| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Naproxen_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.18553 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.168355 |
| PTMA | prothymosin, alpha | 0.0946162 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0931617 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0916821 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0877788 |
| TPI1 | triosephosphate isomerase 1 | 0.0718255 |
| TPM3 | tropomyosin 3 | 0.0619738 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.056723 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0540915 |
| RPS2 | ribosomal protein S2 | 0.0538937 |
| RPL37A | ribosomal protein L37a | 0.053877 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0527847 |
| SET | SET nuclear proto-oncogene | 0.0517567 |
| MKI67 | marker of proliferation Ki-67 | 0.0512278 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0504136 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0496401 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0483352 |
| CTTN | cortactin | 0.0481632 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0477684 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0473108 |
| RPS12 | ribosomal protein S12 | 0.0472684 |
| RPL4 | ribosomal protein L4 | 0.0444256 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0436843 |
| PTK2 | protein tyrosine kinase 2 | 0.0433769 |
| CENPF | centromere protein F, 350/400kDa | 0.0425706 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0420219 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0419676 |
| PCBP2 | poly(rC) binding protein 2 | 0.0407193 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0406179 |
| TUBA1B | tubulin, alpha 1b | 0.0397897 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.039705 |
| RPS3 | ribosomal protein S3 | 0.0396873 |
| TUBA1C | tubulin, alpha 1c | 0.0389648 |
| WDR43 | WD repeat domain 43 | 0.0381062 |
| RPS27A | ribosomal protein S27a | 0.0381 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0375589 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0369159 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0368574 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0366672 |
| RAD51B | RAD51 paralog B | 0.0356073 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0353228 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0349519 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0348208 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0346357 |
| TLN1 | talin 1 | 0.033731 |
| PNN | pinin, desmosome associated protein | 0.0334443 |
| EXOC4 | exocyst complex component 4 | 0.0333682 |
| HDGF | hepatoma-derived growth factor | 0.0327795 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0321394 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.031938 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0319295 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0318088 |
| RBM39 | RNA binding motif protein 39 | 0.0317261 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0309666 |
| H1-4 | H1.4 linker histone, cluster member | 0.0306836 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0306206 |
| TLK1 | tousled-like kinase 1 | 0.0305853 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0305464 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0299924 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.029988 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0292913 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0292364 |
| H1-3 | H1.3 linker histone, cluster member | 0.0292299 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0289378 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0288248 |
| AHNAK | AHNAK nucleoprotein | 0.0283892 |
| PRELID2 | PRELI domain containing 2 | 0.028325 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0282548 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0280454 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0279751 |
| GOLGA4 | golgin A4 | 0.0279383 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0278376 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0277851 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0275874 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0274186 |
| FAM168A | family with sequence similarity 168, member A | 0.027292 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0270295 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.026901 |
| PAPOLA | poly(A) polymerase alpha | 0.0268507 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0268082 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0267287 |
| DST | dystonin | 0.0266902 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0266844 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0265814 |
| RASA2 | RAS p21 protein activator 2 | 0.0263781 |
| PUM2 | pumilio RNA-binding family member 2 | 0.026356 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0261824 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.0257209 |
| HMGB2 | high mobility group box 2 | 0.0255609 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0253239 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0251539 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0250888 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0249585 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0249289 |
| RPL14 | ribosomal protein L14 | 0.024449 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0242382 |
| ANO6 | anoctamin 6 | 0.0242012 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0241699 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0240479 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.185332 |
| TXNRD1 | thioredoxin reductase 1 | -0.119414 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0874141 |
| POTEF | POTE ankyrin domain family, member F | -0.0670181 |
| OSMR | oncostatin M receptor | -0.0578012 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0520886 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0463678 |
| NABP1 | nucleic acid binding protein 1 | -0.0459613 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0430787 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0428049 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.042499 |
| FTL | ferritin, light polypeptide | -0.0419444 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0418567 |
| RPLP0 | ribosomal protein, large, P0 | -0.040776 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0403827 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0400395 |
| COPA | coatomer protein complex, subunit alpha | -0.0398495 |
| KLF6 | Kruppel-like factor 6 | -0.0394574 |
| BSG | basigin (Ok blood group) | -0.039152 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.038163 |
| RPS4X | ribosomal protein S4, X-linked | -0.0378635 |
| EGR1 | early growth response 1 | -0.0375115 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0362862 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0360725 |
| MORF4L2 | mortality factor 4 like 2 | -0.0355513 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.035252 |
| TWF1 | twinfilin actin binding protein 1 | -0.0350268 |
| ZNF638 | zinc finger protein 638 | -0.0346177 |
| YAP1 | Yes-associated protein 1 | -0.0344006 |
| CCNL1 | cyclin L1 | -0.0343084 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0336895 |
| ARF4 | ADP-ribosylation factor 4 | -0.0325189 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0324852 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0320572 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.031717 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.031663 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0314043 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0312078 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0308684 |
| PFN1 | profilin 1 | -0.0295985 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.029433 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.029343 |
| RPLP1 | ribosomal protein, large, P1 | -0.0291381 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0283816 |
| PKM | pyruvate kinase, muscle | -0.0277308 |
| UBAP2L | ubiquitin associated protein 2-like | -0.0272994 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0271487 |
| SETX | senataxin | -0.0271392 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0269962 |
| HMGA1 | high mobility group AT-hook 1 | -0.0264109 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0263567 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0261798 |
| YBX3 | Y box binding protein 3 | -0.0259608 |
| IGF2 | insulin-like growth factor 2 | -0.0259288 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.025915 |
| MATR3 | matrin 3 | -0.0258138 |
| ADAR | adenosine deaminase, RNA-specific | -0.0255502 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0253068 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0252213 |
| VIM | vimentin | -0.0252183 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0248675 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0247753 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0245482 |
| RPL8 | ribosomal protein L8 | -0.0243534 |
| SETD5 | SET domain containing 5 | -0.0242084 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0241293 |
| PTEN | phosphatase and tensin homolog | -0.0238742 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0237998 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0237886 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.02367 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0236009 |
| COG5 | component of oligomeric golgi complex 5 | -0.0235145 |
| WDR45B | WD repeat domain 45B | -0.0233247 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0231563 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0231372 |
| POGZ | pogo transposable element with ZNF domain | -0.0230667 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0230516 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0228407 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0226925 |
| CCND1 | cyclin D1 | -0.0226468 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0226096 |
| PLSCR1 | phospholipid scramblase 1 | -0.0225529 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0223736 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0223442 |
| PDE10A | phosphodiesterase 10A | -0.0222125 |
| TMEM87A | transmembrane protein 87A | -0.0221638 |
| TMPO | thymopoietin | -0.0220262 |
| FLOT1 | flotillin 1 | -0.0219865 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0218751 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0218725 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0218542 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0218363 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0218134 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0217426 |
| ADIPOR2 | adiponectin receptor 2 | -0.0216779 |
| ATF6 | activating transcription factor 6 | -0.0214481 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0213805 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0213197 |
| HELZ | helicase with zinc finger | -0.0213095 |
| LIMA1 | LIM domain and actin binding 1 | -0.0211395 |
