| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.124474 |
| RPS27A | ribosomal protein S27a | 0.0972003 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0947872 |
| UBC | ubiquitin C | 0.0934823 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0912569 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0857483 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0788817 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0775342 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0768613 |
| TBXT | T-box transcription factor T | 0.0765396 |
| EFNA5 | ephrin-A5 | 0.0743797 |
| PTMA | prothymosin, alpha | 0.0645309 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0638265 |
| RPL4 | ribosomal protein L4 | 0.0620265 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.059546 |
| PCBP2 | poly(rC) binding protein 2 | 0.0563878 |
| GOLGA4 | golgin A4 | 0.054315 |
| RBM39 | RNA binding motif protein 39 | 0.0532369 |
| PRRC2C | proline-rich coiled-coil 2C | 0.052575 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0523091 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0520001 |
| WDR43 | WD repeat domain 43 | 0.0507194 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0497971 |
| SET | SET nuclear proto-oncogene | 0.0482738 |
| RPS12 | ribosomal protein S12 | 0.047879 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0468352 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0466973 |
| AHNAK | AHNAK nucleoprotein | 0.0466925 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0463239 |
| RPS2 | ribosomal protein S2 | 0.046242 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0460549 |
| TMSB10 | thymosin beta 10 | 0.0447783 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0440387 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0430373 |
| TPM3 | tropomyosin 3 | 0.0425529 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.042049 |
| ASPH | aspartate beta-hydroxylase | 0.0410738 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0392921 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.039232 |
| RPL37A | ribosomal protein L37a | 0.0385931 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0385335 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0383302 |
| NGLY1 | N-glycanase 1 | 0.0371859 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0367424 |
| PNN | pinin, desmosome associated protein | 0.0366228 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0365436 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0362053 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0352503 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0352127 |
| RTN4 | reticulon 4 | 0.0344956 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0344733 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0343873 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0343681 |
| NOP58 | NOP58 ribonucleoprotein | 0.0339075 |
| FLNA | filamin A, alpha | 0.0338488 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0330562 |
| RACK1 | receptor for activated C kinase 1 | 0.0325594 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0325267 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0318896 |
| CALR | calreticulin | 0.0318616 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0315195 |
| FAM13A | family with sequence similarity 13, member A | 0.031244 |
| RNF145 | ring finger protein 145 | 0.0309503 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0291066 |
| CANX | calnexin | 0.0285399 |
| RPS17 | ribosomal protein S17 | 0.0280783 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0274862 |
| RPL5 | ribosomal protein L5 | 0.0272688 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0271335 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0270519 |
| ANXA1 | annexin A1 | 0.0270267 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0267479 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.026687 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.026682 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0264116 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0258286 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0257895 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0257878 |
| ATP13A3 | ATPase type 13A3 | 0.0254291 |
| ANO6 | anoctamin 6 | 0.0253867 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0253533 |
| PLCB4 | phospholipase C, beta 4 | 0.0253399 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0251224 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0250827 |
| NCKAP1 | NCK-associated protein 1 | 0.0250476 |
| HDGF | hepatoma-derived growth factor | 0.0249885 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0248765 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0248195 |
| PAPOLA | poly(A) polymerase alpha | 0.0247771 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0247717 |
| STC1 | stanniocalcin 1 | 0.0246601 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0244768 |
| SPAG9 | sperm associated antigen 9 | 0.0244527 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.024115 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0240506 |
| H1-4 | H1.4 linker histone, cluster member | 0.0240476 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0239989 |
| FLNB | filamin B, beta | 0.0236682 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0234469 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0233058 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.222821 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.139592 |
| PM20D1 | peptidase M20 domain containing 1 | -0.114419 |
| RPLP1 | ribosomal protein, large, P1 | -0.113207 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.111391 |
| GDA | guanine deaminase | -0.0992819 |
| MT2A | metallothionein 2A | -0.0987746 |
| RPL35A | ribosomal protein L35a | -0.0952667 |
| FTL | ferritin, light polypeptide | -0.0943779 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0819227 |
| COL5A2 | collagen, type V, alpha 2 | -0.0723392 |
| FN1 | fibronectin 1 | -0.0691822 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0607793 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0582956 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0565047 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0553938 |
| VCL | vinculin | -0.0522386 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0504196 |
| RPLP0 | ribosomal protein, large, P0 | -0.0499319 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0488751 |
| RPS4X | ribosomal protein S4, X-linked | -0.0487637 |
| RPS24 | ribosomal protein S24 | -0.0471554 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0454089 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0453571 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0437832 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0430756 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0409368 |
| LDHA | lactate dehydrogenase A | -0.0362393 |
| MT1X | metallothionein 1X | -0.0355167 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0350258 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0341766 |
| MAP7 | microtubule-associated protein 7 | -0.0338869 |
| MYOF | myoferlin | -0.0336196 |
| CD109 | CD109 molecule | -0.0324361 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0322396 |
| RPS19 | ribosomal protein S19 | -0.0305341 |
| PDE10A | phosphodiesterase 10A | -0.0303374 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0297778 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0292751 |
| RPS28 | ribosomal protein S28 | -0.0290815 |
| NTN4 | netrin 4 | -0.0289735 |
| INTS6 | integrator complex subunit 6 | -0.028901 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0287455 |
| POTEF | POTE ankyrin domain family, member F | -0.0286797 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0286414 |
| RPS23 | ribosomal protein S23 | -0.0284985 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0276387 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0274887 |
| SMAD2 | SMAD family member 2 | -0.0274645 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0273132 |
| RPS20 | ribosomal protein S20 | -0.0272697 |
| RPL31 | ribosomal protein L31 | -0.0270875 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0264201 |
| BSG | basigin (Ok blood group) | -0.0263952 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0262266 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0258471 |
| ACTG1 | actin gamma 1 | -0.0256017 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.025408 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0253946 |
| PKM | pyruvate kinase, muscle | -0.0253894 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | -0.0250787 |
| RPL12 | ribosomal protein L12 | -0.0247548 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0240887 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0240713 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0240491 |
| RPL38 | ribosomal protein L38 | -0.0237958 |
| RAB31 | RAB31, member RAS oncogene family | -0.0234445 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0232414 |
| RPS14 | ribosomal protein S14 | -0.0229983 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0226374 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0224763 |
| KYNU | kynureninase | -0.0224479 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0219168 |
| TMEM144 | transmembrane protein 144 | -0.021887 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0217144 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0215724 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0214823 |
| KRT19 | keratin 19, type I | -0.0213244 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0209918 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0208865 |
| FOXK1 | forkhead box K1 | -0.0208119 |
| EGR1 | early growth response 1 | -0.0201969 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0198081 |
| NABP1 | nucleic acid binding protein 1 | -0.0197733 |
| TPM4 | tropomyosin 4 | -0.0196122 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.018986 |
| TNPO1 | transportin 1 | -0.0185752 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0185531 |
| NRG1 | neuregulin 1 | -0.018492 |
| MALT1 | MALT1 paracaspase | -0.0184529 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0182027 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.01796 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0179086 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0177559 |
| CST3 | cystatin C | -0.0175736 |
| RAD51B | RAD51 paralog B | -0.0169854 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0168745 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0168249 |
| PYGL | phosphorylase, glycogen, liver | -0.016547 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0164512 |
