-box protein 32 | 0.0360358 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0351817 |
| MLPH | melanophilin | 0.0348692 |
| JUN | jun proto-oncogene | 0.0347324 |
| ADD3 | adducin 3 (gamma) | 0.0345709 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0340147 |
| PRELID2 | PRELI domain containing 2 | 0.033553 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.033266 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0330895 |
| YEATS2 | YEATS domain containing 2 | 0.0329936 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0329849 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0324426 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0321013 |
| CALR | calreticulin | 0.031933 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.031704 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0316855 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.031485 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0311955 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.031184 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.030907 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0308967 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0305379 |
| SYAP1 | synapse associated protein 1 | 0.0303231 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0300859 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.029471 |
| GPX3 | glutathione peroxidase 3 | 0.0293921 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0291572 |
| SEC24A | SEC24 family member A | 0.0290747 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0288997 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.028736 |
| HDLBP | high density lipoprotein binding protein | 0.0287093 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0286995 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0285452 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0282603 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0279885 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0279538 |
| FMNL2 | formin-like 2 | 0.0278786 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0278474 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0277385 |
| SBF2 | SET binding factor 2 | 0.0276423 |
| RND3 | Rho family GTPase 3 | 0.0276199 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0275917 |
| ENO1 | enolase 1, (alpha) | 0.0274385 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0273533 |
| TMEM263 | transmembrane protein 263 | 0.0272827 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.179588 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.117534 |
| RPL35A | ribosomal protein L35a | -0.116273 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113835 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0906013 |
| FTL | ferritin, light polypeptide | -0.0883567 |
| RPLP1 | ribosomal protein, large, P1 | -0.0867623 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0801512 |
| NDRG1 | N-myc downstream regulated 1 | -0.0754775 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0574457 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0534736 |
| HMGA1 | high mobility group AT-hook 1 | -0.0506537 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0495318 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0468851 |
| RPLP0 | ribosomal protein, large, P0 | -0.0458294 |
| B2M | beta-2-microglobulin | -0.0445552 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0442371 |
| RPS24 | ribosomal protein S24 | -0.0439033 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0436241 |
| NRG1 | neuregulin 1 | -0.0393 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0384141 |
| CDH13 | cadherin 13 | -0.0382694 |
| EFNA5 | ephrin-A5 | -0.0365036 |
| PLIN2 | perilipin 2 | -0.0361908 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0360674 |
| DPYD | dihydropyrimidine dehydrogenase | -0.035805 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0357449 |
| CD44 | CD44 molecule (Indian blood group) | -0.0353514 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0331953 |
| ZNF638 | zinc finger protein 638 | -0.0330249 |
| MEF2A | myocyte enhancer factor 2A | -0.0326726 |
| RPS20 | ribosomal protein S20 | -0.0323567 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0316253 |
| RPS19 | ribosomal protein S19 | -0.0312745 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0307402 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0305639 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0300342 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0298443 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0290371 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0287581 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0283919 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0283678 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0282876 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0281393 |
| PGK1 | phosphoglycerate kinase 1 | -0.0281345 |
| VEGFA | vascular endothelial growth factor A | -0.0280471 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0277063 |
| RPL12 | ribosomal protein L12 | -0.0277058 |
| FN1 | fibronectin 1 | -0.0276943 |
| PKM | pyruvate kinase, muscle | -0.0272471 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0271469 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0271079 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0268545 |
| RPS21 | ribosomal protein S21 | -0.0262025 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0259835 |
| RPL11 | ribosomal protein L11 | -0.0259204 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0258785 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0256929 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0256494 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0255231 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0251081 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0250292 |
| LOXL2 | lysyl oxidase-like 2 | -0.0249399 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0248329 |
| SLC43A3 | solute carrier family 43, member 3 | -0.0245599 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0243108 |
| RPL31 | ribosomal protein L31 | -0.0241665 |
| RPL28 | ribosomal protein L28 | -0.0241123 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0240797 |
| RPS25 | ribosomal protein S25 | -0.023856 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0238281 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0237925 |
| NABP1 | nucleic acid binding protein 1 | -0.0237161 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0234852 |
| HLA-B | major histocompatibility complex, class I, B | -0.0231564 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0224126 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0223093 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.022118 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0220273 |
| RPLP2 | ribosomal protein, large, P2 | -0.0219982 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.021942 |
| FBXO11 | F-box protein 11 | -0.0218007 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0217938 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0217311 |
| RPL34 | ribosomal protein L34 | -0.0216495 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0216377 |
| SEC61G | Sec61 gamma subunit | -0.0215514 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0215011 |
| RPL32 | ribosomal protein L32 | -0.0211032 |
| RASAL2 | RAS protein activator like 2 | -0.0210266 |
| TMEM165 | transmembrane protein 165 | -0.0207642 |
| RPL19 | ribosomal protein L19 | -0.0206965 |
| PCM1 | pericentriolar material 1 | -0.0204758 |
| ZNF395 | zinc finger protein 395 | -0.0204723 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0204191 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0203034 |
| PMP22 | peripheral myelin protein 22 | -0.0202653 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0202504 |
| PHF14 | PHD finger protein 14 | -0.0201957 |
| MTDH | metadherin | -0.020148 |
